Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           18    1935
NP_000242                                                              18    1935
XP_005264389                                                           18    1935
NP_037498                                                              17    3301
NP_689807                                                              16    5631
NP_001035241                                                           16    5631
NP_060870                                                              16    5631
NP_001013764                                                           16    5631
NP_059119                                                              16    5631
NP_112598                                                              16    5631
XP_005254260                                                           16    5631
XP_005254259                                                           16    5631
XP_006718945                                                           16    5631
XP_005263119                                                           16    5631
NP_001277155                                                           16    7355
NP_001277156                                                           16    7355
NP_055998                                                              16    7355
NP_008971                                                              16    7355
NP_001158136                                                           16    7355
NP_653333                                                              16    7355
XP_005258523                                                           16    7355
XP_005258522                                                           16    7355
XP_005258520                                                           16    7355
XP_005258521                                                           16    7355
XP_005258519                                                           16    7355
XP_005258518                                                           16    7355
XP_005258516                                                           16    7355
XP_006714675                                                           16    7355
XP_006714673                                                           16    7355
XP_006714672                                                           16    7355
XP_006714670                                                           16    7355
XP_006714669                                                           16    7355
XP_006714668                                                           16    7355
XP_006714667                                                           16    7355
XP_006714666                                                           16    7355
XP_005248555                                                           16    7355
XP_006714665                                                           16    7355
NP_001074006                                                           16    7355
NP_001013725                                                           15    9605
NP_001229338                                                           15    9605
NP_060786                                                              15    9605
NP_878274                                                              15    9605
NP_073588                                                              15    9605
XP_006722848                                                           15    9605
XP_005254450                                                           15    9605
XP_005254449                                                           15    9605



>NP_001245210
          Length = 868

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  LLVRQYR 9
          LLVRQYR
Sbjct: 27 LLVRQYR 33





>NP_000242
          Length = 934

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  LLVRQYR 9
          LLVRQYR
Sbjct: 93 LLVRQYR 99





>XP_005264389
          Length = 921

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  LLVRQYR 9
          LLVRQYR
Sbjct: 93 LLVRQYR 99





>NP_037498
          Length = 822

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KDLLVRQYR 9
           KDL + +YR
Sbjct: 512 KDLFINEYR 520





>NP_689807
          Length = 444

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   KDLLVRQY 8
           +D+L+R+Y
Sbjct: 251 RDILIRRY 258





>NP_001035241
          Length = 215

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  KDLLVRQYR 9
          KD L+ +YR
Sbjct: 70 KDFLIYEYR 78





>NP_060870
          Length = 215

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  KDLLVRQYR 9
          KD L+ +YR
Sbjct: 70 KDFLIYEYR 78





>NP_001013764
          Length = 1271

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KDLLVRQYR 9
           K+LL R YR
Sbjct: 901 KELLQRSYR 909





>NP_059119
          Length = 657

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KDLLVRQY 8
           KD++ RQY
Sbjct: 105 KDIMQRQY 112





>NP_112598
          Length = 5088

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KDLLVRQY 8
            KDL+VR++
Sbjct: 1669 KDLIVREH 1676






 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KDLLVRQY 8
            KDL+VR++
Sbjct: 2327 KDLIVREH 2334






 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KDLLVRQY 8
            KDL+VR++
Sbjct: 2863 KDLIVREH 2870






 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KDLLVRQY 8
            KDL+VR++
Sbjct: 3394 KDLIVREH 3401






 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KDLLVRQY 8
            KDL+VR++
Sbjct: 3928 KDLIVREH 3935






 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KDLLVRQY 8
            KDL+VR++
Sbjct: 4462 KDLIVREH 4469






 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KDLLVRQY 8
            KDL+VR++
Sbjct: 4995 KDLIVREH 5002





>XP_005254260
          Length = 370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   KDLLVRQY 8
           +D+L+R+Y
Sbjct: 177 RDILIRRY 184





>XP_005254259
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   KDLLVRQY 8
           +D+L+R+Y
Sbjct: 263 RDILIRRY 270





