Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001261                                                              18    1482
XP_005271924                                                           18    1482
XP_005271923                                                           18    1482
NP_002705                                                              17    3301
XP_006726166                                                           17    3301
XP_006726165                                                           17    3301
XP_006726164                                                           17    3301
XP_006726163                                                           17    3301
XP_006726071                                                           17    3301
XP_006726070                                                           17    3301
XP_006726069                                                           17    3301
XP_006726068                                                           17    3301
XP_006725978                                                           17    3301
XP_006725977                                                           17    3301
XP_006725976                                                           17    3301
XP_006725975                                                           17    3301
XP_006725886                                                           17    3301
XP_006725885                                                           17    3301
XP_006725884                                                           17    3301
XP_006725883                                                           17    3301
XP_006725769                                                           17    3301
XP_006725768                                                           17    3301
XP_006725767                                                           17    3301
XP_006725766                                                           17    3301
XP_006725555                                                           17    3301
XP_006725554                                                           17    3301
XP_006725553                                                           17    3301
XP_006725552                                                           17    3301
XP_006715196                                                           17    3301
XP_006715195                                                           17    3301
XP_006715194                                                           17    3301
XP_006715193                                                           17    3301
NP_001177894                                                           16    5631
NP_001177893                                                           16    5631
NP_932072                                                              16    5631
NP_003444                                                              16    5631
XP_006719927                                                           16    5631
XP_005266578                                                           16    5631
XP_005266576                                                           16    5631
XP_005266575                                                           16    5631
XP_005266577                                                           16    5631
XP_005266574                                                           16    5631
NP_001186092                                                           16    7355
NP_002796                                                              16    7355
XP_006722043                                                           16    7355
NP_001035203                                                           15    9605
NP_074035                                                              15    9605
NP_001035202                                                           15    9605
NP_002465                                                              15    9605
NP_000858                                                              15    9605
NP_001254757                                                           15    9605
NP_001254756                                                           15    9605
NP_001271226                                                           15    9605
NP_060805                                                              15    9605
NP_001271227                                                           15    9605
XP_005254507                                                           15    9605
XP_005254506                                                           15    9605
XP_005254505                                                           15    9605
XP_006720635                                                           15    9605
XP_006720634                                                           15    9605
XP_005267907                                                           15    9605
XP_006720266                                                           15    9605
XP_006720265                                                           15    9605
XP_006718052                                                           15    9605
XP_006718051                                                           15    9605
XP_005246577                                                           15    9605
XP_006712545                                                           15    9605
NP_112174                                                              15    9605
NP_004564                                                              15    9605
NP_000990                                                              15    9605
NP_001030335                                                           15    9605
>NP_001261
          Length = 1710

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KATKSIKVK 9
            KA KSIKVK
Sbjct: 1340 KAMKSIKVK 1348
>XP_005271924
          Length = 1710

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KATKSIKVK 9
            KA KSIKVK
Sbjct: 1340 KAMKSIKVK 1348
>XP_005271923
          Length = 1798

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KATKSIKVK 9
            KA KSIKVK
Sbjct: 1340 KAMKSIKVK 1348
>NP_002705
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006726166
          Length = 910

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006726165
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006726164
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006726163
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006726071
          Length = 910

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006726070
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006726069
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006726068
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725978
          Length = 910

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725977
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725976
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725975
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725886
          Length = 910

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725885
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725884
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725883
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725769
          Length = 910

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725768
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725767
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725766
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725555
          Length = 910

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725554
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725553
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006725552
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006715196
          Length = 910

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006715195
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006715194
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>XP_006715193
          Length = 940

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATKSIKVK 9
           ATK IKVK
Sbjct: 272 ATKEIKVK 279
>NP_001177894
          Length = 1377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KATKSIKVK 9
            K++KS+K+K
Sbjct: 1099 KSSKSVKLK 1107
>NP_001177893
          Length = 1377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KATKSIKVK 9
            K++KS+K+K
Sbjct: 1099 KSSKSVKLK 1107
>NP_932072
          Length = 1377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KATKSIKVK 9
            K++KS+K+K
Sbjct: 1099 KSSKSVKLK 1107
>NP_003444
          Length = 1377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KATKSIKVK 9
            K++KS+K+K
Sbjct: 1099 KSSKSVKLK 1107
>XP_006719927
          Length = 1159

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KATKSIKVK 9
            K++KS+K+K
Sbjct: 1099 KSSKSVKLK 1107
>XP_005266578
          Length = 1290

