Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           20     390
NP_000242                                                              20     390
XP_005264389                                                           20     390
NP_002068                                                              17    3301
XP_006717126                                                           17    3301
XP_005251986                                                           17    3301
XP_006717125                                                           17    3301
NP_056076                                                              16    5631
NP_061883                                                              16    7355
NP_001188254                                                           16    7355
NP_002605                                                              16    7355
XP_005277849                                                           16    7355
XP_005257521                                                           16    7355
XP_005273027                                                           16    7355
XP_005273026                                                           16    7355
XP_005273025                                                           16    7355
NP_001009899                                                           15    9605
NP_001136357                                                           15    9605
XP_005247266                                                           15    9605
XP_005247265                                                           15    9605
NP_055363                                                              15    9605
>NP_001245210
          Length = 868

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KFQRQTANL 9
           KFQRQ ANL
Sbjct: 327 KFQRQAANL 335
>NP_000242
          Length = 934

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KFQRQTANL 9
           KFQRQ ANL
Sbjct: 393 KFQRQAANL 401
>XP_005264389
          Length = 921

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KFQRQTANL 9
           KFQRQ ANL
Sbjct: 393 KFQRQAANL 401
>NP_002068
          Length = 767

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KFQRQTANL 9
           +FQ+Q ANL
Sbjct: 495 EFQQQAANL 503
>XP_006717126
          Length = 767

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KFQRQTANL 9
           +FQ+Q ANL
Sbjct: 495 EFQQQAANL 503
>XP_005251986
          Length = 767

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KFQRQTANL 9
           +FQ+Q ANL
Sbjct: 495 EFQQQAANL 503
>XP_006717125
          Length = 767

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KFQRQTANL 9
           +FQ+Q ANL
Sbjct: 495 EFQQQAANL 503
>NP_056076
          Length = 1498

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   FQRQTAN 8
           +QRQT+N
Sbjct: 512 YQRQTSN 518
>NP_061883
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KFQRQTANL 9
           +F+RQTA L
Sbjct: 260 QFERQTAVL 268
>NP_001188254
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KFQRQTANL 9
           +F+R+TA+L
Sbjct: 226 QFKRETASL 234
>NP_002605
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KFQRQTANL 9
           +F+R+TA+L
Sbjct: 226 QFKRETASL 234
>XP_005277849
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KFQRQTANL 9
           +F+RQTA L
Sbjct: 260 QFERQTAVL 268
>XP_005257521
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KFQRQTANL 9
           +F+RQTA L
Sbjct: 260 QFERQTAVL 268
>XP_005273027
          Length = 394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KFQRQTANL 9
           +F+R+TA+L
Sbjct: 226 QFKRETASL 234
>XP_005273026
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KFQRQTANL 9
           +F+R+TA+L
Sbjct: 226 QFKRETASL 234
>XP_005273025
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   KFQRQTANL 9
           +F+R+TA+L
Sbjct: 226 QFKRETASL 234
>NP_001009899
          Length = 2245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QRQTANL 9
           Q+QTAN+
Sbjct: 177 QKQTANV 183
>NP_001136357
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KFQRQTAN 8
           KF  +TAN
Sbjct: 148 KFDEETAN 155
>XP_005247266
          Length = 2189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QRQTANL 9
           Q+QTAN+
Sbjct: 121 QKQTANV 127
>XP_005247265
          Length = 2211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QRQTANL 9
           Q+QTAN+
Sbjct: 143 QKQTANV 149
>NP_055363
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KFQRQTAN 8
           KF  +TAN
Sbjct: 148 KFDEETAN 155
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.126    0.332 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 377,215
Number of extensions: 345
Number of successful extensions: 21
Number of sequences better than 10000.0: 21
Number of HSP's gapped: 21
Number of HSP's successfully gapped: 21
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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