Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001121619                                                           18    1135
NP_000258                                                              18    1135
NP_001035957                                                           18    1135
XP_006721991                                                           18    1135
XP_006721990                                                           18    1135
XP_006721989                                                           18    1135
XP_005258041                                                           18    1135
XP_006721988                                                           18    1135
XP_006721987                                                           18    1135
XP_006721986                                                           18    1135
XP_005258040                                                           18    1135
XP_006721985                                                           18    1135
NP_000676                                                              16    7355
NP_033611                                                              16    7355
NP_114438                                                              16    7355
NP_004826                                                              16    7355
NP_114038                                                              16    7355
NP_001159635                                                           16    7355
NP_001159632                                                           16    7355
NP_001159634                                                           16    7355
NP_001159633                                                           16    7355
NP_005862                                                              16    7355
XP_005269439                                                           16    7355
XP_006716111                                                           16    7355
XP_006716110                                                           16    7355
XP_005250542                                                           16    7355
XP_006716109                                                           16    7355
NP_060120                                                              16    7355
NP_001003811                                                           15    9605
NP_112566                                                              15    9605
>NP_001121619
          Length = 593

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKK AQL
Sbjct: 202 KALKKVAQL 210
>NP_000258
          Length = 2818

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKK AQL
Sbjct: 202 KALKKVAQL 210
>NP_001035957
          Length = 2839

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKK AQL
Sbjct: 202 KALKKVAQL 210
>XP_006721991
          Length = 1632

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKK AQL
Sbjct: 202 KALKKVAQL 210
>XP_006721990
          Length = 2823

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKK AQL
Sbjct: 202 KALKKVAQL 210
>XP_006721989
          Length = 2823

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKK AQL
Sbjct: 202 KALKKVAQL 210
>XP_005258041
          Length = 2836

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKK AQL
Sbjct: 202 KALKKVAQL 210
>XP_006721988
          Length = 2846

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKK AQL
Sbjct: 202 KALKKVAQL 210
>XP_006721987
          Length = 2849

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKK AQL
Sbjct: 202 KALKKVAQL 210
>XP_006721986
          Length = 2854

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKK AQL
Sbjct: 189 KALKKVAQL 197
>XP_005258040
          Length = 2857

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKK AQL
Sbjct: 202 KALKKVAQL 210
>XP_006721985
          Length = 2867

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKK AQL
Sbjct: 202 KALKKVAQL 210
>NP_000676
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKKA ++
Sbjct: 220 KALKKAYEI 228
>NP_033611
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKKA ++
Sbjct: 220 KALKKAYEI 228
>NP_114438
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKKA ++
Sbjct: 249 KALKKAYEI 257
>NP_004826
          Length = 394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKKA ++
Sbjct: 255 KALKKAYEI 263
>NP_114038
          Length = 394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKKA ++
Sbjct: 255 KALKKAYEI 263
>NP_001159635
          Length = 1090

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KALKKAAQL 9
           KALK  AQL
Sbjct: 881 KALKTRAQL 889
>NP_001159632
          Length = 1374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KALKKAAQL 9
           KALK  AQL
Sbjct: 903 KALKTRAQL 911
>NP_001159634
          Length = 1253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KALKKAAQL 9
           KALK  AQL
Sbjct: 881 KALKTRAQL 889
>NP_001159633
          Length = 1296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KALKKAAQL 9
           KALK  AQL
Sbjct: 881 KALKTRAQL 889
>NP_005862
          Length = 238

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKKA ++
Sbjct: 156 KALKKAQRI 164
>XP_005269439
          Length = 199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KALKKAAQL 9
           KALKKA ++
Sbjct: 117 KALKKAQRI 125
>XP_006716111
          Length = 701

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KALKKAAQL 9
           KALK  AQL
Sbjct: 230 KALKTRAQL 238
>XP_006716110
          Length = 1141

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KALKKAAQL 9
           KALK  AQL
Sbjct: 924 KALKTRAQL 932
>XP_005250542
          Length = 1357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KALKKAAQL 9
           KALK  AQL
Sbjct: 924 KALKTRAQL 932
>XP_006716109
          Length = 1365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KALKKAAQL 9
           KALK  AQL
Sbjct: 924 KALKTRAQL 932
>NP_060120
          Length = 1098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KALKKAAQL 9
           KALK  AQL
Sbjct: 881 KALKTRAQL 889
>NP_001003811
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KALKKAAQL 9
           KALKKA  L
Sbjct: 794 KALKKALLL 802
>NP_112566
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KALKKAAQL 9
           KALKKA  L
Sbjct: 779 KALKKALLL 787
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.116    0.260 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 250,911
Number of extensions: 272
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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