Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              21     229
NP_001120972                                                           21     229
XP_006716054                                                           21     229
XP_006716053                                                           21     229
XP_006716052                                                           21     229
XP_006716051                                                           21     229
NP_001276968                                                           18    1482
NP_001276969                                                           18    1482
NP_001122401                                                           18    1482
NP_002933                                                              18    1482
XP_006713342                                                           18    1482
NP_001139317                                                           18    1935
NP_598334                                                              18    1935
NP_002932                                                              18    1935
NP_612429                                                              18    1935
XP_005267356                                                           18    1935
XP_006713341                                                           18    1935
XP_006713340                                                           18    1935
XP_006713339                                                           18    1935
NP_001240317                                                           17    3301
NP_001240316                                                           17    3301
NP_006605                                                              17    3301
XP_006713004                                                           17    3301
XP_006713003                                                           17    3301
XP_006713002                                                           17    3301
XP_006713001                                                           17    3301
NP_056384                                                              17    4312
NP_001129599                                                           17    4312
NP_001265181                                                           17    4312
NP_995322                                                              17    4312
NP_640338                                                              17    4312
XP_005254365                                                           17    4312
XP_006711331                                                           17    4312
XP_005245141                                                           17    4312
XP_005245139                                                           17    4312
XP_005245138                                                           17    4312
XP_005245137                                                           17    4312
XP_005245136                                                           17    4312
NP_008846                                                              16    5631
NP_004237                                                              16    5631
XP_005256918                                                           16    5631
NP_443190                                                              16    7355
NP_001182568                                                           16    7355
NP_078928                                                              16    7355
XP_006717999                                                           16    7355
XP_005251206                                                           16    7355
NP_068598                                                              16    7355
NP_001166935                                                           15    9605
NP_060111                                                              15    9605
NP_001166934                                                           15    9605
NP_001166936                                                           15    9605
NP_653234                                                              15    9605
XP_006719559                                                           15    9605
XP_006719558                                                           15    9605
XP_005269072                                                           15    9605
XP_005269071                                                           15    9605
XP_005269070                                                           15    9605
XP_006719557                                                           15    9605
XP_005269069                                                           15    9605
XP_006719556                                                           15    9605
XP_005269068                                                           15    9605
XP_005269067                                                           15    9605
XP_005269066                                                           15    9605
XP_005269065                                                           15    9605
XP_005269064                                                           15    9605
XP_006713027                                                           15    9605
XP_006713026                                                           15    9605
XP_006713025                                                           15    9605
XP_006713024                                                           15    9605
NP_001139669                                                           15    9605
>NP_000236
          Length = 1390

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KGDLTIANI 9
           KGDLTIAN+
Sbjct: 447 KGDLTIANL 455
>NP_001120972
          Length = 1408

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KGDLTIANI 9
           KGDLTIAN+
Sbjct: 447 KGDLTIANL 455
>XP_006716054
          Length = 960

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  KGDLTIANI 9
          KGDLTIAN+
Sbjct: 17 KGDLTIANL 25
>XP_006716053
          Length = 960

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  KGDLTIANI 9
          KGDLTIAN+
Sbjct: 17 KGDLTIANL 25
>XP_006716052
          Length = 1409

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KGDLTIANI 9
           KGDLTIAN+
Sbjct: 466 KGDLTIANL 474
>XP_006716051
          Length = 1427

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KGDLTIANI 9
           KGDLTIAN+
Sbjct: 466 KGDLTIANL 474
>NP_001276968
          Length = 1382

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   GDLTIANI 9
           GDLTI NI
Sbjct: 378 GDLTITNI 385
>NP_001276969
          Length = 1443

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   GDLTIANI 9
           GDLTI NI
Sbjct: 378 GDLTITNI 385
>NP_001122401
          Length = 1394

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   GDLTIANI 9
           GDLTI NI
Sbjct: 390 GDLTITNI 397
>NP_002933
          Length = 1378

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   GDLTIANI 9
           GDLTI NI
Sbjct: 374 GDLTITNI 381
>XP_006713342
          Length = 1205

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   GDLTIANI 9
           GDLTI NI
Sbjct: 394 GDLTITNI 401
>NP_001139317
          Length = 1551

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GDLTIANI 9
           GDLTI N+
Sbjct: 375 GDLTITNV 382
>NP_598334
          Length = 1606

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GDLTIANI 9
           GDLTI N+
Sbjct: 375 GDLTITNV 382
>NP_002932
          Length = 1651

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GDLTIANI 9
           GDLTI N+
Sbjct: 411 GDLTITNV 418
>NP_612429
          Length = 5795

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KGDLTIAN 8
            +GDLT+AN
Sbjct: 2136 QGDLTLAN 2143
>XP_005267356
          Length = 5695

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KGDLTIAN 8
            +GDLT+AN
Sbjct: 2036 QGDLTLAN 2043
>XP_006713341
          Length = 1600

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GDLTIANI 9
           GDLTI N+
Sbjct: 360 GDLTITNV 367
>XP_006713340
          Length = 1615

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GDLTIANI 9
           GDLTI N+
Sbjct: 375 GDLTITNV 382
>XP_006713339
          Length = 1616

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GDLTIANI 9
           GDLTI N+
Sbjct: 376 GDLTITNV 383
>NP_001240317
          Length = 1171

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           KGDL  AN+
Sbjct: 185 KGDLYFANV 193
>NP_001240316
          Length = 1208

