Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1135
XP_006716142                                                           18    1135
XP_005250088                                                           18    1135
XP_006716141                                                           18    1135
XP_005250085                                                           18    1135
XP_006716140                                                           18    1135
XP_005250084                                                           18    1135
XP_005250083                                                           18    1135
XP_005250082                                                           18    1135
NP_008877                                                              17    4312
XP_005274250                                                           17    4312
XP_006718734                                                           17    4312
XP_006718733                                                           17    4312
XP_005274249                                                           17    4312
XP_006718732                                                           17    4312
NP_039268                                                              16    5631
XP_005275579                                                           16    5631
XP_005275418                                                           16    5631
XP_005275282                                                           16    5631
XP_005275143                                                           16    5631
XP_005274986                                                           16    5631
XP_005272840                                                           16    5631
XP_005249031                                                           16    5631
NP_003473                                                              16    7355
NP_003622                                                              16    7355
XP_006719679                                                           16    7355
XP_005269219                                                           16    7355
XP_006719678                                                           16    7355
XP_006719677                                                           16    7355
NP_004482                                                              16    7355
NP_036342                                                              15    9605
NP_001093149                                                           15    9605
NP_000433                                                              15    9605
NP_001269852                                                           15    9605
NP_060260                                                              15    9605
NP_001263190                                                           15    9605
NP_652759                                                              15    9605
NP_570613                                                              15    9605
NP_777586                                                              15    9605
NP_001185599                                                           15    9605
NP_001103132                                                           15    9605
NP_001012999                                                           15    9605
XP_005276940                                                           15    9605
XP_005276939                                                           15    9605
XP_005276938                                                           15    9605
XP_005276937                                                           15    9605
XP_006722008                                                           15    9605
XP_006722007                                                           15    9605
XP_006717286                                                           15    9605
XP_006717285                                                           15    9605
XP_006717284                                                           15    9605
XP_006717283                                                           15    9605
XP_006717282                                                           15    9605
XP_005251870                                                           15    9605
XP_006716766                                                           15    9605
XP_005251170                                                           15    9605
XP_006716765                                                           15    9605
XP_006716764                                                           15    9605
XP_006716763                                                           15    9605
XP_005251168                                                           15    9605
>NP_733751
          Length = 4911

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            KAQCMF +
Sbjct: 4490 KAQCMFFK 4497
>XP_006716142
          Length = 4927

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            KAQCMF +
Sbjct: 4506 KAQCMFFK 4513
>XP_005250088
          Length = 4928

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            KAQCMF +
Sbjct: 4507 KAQCMFFK 4514
>XP_006716141
          Length = 4959

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            KAQCMF +
Sbjct: 4538 KAQCMFFK 4545
>XP_005250085
          Length = 4979

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            KAQCMF +
Sbjct: 4562 KAQCMFFK 4569
>XP_006716140
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            KAQCMF +
Sbjct: 4561 KAQCMFFK 4568
>XP_005250084
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            KAQCMF +
Sbjct: 4561 KAQCMFFK 4568
>XP_005250083
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            KAQCMF +
Sbjct: 4561 KAQCMFFK 4568
>XP_005250082
          Length = 4983

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            KAQCMF +
Sbjct: 4562 KAQCMFFK 4569
>NP_008877
          Length = 2390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QCMFLR 8
            QC+FLR
Sbjct: 1139 QCLFLR 1144
>XP_005274250
          Length = 2390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QCMFLR 8
            QC+FLR
Sbjct: 1139 QCLFLR 1144
>XP_006718734
          Length = 2390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QCMFLR 8
            QC+FLR
Sbjct: 1139 QCLFLR 1144
>XP_006718733
          Length = 2390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QCMFLR 8
            QC+FLR
Sbjct: 1139 QCLFLR 1144
>XP_005274249
          Length = 2390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QCMFLR 8
            QC+FLR
Sbjct: 1139 QCLFLR 1144
>XP_006718732
          Length = 2397

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QCMFLR 8
            QC+FLR
Sbjct: 1146 QCLFLR 1151
>NP_039268
          Length = 285

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A C+FLR
Sbjct: 218 ADCLFLR 224
>XP_005275579
          Length = 285

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A C+FLR
Sbjct: 218 ADCLFLR 224
>XP_005275418
          Length = 285

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A C+FLR
Sbjct: 218 ADCLFLR 224
>XP_005275282
          Length = 285

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A C+FLR
Sbjct: 218 ADCLFLR 224
>XP_005275143
          Length = 285

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A C+FLR
Sbjct: 218 ADCLFLR 224
>XP_005274986
          Length = 285

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A C+FLR
Sbjct: 218 ADCLFLR 224
>XP_005272840
          Length = 285

