Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000312                                                              21     229
NP_001139669                                                           17    3301
NP_775858                                                              17    4312
NP_001165419                                                           17    4312
NP_076974                                                              17    4312
NP_001165420                                                           17    4312
XP_005260130                                                           17    4312
XP_006722946                                                           17    4312
XP_005273989                                                           17    4312
NP_006784                                                              16    5631
NP_054817                                                              16    5631
NP_001268421                                                           16    7355
NP_000170                                                              16    7355
NP_878918                                                              16    7355
NP_055995                                                              16    7355
NP_001268422                                                           16    7355
NP_001268423                                                           16    7355
NP_114477                                                              16    7355
NP_054723                                                              16    7355
XP_006720147                                                           16    7355
XP_005267517                                                           16    7355
XP_005267516                                                           16    7355
XP_005267515                                                           16    7355
XP_005267514                                                           16    7355
XP_005267513                                                           16    7355
XP_005267512                                                           16    7355
XP_005267511                                                           16    7355
XP_006714485                                                           16    7355
XP_005263418                                                           16    7355
XP_005263417                                                           16    7355
XP_006714484                                                           16    7355
XP_005263416                                                           16    7355
XP_006714483                                                           16    7355
XP_005263415                                                           16    7355
XP_005264070                                                           16    7355
XP_005264328                                                           16    7355
NP_789795                                                              16    7355
NP_001047                                                              16    7355
NP_742068                                                              15    9605
NP_001271230                                                           15    9605
NP_005899                                                              15    9605
NP_001271231                                                           15    9605
NP_940966                                                              15    9605
NP_061155                                                              15    9605
NP_057097                                                              15    9605
NP_848599                                                              15    9605
NP_937870                                                              15    9605
NP_937872                                                              15    9605
XP_006720621                                                           15    9605
XP_006720620                                                           15    9605
XP_006720619                                                           15    9605
XP_006720618                                                           15    9605
XP_006715810                                                           15    9605
XP_006715809                                                           15    9605
XP_006713970                                                           15    9605
XP_006713968                                                           15    9605
XP_006713081                                                           15    9605
XP_006711246                                                           15    9605
XP_005244978                                                           15    9605
XP_005244977                                                           15    9605
XP_005244976                                                           15    9605
XP_005244975                                                           15    9605
NP_002917                                                              15    9605
>NP_000312
          Length = 928

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KFQKINQML 9
           KFQKINQM+
Sbjct: 844 KFQKINQMV 852
>NP_001139669
          Length = 7081

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    KFQKINQ 7
            KF+KINQ
Sbjct: 1396 KFKKINQ 1402
>NP_775858
          Length = 523

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQKINQML 9
           FQ+I QML
Sbjct: 154 FQRIQQML 161
>NP_001165419
          Length = 176

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KFQKINQML 9
          +F+K N+ML
Sbjct: 37 RFEKTNEML 45
>NP_076974
          Length = 176

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KFQKINQML 9
          +F+K N+ML
Sbjct: 37 RFEKTNEML 45
>NP_001165420
          Length = 176

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KFQKINQML 9
          +F+K N+ML
Sbjct: 37 RFEKTNEML 45
>XP_005260130
          Length = 104

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KFQKINQML 9
          +F+K N+ML
Sbjct: 37 RFEKTNEML 45
>XP_006722946
          Length = 176

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  KFQKINQML 9
          +F+K N+ML
Sbjct: 37 RFEKTNEML 45
>XP_005273989
          Length = 477

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FQKINQML 9
           FQ+I QML
Sbjct: 154 FQRIQQML 161
>NP_006784
          Length = 256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FQKINQ 7
           FQK+NQ
Sbjct: 251 FQKVNQ 256
>NP_054817
          Length = 238

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FQKINQ 7
           FQK+NQ
Sbjct: 233 FQKVNQ 238
>NP_001268421
          Length = 1230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KFQKINQML 9
            +F+K+NQ L
Sbjct: 1192 EFEKMNQSL 1200
>NP_000170
          Length = 1360

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KFQKINQML 9
            +F+K+NQ L
Sbjct: 1322 EFEKMNQSL 1330
>NP_878918
          Length = 6907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FQKINQML 9
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>NP_055995
          Length = 6885

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FQKINQML 9
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>NP_001268422
          Length = 1058

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KFQKINQML 9
            +F+K+NQ L
Sbjct: 1020 EFEKMNQSL 1028
>NP_001268423
          Length = 1058

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KFQKINQML 9
            +F+K+NQ L
Sbjct: 1020 EFEKMNQSL 1028
>NP_114477
          Length = 932

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KFQKINQ 7
           KF+KIN+
Sbjct: 280 KFRKINE 286
>NP_054723
          Length = 820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KFQKINQ 7
           KF+KIN+
Sbjct: 280 KFRKINE 286
>XP_006720147
          Length = 4788

