Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           18    1135
NP_001138390                                                           18    1135
NP_001138386                                                           18    1135
NP_001138387                                                           18    1135
NP_000132                                                              18    1135
NP_075259                                                              18    1135
NP_001138388                                                           18    1135
NP_001138391                                                           18    1135
NP_001138385                                                           18    1135
NP_075418                                                              18    1135
XP_006717776                                                           18    1135
XP_006717775                                                           18    1135
XP_006717774                                                           18    1135
XP_006717773                                                           18    1135
XP_006717772                                                           18    1135
XP_006717771                                                           18    1135
NP_001239542                                                           17    4312
NP_001239541                                                           17    4312
NP_001014972                                                           17    4312
NP_055312                                                              17    4312
XP_005264321                                                           17    4312
XP_006712053                                                           17    4312
XP_005264320                                                           17    4312
XP_006712052                                                           17    4312
XP_005264319                                                           17    4312
XP_005264318                                                           17    4312
NP_001157871                                                           16    7355
NP_001136408                                                           16    7355
NP_631918                                                              16    7355
NP_001073948                                                           16    7355
NP_001171164                                                           16    7355
NP_976221                                                              15    9605
NP_056078                                                              15    9605
NP_001161846                                                           15    9605
NP_005327                                                              15    9605
NP_001161849                                                           15    9605
NP_001167587                                                           15    9605
NP_001161848                                                           15    9605
NP_001239257                                                           15    9605
NP_055624                                                              15    9605
NP_001161847                                                           15    9605
XP_005254315                                                           15    9605
XP_005254314                                                           15    9605
XP_006720509                                                           15    9605
XP_005254313                                                           15    9605
XP_005254312                                                           15    9605
XP_006715351                                                           15    9605
XP_006715350                                                           15    9605
XP_006715349                                                           15    9605
XP_005249561                                                           15    9605
XP_006712539                                                           15    9605
XP_005247059                                                           15    9605
XP_005247058                                                           15    9605
XP_006712538                                                           15    9605
XP_005247060                                                           15    9605
XP_005247057                                                           15    9605
>NP_001138389
          Length = 705

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 393 KEAVTVAVK 401
>NP_001138390
          Length = 704

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 392 KEAVTVAVK 400
>NP_001138386
          Length = 709

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 397 KEAVTVAVK 405
>NP_001138387
          Length = 707

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 420 KEAVTVAVK 428
>NP_000132
          Length = 821

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 509 KEAVTVAVK 517
>NP_075259
          Length = 822

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 510 KEAVTVAVK 518
>NP_001138388
          Length = 706

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 394 KEAVTVAVK 402
>NP_001138391
          Length = 680

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 421 KEAVTVAVK 429
>NP_001138385
          Length = 769

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 510 KEAVTVAVK 518
>NP_075418
          Length = 732

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 420 KEAVTVAVK 428
>XP_006717776
          Length = 806

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 528 KEAVTVAVK 536
>XP_006717775
          Length = 726

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 414 KEAVTVAVK 422
>XP_006717774
          Length = 752

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 440 KEAVTVAVK 448
>XP_006717773
          Length = 807

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 529 KEAVTVAVK 537
>XP_006717772
          Length = 838

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 526 KEAVTVAVK 534
>XP_006717771
          Length = 839

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE VTVAVK
Sbjct: 527 KEAVTVAVK 535
>NP_001239542
          Length = 1957

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KETVTVAVK 9
           K  VTVAVK
Sbjct: 817 KSVVTVAVK 825
>NP_001239541
          Length = 1978

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KETVTVAVK 9
           K  VTVAVK
Sbjct: 817 KSVVTVAVK 825
>NP_001014972
          Length = 1978

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KETVTVAVK 9
           K  VTVAVK
Sbjct: 817 KSVVTVAVK 825
>NP_055312
          Length = 1978

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KETVTVAVK 9
           K  VTVAVK
Sbjct: 817 KSVVTVAVK 825
>XP_005264321
          Length = 1206

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KETVTVAVK 9
           K  VTVAVK
Sbjct: 923 KSVVTVAVK 931
>XP_006712053
          Length = 1467

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KETVTVAVK 9
           K  VTVAVK
Sbjct: 306 KSVVTVAVK 314
>XP_005264320
          Length = 1467

