Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1935
XP_005262424                                                           18    1935
NP_055853                                                              17    3301
NP_003310                                                              16    7355
NP_597676                                                              16    7355
NP_001243779                                                           16    7355
NP_596869                                                              16    7355
NP_006793                                                              16    7355
XP_005246888                                                           16    7355
XP_006712788                                                           16    7355
XP_006712787                                                           16    7355
XP_006712786                                                           16    7355
XP_005270447                                                           16    7355
NP_001254479                                                           16    7355
NP_597681                                                              16    7355
NP_005041                                                              15    9605
XP_005268010                                                           15    9605
XP_005268011                                                           15    9605
XP_005268009                                                           15    9605
XP_005268008                                                           15    9605
XP_005268003                                                           15    9605
XP_005268006                                                           15    9605
XP_005267999                                                           15    9605
XP_005267997                                                           15    9605
XP_005267998                                                           15    9605
XP_005267996                                                           15    9605
XP_006720286                                                           15    9605
>NP_722576
          Length = 3080

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KESTSALTA 9
            KESTSAL A
Sbjct: 1380 KESTSALPA 1388
>XP_005262424
          Length = 2875

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KESTSALTA 9
            KESTSAL A
Sbjct: 1175 KESTSALPA 1183
>NP_055853
          Length = 1427

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   KESTSALT 8
           KES+SALT
Sbjct: 169 KESSSALT 176
>NP_003310
          Length = 26926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ESTSALTA 9
             EST A+TA
Sbjct: 16030 ESTGAITA 16037
>NP_597676
          Length = 27051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ESTSALTA 9
             EST A+TA
Sbjct: 16155 ESTGAITA 16162
>NP_001243779
          Length = 34350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ESTSALTA 9
             EST A+TA
Sbjct: 23454 ESTGAITA 23461
>NP_596869
          Length = 33423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ESTSALTA 9
             EST A+TA
Sbjct: 22527 ESTGAITA 22534
>NP_006793
          Length = 501

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KESTSALT 8
           KE++SALT
Sbjct: 231 KETSSALT 238
>XP_005246888
          Length = 22663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ESTSALTA 9
             EST A+TA
Sbjct: 11767 ESTGAITA 11774
>XP_006712788
          Length = 24022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ESTSALTA 9
             EST A+TA
Sbjct: 13126 ESTGAITA 13133
>XP_006712787
          Length = 33978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ESTSALTA 9
             EST A+TA
Sbjct: 23082 ESTGAITA 23089
>XP_006712786
          Length = 35484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ESTSALTA 9
             EST A+TA
Sbjct: 24588 ESTGAITA 24595
>XP_005270447
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KESTSALT 8
           KE++SALT
Sbjct: 178 KETSSALT 185
>NP_001254479
          Length = 35991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ESTSALTA 9
             EST A+TA
Sbjct: 25095 ESTGAITA 25102
>NP_597681
          Length = 27118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ESTSALTA 9
             EST A+TA
Sbjct: 16222 ESTGAITA 16229
>NP_005041
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESTSALT 8
           E+TSALT
Sbjct: 549 EATSALT 555
>XP_005268010
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESTSALT 8
           E+TSALT
Sbjct: 286 EATSALT 292
>XP_005268011
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESTSALT 8
           E+TSALT
Sbjct: 286 EATSALT 292
>XP_005268009
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESTSALT 8
           E+TSALT
Sbjct: 286 EATSALT 292
>XP_005268008
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESTSALT 8
           E+TSALT
Sbjct: 286 EATSALT 292
>XP_005268003
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESTSALT 8
           E+TSALT
Sbjct: 390 EATSALT 396
>XP_005268006
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESTSALT 8
           E+TSALT
Sbjct: 390 EATSALT 396
>XP_005267999
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESTSALT 8
           E+TSALT
Sbjct: 411 EATSALT 417
>XP_005267997
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESTSALT 8
           E+TSALT
Sbjct: 411 EATSALT 417
>XP_005267998
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESTSALT 8
           E+TSALT
Sbjct: 411 EATSALT 417
>XP_005267996
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESTSALT 8
           E+TSALT
Sbjct: 411 EATSALT 417
>XP_006720286
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ESTSALT 8
           E+TSALT
Sbjct: 462 EATSALT 468
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.278   0.0893    0.187 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 260,129
Number of extensions: 292
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)

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