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           KGDL  AN+
Sbjct: 185 KGDLYFANV 193
>NP_006605
          Length = 1224

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           KGDL  AN+
Sbjct: 185 KGDLYFANV 193
>XP_006713004
          Length = 1171

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           KGDL  AN+
Sbjct: 185 KGDLYFANV 193
>XP_006713003
          Length = 1224

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           KGDL  AN+
Sbjct: 185 KGDLYFANV 193
>XP_006713002
          Length = 1224

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           KGDL  AN+
Sbjct: 185 KGDLYFANV 193
>XP_006713001
          Length = 1224

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           KGDL  AN+
Sbjct: 185 KGDLYFANV 193
>NP_056384
          Length = 863

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KGDLTIANI 9
           KG LTI+NI
Sbjct: 519 KGWLTISNI 527
>NP_001129599
          Length = 859

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KGDLTIANI 9
           KG LTI+NI
Sbjct: 519 KGWLTISNI 527
>NP_001265181
          Length = 555

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KGDLTIANI 9
           KG LTI+NI
Sbjct: 519 KGWLTISNI 527
>NP_995322
          Length = 500

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGDLTIANI 9
           KGD+ ++NI
Sbjct: 395 KGDMAMSNI 403
>NP_640338
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DLTIANI 9
           DLT+AN+
Sbjct: 204 DLTVANV 210
>XP_005254365
          Length = 500

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KGDLTIANI 9
           KGD+ ++NI
Sbjct: 395 KGDMAMSNI 403
>XP_006711331
          Length = 565

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KGDLTIANI 9
           KG LTI+NI
Sbjct: 529 KGWLTISNI 537
>XP_005245141
          Length = 608

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KGDLTIANI 9
           KG LTI+NI
Sbjct: 529 KGWLTISNI 537
>XP_005245139
          Length = 763

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KGDLTIANI 9
           KG LTI+NI
Sbjct: 419 KGWLTISNI 427
>XP_005245138
          Length = 862

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KGDLTIANI 9
           KG LTI+NI
Sbjct: 529 KGWLTISNI 537
>XP_005245137
          Length = 869

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KGDLTIANI 9
           KG LTI+NI
Sbjct: 529 KGWLTISNI 537
>XP_005245136
          Length = 873

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KGDLTIANI 9
           KG LTI+NI
Sbjct: 529 KGWLTISNI 537
>NP_008846
          Length = 350

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GDLTIAN 8
           GD TIAN
Sbjct: 243 GDYTIAN 249
>NP_004237
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KGDLTIAN 8
           +GD+T+AN
Sbjct: 535 EGDVTMAN 542
>XP_005256918
          Length = 400

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KGDLTIAN 8
           +GD+T+AN
Sbjct: 382 EGDVTMAN 389
>NP_443190
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           K DL ++NI
Sbjct: 185 KSDLAVSNI 193
>NP_001182568
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           K DL ++NI
Sbjct: 185 KSDLAVSNI 193
>NP_078928
          Length = 2015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DLTIANI 9
           DLTI+N+
Sbjct: 604 DLTISNV 610
>XP_006717999
          Length = 1207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  KGDLTI 6
          KGDLT+
Sbjct: 34 KGDLTV 39
>XP_005251206
          Length = 317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           K DL ++NI
Sbjct: 185 KSDLAVSNI 193
>NP_068598
          Length = 764

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   GDLTIANI 9
           GDL  ANI
Sbjct: 341 GDLACANI 348
>NP_001166935
          Length = 1674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 977 EGDKNVANI 985
>NP_060111
          Length = 1661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 964 EGDKNVANI 972
>NP_001166934
          Length = 1637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 964 EGDKNVANI 972
>NP_001166936
          Length = 1621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 941 EGDKNVANI 949
>NP_653234
          Length = 1107

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           KGDL  AN+
Sbjct: 610 KGDLIGANL 618
>XP_006719559
          Length = 1650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 964 EGDKNVANI 972
>XP_006719558
          Length = 1644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 964 EGDKNVANI 972
>XP_005269072
          Length = 1607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 977 EGDKNVANI 985
>XP_005269071
          Length = 1614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 977 EGDKNVANI 985
>XP_005269070
          Length = 1627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 977 EGDKNVANI 985
>XP_006719557
          Length = 1631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 977 EGDKNVANI 985
>XP_005269069
          Length = 1632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 977 EGDKNVANI 985
>XP_006719556
          Length = 1655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 964 EGDKNVANI 972
>XP_005269068
          Length = 1657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 977 EGDKNVANI 985
>XP_005269067
          Length = 1662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 964 EGDKNVANI 972
>XP_005269066
          Length = 1668

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 977 EGDKNVANI 985
>XP_005269065
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 977 EGDKNVANI 985
>XP_005269064
          Length = 1675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           +GD  +ANI
Sbjct: 977 EGDKNVANI 985
>XP_006713027
          Length = 930

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           KGDL  AN+
Sbjct: 432 KGDLIGANL 440
>XP_006713026
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           KGDL  AN+
Sbjct: 488 KGDLIGANL 496
>XP_006713025
          Length = 1089

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           KGDL  AN+
Sbjct: 591 KGDLIGANL 599
>XP_006713024
          Length = 1108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KGDLTIANI 9
           KGDL  AN+
Sbjct: 610 KGDLIGANL 618
>NP_001139669
          Length = 7081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    KGDLTI 6
            KGD+TI
Sbjct: 4138 KGDITI 4143
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.140    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 452,603
Number of extensions: 582
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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