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KETVTVAVK 9
           K  VTVAVK
Sbjct: 306 KSVVTVAVK 314
>XP_006712052
          Length = 1467

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KETVTVAVK 9
           K  VTVAVK
Sbjct: 306 KSVVTVAVK 314
>XP_005264319
          Length = 2049

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KETVTVAVK 9
           K  VTVAVK
Sbjct: 923 KSVVTVAVK 931
>XP_005264318
          Length = 2084

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KETVTVAVK 9
           K  VTVAVK
Sbjct: 923 KSVVTVAVK 931
>NP_001157871
          Length = 793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KETVTVA 7
           KETVTV+
Sbjct: 273 KETVTVS 279
>NP_001136408
          Length = 543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE+V VAV+
Sbjct: 237 KESVVVAVR 245
>NP_631918
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           KE+V VAV+
Sbjct: 366 KESVVVAVR 374
>NP_001073948
          Length = 1731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  KETVTVAV 8
          +ETVTV+V
Sbjct: 65 QETVTVSV 72
>NP_001171164
          Length = 1705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  KETVTVAV 8
          +ETVTV+V
Sbjct: 65 QETVTVSV 72
>NP_976221
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           K+T T+AV+
Sbjct: 293 KKTTTIAVE 301
>NP_056078
          Length = 3036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KETVTV 6
            KETVTV
Sbjct: 1407 KETVTV 1412
>NP_001161846
          Length = 1063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TVTVAVK 9
           T+TVAVK
Sbjct: 697 TLTVAVK 703
>NP_005327
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           K+T T+AV+
Sbjct: 293 KKTTTIAVE 301
>NP_001161849
          Length = 1011

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TVTVAVK 9
           T+TVAVK
Sbjct: 706 TLTVAVK 712
>NP_001167587
          Length = 3037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KETVTV 6
            KETVTV
Sbjct: 1407 KETVTV 1412
>NP_001161848
          Length = 1027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TVTVAVK 9
           T+TVAVK
Sbjct: 661 TLTVAVK 667
>NP_001239257
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TVTVAVK 9
           T+TVAVK
Sbjct: 117 TLTVAVK 123
>NP_055624
          Length = 1072

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TVTVAVK 9
           T+TVAVK
Sbjct: 706 TLTVAVK 712
>NP_001161847
          Length = 1072

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TVTVAVK 9
           T+TVAVK
Sbjct: 706 TLTVAVK 712
>XP_005254315
          Length = 2576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KETVTV 6
            KETVTV
Sbjct: 1407 KETVTV 1412
>XP_005254314
          Length = 2605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KETVTV 6
            KETVTV
Sbjct: 1407 KETVTV 1412
>XP_006720509
          Length = 2646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KETVTV 6
            KETVTV
Sbjct: 1407 KETVTV 1412
>XP_005254313
          Length = 3057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KETVTV 6
            KETVTV
Sbjct: 1407 KETVTV 1412
>XP_005254312
          Length = 3058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    KETVTV 6
            KETVTV
Sbjct: 1407 KETVTV 1412
>XP_006715351
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TVTVAVK 9
           T+TVAVK
Sbjct: 554 TLTVAVK 560
>XP_006715350
          Length = 1040

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TVTVAVK 9
           T+TVAVK
Sbjct: 768 TLTVAVK 774
>XP_006715349
          Length = 1101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TVTVAVK 9
           T+TVAVK
Sbjct: 735 TLTVAVK 741
>XP_005249561
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TVTVAVK 9
           T+TVAVK
Sbjct: 768 TLTVAVK 774
>XP_006712539
          Length = 1250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           K+T T+AV+
Sbjct: 293 KKTTTIAVE 301
>XP_005247059
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           K+T T+AV+
Sbjct: 293 KKTTTIAVE 301
>XP_005247058
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           K+T T+AV+
Sbjct: 293 KKTTTIAVE 301
>XP_006712538
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           K+T T+AV+
Sbjct: 293 KKTTTIAVE 301
>XP_005247060
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           K+T T+AV+
Sbjct: 293 KKTTTIAVE 301
>XP_005247057
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KETVTVAVK 9
           K+T T+AV+
Sbjct: 293 KKTTTIAVE 301
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.112    0.254 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 277,405
Number of extensions: 297
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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