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A C+FLR
Sbjct: 218 ADCLFLR 224
>XP_005249031
          Length = 285

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A C+FLR
Sbjct: 218 ADCLFLR 224
>NP_003473
          Length = 5537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            +A+CMF +
Sbjct: 5120 RAKCMFFK 5127
>NP_003622
          Length = 976

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KAQCMFLR 8
           KA C FLR
Sbjct: 847 KAYCGFLR 854
>XP_006719679
          Length = 5536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            +A+CMF +
Sbjct: 5119 RAKCMFFK 5126
>XP_005269219
          Length = 5537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            +A+CMF +
Sbjct: 5120 RAKCMFFK 5127
>XP_006719678
          Length = 5539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            +A+CMF +
Sbjct: 5122 RAKCMFFK 5129
>XP_006719677
          Length = 5540

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1    KAQCMFLR 8
            +A+CMF +
Sbjct: 5123 RAKCMFFK 5130
>NP_004482
          Length = 1499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KAQCMFL 7
           K QC+FL
Sbjct: 727 KLQCVFL 733
>NP_036342
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3   QCMFLR 8
           QC+FL+
Sbjct: 354 QCLFLK 359
>NP_001093149
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3   QCMFLR 8
           QC+FL+
Sbjct: 354 QCLFLK 359
>NP_000433
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A+C FLR
Sbjct: 620 AKCYFLR 626
>NP_001269852
          Length = 1088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   KAQCMF 6
           KA+C+F
Sbjct: 529 KAECLF 534
>NP_060260
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   KAQCMF 6
           KA+C+F
Sbjct: 527 KAECLF 532
>NP_001263190
          Length = 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   KAQCMF 6
           KA+C+F
Sbjct: 358 KAECLF 363
>NP_652759
          Length = 1198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   KAQCMF 6
           KA+C+F
Sbjct: 639 KAECLF 644
>NP_570613
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   KAQCMF 6
           KA+C+F
Sbjct: 358 KAECLF 363
>NP_777586
          Length = 148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3 QCMFLR 8
         QC FLR
Sbjct: 3 QCCFLR 8
>NP_001185599
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 3 QCMFLR 8
         QC FLR
Sbjct: 3 QCCFLR 8
>NP_001103132
          Length = 4284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   AQCMFLR 8
           A+C++LR
Sbjct: 946 ARCLYLR 952
>NP_001012999
          Length = 967

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   QCMFLRT 9
           +C FLRT
Sbjct: 383 ECGFLRT 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   QCMFLRT 9
           +C FLRT
Sbjct: 540 ECGFLRT 546
>XP_005276940
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A+C FLR
Sbjct: 620 AKCYFLR 626
>XP_005276939
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A+C FLR
Sbjct: 620 AKCYFLR 626
>XP_005276938
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A+C FLR
Sbjct: 620 AKCYFLR 626
>XP_005276937
          Length = 727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A+C FLR
Sbjct: 620 AKCYFLR 626
>XP_006722008
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A+C FLR
Sbjct: 620 AKCYFLR 626
>XP_006722007
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   AQCMFLR 8
           A+C FLR
Sbjct: 620 AKCYFLR 626
>XP_006717286
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   KAQCMF 6
           KA+C+F
Sbjct: 535 KAECLF 540
>XP_006717285
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   KAQCMF 6
           KA+C+F
Sbjct: 265 KAECLF 270
>XP_006717284
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   KAQCMF 6
           KA+C+F
Sbjct: 402 KAECLF 407
>XP_006717283
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   KAQCMF 6
           KA+C+F
Sbjct: 527 KAECLF 532
>XP_006717282
          Length = 1094

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   KAQCMF 6
           KA+C+F
Sbjct: 535 KAECLF 540
>XP_005251870
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3   QCMFLR 8
           QC+FL+
Sbjct: 354 QCLFLK 359
>XP_006716766
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KAQCMFL 7
           KA C+FL
Sbjct: 488 KATCVFL 494
>XP_005251170
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KAQCMFL 7
           KA C+FL
Sbjct: 505 KATCVFL 511
>XP_006716765
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KAQCMFL 7
           KA C+FL
Sbjct: 553 KATCVFL 559
>XP_006716764
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KAQCMFL 7
           KA C+FL
Sbjct: 566 KATCVFL 572
>XP_006716763
          Length = 867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KAQCMFL 7
           KA C+FL
Sbjct: 569 KATCVFL 575
>XP_005251168
          Length = 868

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   KAQCMFL 7
           KA C+FL
Sbjct: 570 KATCVFL 576
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.346    0.136    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 506,250
Number of extensions: 568
Number of successful extensions: 61
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.9 bits)
S2: 28 (15.4 bits)

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