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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001273171                                                           17    4312
NP_004110                                                              17    4312
NP_001511                                                              17    4312
NP_055999                                                              16    5631
NP_001137854                                                           16    5631
NP_777582                                                              16    5631
XP_006724043                                                           16    5631
XP_006720079                                                           16    5631
XP_006716590                                                           16    5631
XP_006716589                                                           16    5631
XP_006713136                                                           16    5631
NP_001139586                                                           16    5631
NP_004398                                                              16    7355
NP_001073380                                                           16    7355
NP_005202                                                              15    9605
NP_000213                                                              15    9605
NP_001087241                                                           15    9605
NP_001275634                                                           15    9605
XP_005265799                                                           15    9605
XP_005265798                                                           15    9605
XP_005265797                                                           15    9605

>NP_001273171
          Length = 2084

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    AVRGNSRL 9
            + RGNSRL
Sbjct: 1168 SARGNSRL 1175



>NP_004110
          Length = 993

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VRGNSRL 9
           VRGN+RL
Sbjct: 844 VRGNARL 850



>NP_001511
          Length = 2109

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    AVRGNSRL 9
            + RGNSRL
Sbjct: 1168 SARGNSRL 1175



>NP_055999
          Length = 1001

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KAVRGNSRL 9
          K VR NSR+
Sbjct: 24 KKVRSNSRI 32



>NP_001137854
          Length = 1127

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KAVRGNSRL 9
           K VR NSR+
Sbjct: 150 KKVRSNSRI 158



>NP_777582
          Length = 580

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KAVRGNSRL 9
           +AVRG SRL
Sbjct: 507 RAVRGWSRL 515



>XP_006724043
          Length = 1174

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KAVRGNSRL 9
            KA RG SRL
Sbjct: 1166 KAGRGGSRL 1174



>XP_006720079
          Length = 324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KAVRGN 6
           KAVRGN
Sbjct: 310 KAVRGN 315



>XP_006716590
          Length = 473

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KAVRGNSRL 9
           +AVRG SRL
Sbjct: 400 RAVRGWSRL 408



>XP_006716589
          Length = 568

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KAVRGNSRL 9
           +AVRG SRL
Sbjct: 495 RAVRGWSRL 503



>XP_006713136
          Length = 1022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KAVRGNSRL 9
          K VR NSR+
Sbjct: 45 KKVRSNSRI 53



>NP_001139586
          Length = 1110

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KAVRGNSRL 9
            KA RG SRL
Sbjct: 1102 KAGRGGSRL 1110



>NP_004398
          Length = 513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KAVRGNSRL 9
           ++ RGNSR+
Sbjct: 224 RSERGNSRM 232



>NP_001073380
          Length = 497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KAVRGNSRL 9
           ++ RGNSR+
Sbjct: 208 RSERGNSRM 216



>NP_005202
          Length = 972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VRGNSRL 9
           V+GN+RL
Sbjct: 811 VKGNARL 817



>NP_000213
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VRGNSRL 9
           V+GN+RL
Sbjct: 825 VKGNARL 831



>NP_001087241
          Length = 972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VRGNSRL 9
           V+GN+RL
Sbjct: 821 VKGNARL 827



>NP_001275634
          Length = 972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VRGNSRL 9
           V+GN+RL
Sbjct: 811 VKGNARL 817



>XP_005265799
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VRGNSRL 9
           V+GN+RL
Sbjct: 822 VKGNARL 828



>XP_005265798
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VRGNSRL 9
           V+GN+RL
Sbjct: 825 VKGNARL 831



>XP_005265797
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VRGNSRL 9
           V+GN+RL
Sbjct: 826 VKGNARL 832



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.129    0.337 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 478,433
Number of extensions: 378
Number of successful extensions: 21
Number of sequences better than 10000.0: 21
Number of HSP's gapped: 21
Number of HSP's successfully gapped: 21
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)