>XP_006718945
          Length = 215

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  KDLLVRQYR 9
          KD L+ +YR
Sbjct: 70 KDFLIYEYR 78





>XP_005263119
          Length = 657

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KDLLVRQY 8
           KD++ RQY
Sbjct: 105 KDIMQRQY 112





>NP_001277155
          Length = 2417

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2395 KDFVVRQRR 2403





>NP_001277156
          Length = 2362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2340 KDFVVRQRR 2348





>NP_055998
          Length = 2434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2412 KDFVVRQRR 2420





>NP_008971
          Length = 856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DLLVRQY 8
           D LVRQY
Sbjct: 588 DKLVRQY 594





>NP_001158136
          Length = 2623

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2601 KDFVVRQRR 2609





>NP_653333
          Length = 756

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DLLVRQY 8
           D LVRQY
Sbjct: 488 DKLVRQY 494





>XP_005258523
          Length = 756

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DLLVRQY 8
           D LVRQY
Sbjct: 488 DKLVRQY 494





>XP_005258522
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DLLVRQY 8
           D LVRQY
Sbjct: 488 DKLVRQY 494





>XP_005258520
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DLLVRQY 8
           D LVRQY
Sbjct: 488 DKLVRQY 494





>XP_005258521
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DLLVRQY 8
           D LVRQY
Sbjct: 488 DKLVRQY 494





>XP_005258519
          Length = 767

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DLLVRQY 8
           D LVRQY
Sbjct: 499 DKLVRQY 505





>XP_005258518
          Length = 777

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DLLVRQY 8
           D LVRQY
Sbjct: 499 DKLVRQY 505





>XP_005258516
          Length = 866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DLLVRQY 8
           D LVRQY
Sbjct: 588 DKLVRQY 594





>XP_006714675
          Length = 2275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2253 KDFVVRQRR 2261





>XP_006714673
          Length = 2362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2340 KDFVVRQRR 2348





>XP_006714672
          Length = 2414

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2392 KDFVVRQRR 2400





>XP_006714670
          Length = 2425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2403 KDFVVRQRR 2411





>XP_006714669
          Length = 2429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2407 KDFVVRQRR 2415





>XP_006714668
          Length = 2429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2407 KDFVVRQRR 2415





>XP_006714667
          Length = 2432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2410 KDFVVRQRR 2418





>XP_006714666
          Length = 2432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2410 KDFVVRQRR 2418





>XP_005248555
          Length = 2626

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2604 KDFVVRQRR 2612





>XP_006714665
          Length = 2651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    KDLLVRQYR 9
            KD +VRQ R
Sbjct: 2629 KDFVVRQRR 2637





>NP_001074006
          Length = 147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KDLLVRQYR 9
          KDLL  Q+R
Sbjct: 83 KDLLQTQFR 91





>NP_001013725
          Length = 1649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    DLLVRQYR 9
            DLL+ Q+R
Sbjct: 1353 DLLIPQFR 1360





>NP_001229338
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  DLLVRQYR 9
          DLLV  YR
Sbjct: 24 DLLVSTYR 31





>NP_060786
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KDLLVRQY 8
           +D+L RQY
Sbjct: 273 EDVLCRQY 280





>NP_878274
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KDLLVRQY 8
           K+L VR+Y
Sbjct: 307 KELTVREY 314





>NP_073588
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  DLLVRQYR 9
          DLLV  YR
Sbjct: 24 DLLVSTYR 31





>XP_006722848
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KDLLVRQY 8
           +D+L RQY
Sbjct: 262 EDVLCRQY 269





>XP_005254450
          Length = 1505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    DLLVRQYR 9
            DLL+ Q+R
Sbjct: 1353 DLLIPQFR 1360





>XP_005254449
          Length = 1626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    DLLVRQYR 9
            DLL+ Q+R
Sbjct: 1353 DLLIPQFR 1360





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.150    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 492,245
Number of extensions: 910
Number of successful extensions: 52
Number of sequences better than 10000.0: 46
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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