Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     509
XP_006718908                                                           20     509
XP_005271621                                                           20     509
XP_006718907                                                           20     509
XP_006718906                                                           20     509
XP_005271619                                                           20     509
XP_005271618                                                           20     509
NP_001070650                                                           17    2528
NP_036550                                                              17    2528
NP_443132                                                              17    2528
NP_937757                                                              17    2528
NP_937756                                                              17    2528
XP_005257253                                                           17    2528
XP_005257252                                                           17    2528
NP_000383                                                              17    4312
NP_060542                                                              17    4312
NP_003777                                                              17    4312
NP_001243089                                                           17    4312
NP_079273                                                              17    4312
XP_005257820                                                           17    4312
XP_006721016                                                           17    4312
XP_006717694                                                           17    4312
XP_006717693                                                           17    4312
NP_004987                                                              16    5631
NP_055501                                                              16    5631
XP_005259501                                                           16    5631
XP_006720948                                                           16    5631
XP_006720947                                                           16    5631
XP_005255386                                                           16    5631
XP_005255385                                                           16    5631
XP_005255384                                                           16    5631
NP_116196                                                              16    7355
NP_835363                                                              16    7355
NP_001245381                                                           16    7355
NP_001245382                                                           16    7355
NP_001138766                                                           16    7355
NP_001138767                                                           16    7355
NP_060767                                                              16    7355
NP_001138765                                                           16    7355
NP_001159506                                                           16    7355
NP_940940                                                              16    7355
NP_009129                                                              16    7355
NP_001177396                                                           16    7355
XP_006717580                                                           16    7355
XP_006717579                                                           16    7355
XP_005265374                                                           16    7355
XP_005265373                                                           16    7355
NP_054876                                                              16    7355
NP_003822                                                              16    7355
NP_001274103                                                           15    9605
NP_000343                                                              15    9605
NP_005682                                                              15    9605
NP_064693                                                              15    9605
NP_001278340                                                           15    9605
NP_620305                                                              15    9605
NP_115571                                                              15    9605
NP_114141                                                              15    9605
NP_001681                                                              15    9605
XP_006724107                                                           15    9605
XP_006724106                                                           15    9605
XP_005268766                                                           15    9605
XP_005253348                                                           15    9605
XP_005253347                                                           15    9605
XP_006719088                                                           15    9605
XP_005253346                                                           15    9605
XP_005253344                                                           15    9605
XP_005253345                                                           15    9605
XP_005253343                                                           15    9605
XP_005253341                                                           15    9605
XP_006718349                                                           15    9605
NP_001408                                                              15    9605
>NP_000042
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KGINISADQ 9
            KGINI ADQ
Sbjct: 2643 KGINIPADQ 2651
>XP_006718908
          Length = 1708

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KGINISADQ 9
            KGINI ADQ
Sbjct: 1295 KGINIPADQ 1303
>XP_005271621
          Length = 2708

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KGINISADQ 9
            KGINI ADQ
Sbjct: 2295 KGINIPADQ 2303
>XP_006718907
          Length = 3050

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KGINISADQ 9
            KGINI ADQ
Sbjct: 2637 KGINIPADQ 2645
>XP_006718906
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KGINISADQ 9
            KGINI ADQ
Sbjct: 2643 KGINIPADQ 2651
>XP_005271619
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KGINISADQ 9
            KGINI ADQ
Sbjct: 2643 KGINIPADQ 2651
>XP_005271618
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KGINISADQ 9
            KGINI ADQ
Sbjct: 2643 KGINIPADQ 2651
>NP_001070650
          Length = 516

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KGINISADQ 9
           +G+N+SA+Q
Sbjct: 275 QGVNVSANQ 283
>NP_036550
          Length = 492

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KGINISADQ 9
           +G+N+SA+Q
Sbjct: 275 QGVNVSANQ 283
>NP_443132
          Length = 3538

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    KGINISA 7
            KGINISA
Sbjct: 1173 KGINISA 1179
>NP_937757
          Length = 3667

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    KGINISA 7
            KGINISA
Sbjct: 1237 KGINISA 1243
>NP_937756
          Length = 3707

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    KGINISA 7
            KGINISA
Sbjct: 1277 KGINISA 1283
>XP_005257253
          Length = 492

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KGINISADQ 9
           +G+N+SA+Q
Sbjct: 275 QGVNVSANQ 283
>XP_005257252
          Length = 516

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KGINISADQ 9
           +G+N+SA+Q
Sbjct: 275 QGVNVSANQ 283
>NP_000383
          Length = 1545

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           KGIN+S  Q
Sbjct: 757 KGINLSGGQ 765
>NP_060542
          Length = 2144

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KGINISADQ 9
            KGI+++A+Q
Sbjct: 1152 KGISVNAEQ 1160
>NP_003777
          Length = 1527

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           KGIN+S  Q
Sbjct: 747 KGINLSGGQ 755
>NP_001243089
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KGINISADQ 9
           K IN+S+DQ
Sbjct: 436 KKINLSSDQ 444
>NP_079273
          Length = 682

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KGINISADQ 9
           K IN+S+DQ
Sbjct: 436 KKINLSSDQ 444
>XP_005257820
          Length = 1463

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           KGIN+S  Q
Sbjct: 683 KGINLSGGQ 691
>XP_006721016
          Length = 682

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KGINISADQ 9
           K IN+S+DQ
Sbjct: 436 KKINLSSDQ 444
>XP_006717694
          Length = 895

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           KGIN+S  Q
Sbjct: 757 KGINLSGGQ 765
>XP_006717693
          Length = 1313

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           KGIN+S  Q
Sbjct: 525 KGINLSGGQ 533
>NP_004987
          Length = 1531