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FQKINQML 9
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267517
          Length = 6883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FQKINQML 9
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267516
          Length = 6884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FQKINQML 9
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267515
          Length = 6899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FQKINQML 9
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267514
          Length = 6908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FQKINQML 9
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267513
          Length = 6921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FQKINQML 9
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267512
          Length = 6922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FQKINQML 9
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267511
          Length = 6922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    FQKINQML 9
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_006714485
          Length = 1585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  KFQKINQ 7
          +F+KINQ
Sbjct: 26 RFRKINQ 32
>XP_005263418
          Length = 1654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KFQKINQ 7
           +F+KINQ
Sbjct: 142 RFRKINQ 148
>XP_005263417
          Length = 1660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KFQKINQ 7
           +F+KINQ
Sbjct: 142 RFRKINQ 148
>XP_006714484
          Length = 1685

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KFQKINQ 7
           +F+KINQ
Sbjct: 142 RFRKINQ 148
>XP_005263416
          Length = 1693

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KFQKINQ 7
           +F+KINQ
Sbjct: 142 RFRKINQ 148
>XP_006714483
          Length = 1695

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KFQKINQ 7
           +F+KINQ
Sbjct: 142 RFRKINQ 148
>XP_005263415
          Length = 1701

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KFQKINQ 7
           +F+KINQ
Sbjct: 142 RFRKINQ 148
>XP_005264070
          Length = 298

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FQKINQML 9
           FQ++N ML
Sbjct: 145 FQRMNHML 152
>XP_005264328
          Length = 1261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KFQKINQML 9
            +F+K+NQ L
Sbjct: 1223 EFEKMNQSL 1231
>NP_789795
          Length = 307

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FQKINQML 9
           FQ++N ML
Sbjct: 154 FQRMNHML 161
>NP_001047
          Length = 296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FQKINQML 9
           FQ++N ML
Sbjct: 143 FQRMNHML 150
>NP_742068
          Length = 1133

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KFQKINQML 9
           KF+K+N+ L
Sbjct: 445 KFRKMNKRL 453
>NP_001271230
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QKINQML 9
            QK+NQ+L
Sbjct: 1063 QKLNQVL 1069
>NP_005899
          Length = 879

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KFQKINQML 9
           K+QK+N +L
Sbjct: 92  KWQKVNLIL 100
>NP_001271231
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QKINQML 9
            QK+NQ+L
Sbjct: 1062 QKLNQVL 1068
>NP_940966
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QKINQML 9
          QKINQ++
Sbjct: 51 QKINQLV 57
>NP_061155
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QKINQML 9
            QK+NQ+L
Sbjct: 1100 QKLNQVL 1106
>NP_057097
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FQKINQM 8
           FQ+ NQM
Sbjct: 230 FQRTNQM 236
>NP_848599
          Length = 3092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QKINQML 9
          QKINQ++
Sbjct: 51 QKINQLV 57
>NP_937870
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KFQKIN 6
           K+QKIN
Sbjct: 530 KYQKIN 535
>NP_937872
          Length = 1447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    KFQKIN 6
            K+QKIN
Sbjct: 1178 KYQKIN 1183
>XP_006720621
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FQKINQM 8
           FQ+ NQM
Sbjct: 230 FQRTNQM 236
>XP_006720620
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FQKINQM 8
           FQ+ NQM
Sbjct: 230 FQRTNQM 236
>XP_006720619
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FQKINQM 8
           FQ+ NQM
Sbjct: 230 FQRTNQM 236
>XP_006720618
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FQKINQM 8
           FQ+ NQM
Sbjct: 230 FQRTNQM 236
>XP_006715810
          Length = 1105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QKINQML 9
            QK+NQ+L
Sbjct: 1081 QKLNQVL 1087
>XP_006715809
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QKINQML 9
            QK+NQ+L
Sbjct: 1118 QKLNQVL 1124
>XP_006713970
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   KFQKIN 6
           K+QKIN
Sbjct: 377 KYQKIN 382
>XP_006713968
          Length = 1447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    KFQKIN 6
            K+QKIN
Sbjct: 1178 KYQKIN 1183
>XP_006713081
          Length = 3964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QKINQML 9
          QKINQ++
Sbjct: 51 QKINQLV 57
>XP_006711246
          Length = 1101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KFQKINQML 9
           KF+K+N+ L
Sbjct: 445 KFRKMNKRL 453
>XP_005244978
          Length = 1113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KFQKINQML 9
           KF+K+N+ L
Sbjct: 445 KFRKMNKRL 453
>XP_005244977
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KFQKINQML 9
           KF+K+N+ L
Sbjct: 445 KFRKMNKRL 453
>XP_005244976
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KFQKINQML 9
           KF+K+N+ L
Sbjct: 445 KFRKMNKRL 453
>XP_005244975
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KFQKINQML 9
           KF+K+N+ L
Sbjct: 445 KFRKMNKRL 453
>NP_002917
          Length = 1376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    KFQKIN 6
            K+QKIN
Sbjct: 1178 KYQKIN 1183
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.138    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 372,109
Number of extensions: 721
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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