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KATKSIKVK 9
            K++KS+K+K
Sbjct: 1012 KSSKSVKLK 1020
>XP_005266576
          Length = 1377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KATKSIKVK 9
            K++KS+K+K
Sbjct: 1099 KSSKSVKLK 1107
>XP_005266575
          Length = 1377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KATKSIKVK 9
            K++KS+K+K
Sbjct: 1099 KSSKSVKLK 1107
>XP_005266577
          Length = 1377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KATKSIKVK 9
            K++KS+K+K
Sbjct: 1099 KSSKSVKLK 1107
>XP_005266574
          Length = 1377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KATKSIKVK 9
            K++KS+K+K
Sbjct: 1099 KSSKSVKLK 1107
>NP_001186092
          Length = 398

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KATKSIKV 8
           +ATK+IKV
Sbjct: 276 EATKNIKV 283
>NP_002796
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KATKSIKV 8
           +ATK+IKV
Sbjct: 284 EATKNIKV 291
>XP_006722043
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KATKSIKV 8
           +ATK+IKV
Sbjct: 284 EATKNIKV 291
>NP_001035203
          Length = 1979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ATKSIKVK 9
            ATKS+K K
Sbjct: 1847 ATKSLKQK 1854
>NP_074035
          Length = 1938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ATKSIKVK 9
            ATKS+K K
Sbjct: 1840 ATKSLKQK 1847
>NP_001035202
          Length = 1945

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ATKSIKVK 9
            ATKS+K K
Sbjct: 1847 ATKSLKQK 1854
>NP_002465
          Length = 1972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ATKSIKVK 9
            ATKS+K K
Sbjct: 1840 ATKSLKQK 1847
>NP_000858
          Length = 481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KATKSIK 7
           +ATKS+K
Sbjct: 400 RATKSVK 406
>NP_001254757
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KATKSIKVK 9
           K  KS+KVK
Sbjct: 123 KLKKSLKVK 131
>NP_001254756
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KATKSIKVK 9
           K  KS+KVK
Sbjct: 123 KLKKSLKVK 131
>NP_001271226
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKSIKVK 9
           TKS+K+K
Sbjct: 824 TKSVKLK 830
>NP_060805
          Length = 927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KATKSIKVK 9
           K  KS+KVK
Sbjct: 239 KLKKSLKVK 247
>NP_001271227
          Length = 1170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKSIKVK 9
           TKS+K+K
Sbjct: 828 TKSVKLK 834
>XP_005254507
          Length = 1070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKSIKVK 9
           TKS+K+K
Sbjct: 828 TKSVKLK 834
>XP_005254506
          Length = 1123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKSIKVK 9
           TKS+K+K
Sbjct: 828 TKSVKLK 834
>XP_005254505
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKSIKVK 9
           TKS+K+K
Sbjct: 828 TKSVKLK 834
>XP_006720635
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKSIKVK 9
           TKS+K+K
Sbjct: 828 TKSVKLK 834
>XP_006720634
          Length = 1184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKSIKVK 9
           TKS+K+K
Sbjct: 828 TKSVKLK 834
>XP_005267907
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KATKSIKVK 9
           K  KS+KVK
Sbjct: 239 KLKKSLKVK 247
>XP_006720266
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KATKSIKVK 9
           K  KS+KVK
Sbjct: 123 KLKKSLKVK 131
>XP_006720265
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KATKSIKVK 9
           K  KS+KVK
Sbjct: 123 KLKKSLKVK 131
>XP_006718052
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KATKSIKV 8
           K TKS+K+
Sbjct: 300 KNTKSVKI 307
>XP_006718051
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KATKSIKV 8
           K TKS+K+
Sbjct: 300 KNTKSVKI 307
>XP_005246577
          Length = 362

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KATKSIK 7
           +ATKS+K
Sbjct: 281 RATKSVK 287
>XP_006712545
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KATKSIK 7
           +ATKS+K
Sbjct: 375 RATKSVK 381
>NP_112174
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KATKSIKV 8
           K TKS+K+
Sbjct: 300 KNTKSVKI 307
>NP_004564
          Length = 1185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKSIKVK 9
           TKS+K+K
Sbjct: 828 TKSVKLK 834
>NP_000990
          Length = 70

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  KATKSIKVK 9
          K  KS+K+K
Sbjct: 18 KDAKSVKIK 26
>NP_001030335
          Length = 70

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  KATKSIKVK 9
          K  KS+K+K
Sbjct: 18 KDAKSVKIK 26
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.110    0.244 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 275,763
Number of extensions: 391
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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