Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              21     229
XP_006714104                                                           21     229
XP_005265800                                                           21     229
XP_006714103                                                           21     229
XP_006714102                                                           21     229
XP_006714837                                                           17    4312
NP_003787                                                              16    5631
NP_001239570                                                           16    5631
XP_005259420                                                           16    5631
XP_005259419                                                           16    5631
NP_722520                                                              16    7355
NP_055845                                                              16    7355
XP_005248148                                                           16    7355
XP_005248147                                                           16    7355
XP_005248146                                                           16    7355
XP_005248145                                                           16    7355
XP_005248144                                                           16    7355
XP_005248143                                                           16    7355
XP_005248142                                                           16    7355
XP_005248141                                                           16    7355
XP_005248140                                                           16    7355
XP_005248139                                                           16    7355
NP_060396                                                              15    9605
NP_976241                                                              15    9605
NP_001269721                                                           15    9605
NP_060442                                                              15    9605
XP_006720255                                                           15    9605
XP_006720254                                                           15    9605
XP_005265090                                                           15    9605
XP_005265088                                                           15    9605
XP_005246837                                                           15    9605
XP_005246836                                                           15    9605
XP_006712758                                                           15    9605
XP_005246834                                                           15    9605
XP_005246720                                                           15    9605
XP_006712229                                                           15    9605
XP_006712228                                                           15    9605
XP_005276116                                                           15    9605
NP_001035869                                                           15    9605
NP_060559                                                              15    9605
NP_056281                                                              15    9605
>NP_006197
          Length = 1089

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KCAARQATR 9
           +CAARQATR
Sbjct: 289 ECAARQATR 297
>XP_006714104
          Length = 832

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KCAARQATR 9
           +CAARQATR
Sbjct: 314 ECAARQATR 322
>XP_005265800
          Length = 1089

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KCAARQATR 9
           +CAARQATR
Sbjct: 289 ECAARQATR 297
>XP_006714103
          Length = 1111

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KCAARQATR 9
           +CAARQATR
Sbjct: 311 ECAARQATR 319
>XP_006714102
          Length = 1114

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KCAARQATR 9
           +CAARQATR
Sbjct: 314 ECAARQATR 322
>XP_006714837
          Length = 628

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KCAARQATR 9
           KC+  QAT+
Sbjct: 600 KCSCNQATK 608
>NP_003787
          Length = 535

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KCAARQA 7
           KC+A+QA
Sbjct: 107 KCSAKQA 113
>NP_001239570
          Length = 475

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  KCAARQA 7
          KC+A+QA
Sbjct: 89 KCSAKQA 95
>XP_005259420
          Length = 493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KCAARQA 7
           KC+A+QA
Sbjct: 107 KCSAKQA 113
>XP_005259419
          Length = 517

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  KCAARQA 7
          KC+A+QA
Sbjct: 89 KCSAKQA 95
>NP_722520
          Length = 1006

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   CAARQAT 8
           CA+RQ T
Sbjct: 264 CASRQGT 270
>NP_055845
          Length = 3013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CAARQATR 9
           C++R ATR
Sbjct: 696 CSSRPATR 703
>XP_005248148
          Length = 3028

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CAARQATR 9
           C++R ATR
Sbjct: 711 CSSRPATR 718
>XP_005248147
          Length = 3028

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CAARQATR 9
           C++R ATR
Sbjct: 711 CSSRPATR 718
>XP_005248146
          Length = 3073

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CAARQATR 9
           C++R ATR
Sbjct: 803 CSSRPATR 810
>XP_005248145
          Length = 3079

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CAARQATR 9
           C++R ATR
Sbjct: 762 CSSRPATR 769
>XP_005248144
          Length = 3099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CAARQATR 9
           C++R ATR
Sbjct: 788 CSSRPATR 795
>XP_005248143
          Length = 3105

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CAARQATR 9
           C++R ATR
Sbjct: 788 CSSRPATR 795
>XP_005248142
          Length = 3114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CAARQATR 9
           C++R ATR
Sbjct: 803 CSSRPATR 810
>XP_005248141
          Length = 3119

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CAARQATR 9
           C++R ATR
Sbjct: 803 CSSRPATR 810
>XP_005248140
          Length = 3119

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CAARQATR 9
           C++R ATR
Sbjct: 803 CSSRPATR 810
>XP_005248139
          Length = 3120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   CAARQATR 9
           C++R ATR
Sbjct: 803 CSSRPATR 810
>NP_060396
          Length = 482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   CAARQA 7
           C+ARQA
Sbjct: 395 CSARQA 400
>NP_976241
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KCAARQATR 9
           +C+++QA R
Sbjct: 250 RCSSKQAKR 258
>NP_001269721
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ARQATR 9
           ARQATR
Sbjct: 402 ARQATR 407
>NP_060442
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   CAARQA 7
           C+ARQA
Sbjct: 390 CSARQA 395
>XP_006720255
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   CAARQA 7
           C+ARQA
Sbjct: 395 CSARQA 400
>XP_006720254
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   CAARQA 7
           C+ARQA
Sbjct: 390 CSARQA 395
>XP_005265090
          Length = 1510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CAARQATR 9
           C AR+A R
Sbjct: 571 CQAREAAR 578
>XP_005265088
          Length = 1694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CAARQATR 9
           C AR+A R
Sbjct: 755 CQAREAAR 762
>XP_005246837
          Length = 1277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KCAARQATR 9
           +C+++QA R
Sbjct: 250 RCSSKQAKR 258
>XP_005246836
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KCAARQATR 9
           +C+++QA R
Sbjct: 250 RCSSKQAKR 258
>XP_006712758
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KCAARQATR 9
           +C+++QA R
Sbjct: 250 RCSSKQAKR 258
>XP_005246834
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   KCAARQATR 9
           +C+++QA R
Sbjct: 250 RCSSKQAKR 258
>XP_005246720
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ARQATR 9
           ARQATR
Sbjct: 547 ARQATR 552
>XP_006712229
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ARQATR 9
           ARQATR
Sbjct: 414 ARQATR 419
>XP_006712228
          Length = 202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ARQATR 9
          ARQATR
Sbjct: 16 ARQATR 21
>XP_005276116
          Length = 75

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  ARQATR 9
          ARQATR
Sbjct: 16 ARQATR 21
>NP_001035869
          Length = 726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ARQATR 9
           ARQATR
Sbjct: 612 ARQATR 617
>NP_060559
          Length = 726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ARQATR 9
           ARQATR
Sbjct: 612 ARQATR 617
>NP_056281
          Length = 1636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   CAARQATR 9
           C AR+A R
Sbjct: 697 CQAREAAR 704
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.116    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 390,891
Number of extensions: 345
Number of successful extensions: 41
Number of sequences better than 10000.0: 41
Number of HSP's gapped: 41
Number of HSP's successfully gapped: 41
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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