Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

• Home Page
• Cancer-specific
• Epitope Search
• Data Retrieval
• Browse Gene
• Browse Tissue
• Sequence Similarity
• Partially Personalized
• Submit a Protein
• Vaccine Target
• Proteome Data
• NGS data
• BLAST & Predict
• Fully Personalized
• Proteins Pair
• Proteome Pair
• Advanced Tools
• Epitope Mapping
• Cross Reactivity
• Important Information
• Acknowledgement
• Algorithm
• Help
• Developers
• Contact

Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004351                                                              18    1135
NP_006421                                                              17    3301
NP_001243650                                                           17    3301
NP_001092879                                                           16    5631
XP_005273924                                                           16    5631
XP_006718550                                                           16    5631
XP_006718549                                                           16    5631
NP_002069                                                              16    7355
NP_001166184                                                           16    7355
XP_005265132                                                           16    7355
XP_005265131                                                           16    7355
XP_006713173                                                           16    7355
XP_005265130                                                           16    7355
XP_005265129                                                           16    7355
XP_005265128                                                           16    7355
XP_005265127                                                           16    7355
XP_005265126                                                           16    7355
XP_005276064                                                           16    7355
NP_113609                                                              15    9605
XP_006722192                                                           15    9605

>NP_004351
          Length = 882

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KAQSVEAGL 9
           KAQ VEAGL
Sbjct: 697 KAQPVEAGL 705



>NP_006421
          Length = 539

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KAQSVEAG 8
           KAQ +EAG
Sbjct: 96  KAQDIEAG 103



>NP_001243650
          Length = 509

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KAQSVEAG 8
          KAQ +EAG
Sbjct: 66 KAQDIEAG 73



>NP_001092879
          Length = 1523

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KAQSVEAGL 9
           KAQ  EAG+
Sbjct: 973 KAQEAEAGV 981



>XP_005273924
          Length = 993

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KAQSVEAGL 9
           KAQ  EAG+
Sbjct: 443 KAQEAEAGV 451



>XP_006718550
          Length = 1063

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KAQSVEAGL 9
           KAQ  EAG+
Sbjct: 985 KAQEAEAGV 993



>XP_006718549
          Length = 1535

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KAQSVEAGL 9
           KAQ  EAG+
Sbjct: 985 KAQEAEAGV 993



>NP_002069
          Length = 2230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KAQSVEAGL 9
            KAQ VEA L
Sbjct: 2022 KAQEVEAEL 2030



>NP_001166184
          Length = 2243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KAQSVEAGL 9
            KAQ VEA L
Sbjct: 2044 KAQEVEAEL 2052



>XP_005265132
          Length = 2214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KAQSVEAGL 9
            KAQ VEA L
Sbjct: 2006 KAQEVEAEL 2014



>XP_005265131
          Length = 2245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KAQSVEAGL 9
            KAQ VEA L
Sbjct: 2044 KAQEVEAEL 2052



>XP_006713173
          Length = 2250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KAQSVEAGL 9
            KAQ VEA L
Sbjct: 2042 KAQEVEAEL 2050



>XP_005265130
          Length = 2252

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KAQSVEAGL 9
            KAQ VEA L
Sbjct: 2044 KAQEVEAEL 2052



>XP_005265129
          Length = 2269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KAQSVEAGL 9
            KAQ VEA L
Sbjct: 2061 KAQEVEAEL 2069



>XP_005265128
          Length = 2278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KAQSVEAGL 9
            KAQ VEA L
Sbjct: 2077 KAQEVEAEL 2085



>XP_005265127
          Length = 2283

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KAQSVEAGL 9
            KAQ VEA L
Sbjct: 2077 KAQEVEAEL 2085



>XP_005265126
          Length = 2285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KAQSVEAGL 9
            KAQ VEA L
Sbjct: 2077 KAQEVEAEL 2085



>XP_005276064
          Length = 379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AQSVEAG 8
           AQS+EAG
Sbjct: 291 AQSLEAG 297



>NP_113609
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   QSVEAG 8
           QSVEAG
Sbjct: 567 QSVEAG 572



>XP_006722192
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   QSVEAG 8
           QSVEAG
Sbjct: 404 QSVEAG 409



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.114    0.266 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 283,992
Number of extensions: 282
Number of successful extensions: 20
Number of sequences better than 10000.0: 20
Number of HSP's gapped: 20
Number of HSP's successfully gapped: 20
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)