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           KG+N+S  Q
Sbjct: 764 KGVNLSGGQ 772
>NP_055501
          Length = 1070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           KG+N+  DQ
Sbjct: 636 KGMNLPTDQ 644
>XP_005259501
          Length = 1070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           KG+N+  DQ
Sbjct: 636 KGMNLPTDQ 644
>XP_006720948
          Length = 1401

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           KG+N+S  Q
Sbjct: 634 KGVNLSGGQ 642
>XP_006720947
          Length = 1466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           KG+N+S  Q
Sbjct: 764 KGVNLSGGQ 772
>XP_005255386
          Length = 1472

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           KG+N+S  Q
Sbjct: 705 KGVNLSGGQ 713
>XP_005255385
          Length = 1485

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           KG+N+S  Q
Sbjct: 718 KGVNLSGGQ 726
>XP_005255384
          Length = 1489

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           KG+N+S  Q
Sbjct: 722 KGVNLSGGQ 730
>NP_116196
          Length = 1094

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KGINIS 6
           KGINIS
Sbjct: 448 KGINIS 453
>NP_835363
          Length = 1043

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KGINIS 6
           KGINIS
Sbjct: 397 KGINIS 402
>NP_001245381
          Length = 986

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KGINIS 6
           KGINIS
Sbjct: 323 KGINIS 328
>NP_001245382
          Length = 969

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KGINIS 6
           KGINIS
Sbjct: 323 KGINIS 328
>NP_001138766
          Length = 612

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KGINIS 6
           KGINIS
Sbjct: 177 KGINIS 182
>NP_001138767
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KGINIS 6
           KGINIS
Sbjct: 219 KGINIS 224
>NP_060767
          Length = 654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KGINIS 6
           KGINIS
Sbjct: 219 KGINIS 224
>NP_001138765
          Length = 636

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KGINIS 6
           KGINIS
Sbjct: 219 KGINIS 224
>NP_001159506
          Length = 590

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGINISADQ 9
           +G+N +ADQ
Sbjct: 496 QGVNHAADQ 504
>NP_940940
          Length = 247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGINISADQ 9
           +G+N +ADQ
Sbjct: 153 QGVNHAADQ 161
>NP_009129
          Length = 275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           K +NI ADQ
Sbjct: 210 KKLNIPADQ 218
>NP_001177396
          Length = 1346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGINISADQ 9
           KG+ ISA++
Sbjct: 132 KGLRISAEE 140
>XP_006717580
          Length = 1043

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KGINIS 6
           KGINIS
Sbjct: 397 KGINIS 402
>XP_006717579
          Length = 1180

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KGINIS 6
           KGINIS
Sbjct: 534 KGINIS 539
>XP_005265374
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KGINIS 6
           KGINIS
Sbjct: 219 KGINIS 224
>XP_005265373
          Length = 599

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KGINIS 6
           KGINIS
Sbjct: 219 KGINIS 224
>NP_054876
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  KGINISADQ 9
          +G+ ++ADQ
Sbjct: 91 RGVGLTADQ 99
>NP_003822
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GINISAD 8
           G+NI+AD
Sbjct: 470 GLNITAD 476
>NP_001274103
          Length = 1582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           +GIN+S  Q
Sbjct: 826 RGINLSGGQ 834
>NP_000343
          Length = 1581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           +GIN+S  Q
Sbjct: 825 RGINLSGGQ 833
>NP_005682
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           +GIN+S  Q
Sbjct: 808 RGINLSGGQ 816
>NP_064693
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           +GIN+S  Q
Sbjct: 808 RGINLSGGQ 816
>NP_001278340
          Length = 2108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KGINISA 7
            KGIN+S+
Sbjct: 1485 KGINLSS 1491
>NP_620305
          Length = 2426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KGINISA 7
            KGIN+S+
Sbjct: 1485 KGINLSS 1491
>NP_115571
          Length = 2303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KGINISA 7
            KGIN+S+
Sbjct: 1485 KGINLSS 1491
>NP_114141
          Length = 5635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    KGINISAD 8
            KG+ I+AD
Sbjct: 5134 KGLTIAAD 5141
>NP_001681
          Length = 617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   KGINISA 7
           +G+N+SA
Sbjct: 120 RGVNVSA 126
>XP_006724107
          Length = 2298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KGINISA 7
            KGIN+S+
Sbjct: 1485 KGINLSS 1491
>XP_006724106
          Length = 2459

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KGINISA 7
            KGIN+S+
Sbjct: 1485 KGINLSS 1491
>XP_005268766
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KGINISA 7
           +G+NISA
Sbjct: 117 RGLNISA 123
>XP_005253348
          Length = 1229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           +GIN+S  Q
Sbjct: 808 RGINLSGGQ 816
>XP_005253347
          Length = 1502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           +GIN+S  Q
Sbjct: 761 RGINLSGGQ 769
>XP_006719088
          Length = 1536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           +GIN+S  Q
Sbjct: 795 RGINLSGGQ 803
>XP_005253346
          Length = 1536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           +GIN+S  Q
Sbjct: 795 RGINLSGGQ 803
>XP_005253344
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           +GIN+S  Q
Sbjct: 808 RGINLSGGQ 816
>XP_005253345
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           +GIN+S  Q
Sbjct: 808 RGINLSGGQ 816
>XP_005253343
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           +GIN+S  Q
Sbjct: 808 RGINLSGGQ 816
>XP_005253341
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           +GIN+S  Q
Sbjct: 808 RGINLSGGQ 816
>XP_006718349
          Length = 1646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGINISADQ 9
           +GIN+S  Q
Sbjct: 825 RGINLSGGQ 833
>NP_001408
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KGINISA 7
           +G+NISA
Sbjct: 117 RGLNISA 123
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.127    0.325 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 366,119
Number of extensions: 527
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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