Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           20     390
NP_001257437                                                           20     390
NP_006281                                                              20     390
XP_005267176                                                           20     390
NP_057692                                                              19     869
NP_004509                                                              17    4312
NP_742106                                                              17    4312
NP_742105                                                              17    4312
NP_742104                                                              17    4312
NP_742107                                                              17    4312
XP_006723855                                                           17    4312
XP_006723854                                                           17    4312
XP_006723853                                                           17    4312
XP_006723852                                                           17    4312
XP_006723851                                                           17    4312
XP_006723850                                                           17    4312
NP_689594                                                              16    5631
XP_006712319                                                           16    5631
NP_001186073                                                           16    5631
XP_005252490                                                           16    7355
XP_005252488                                                           16    7355
NP_001177957                                                           15    9605
NP_036602                                                              15    9605
NP_065866                                                              15    9605
NP_116586                                                              15    9605
NP_057526                                                              15    9605
NP_001185470                                                           15    9605
NP_001035548                                                           15    9605
NP_258428                                                              15    9605
NP_004288                                                              15    9605
NP_001193940                                                           15    9605
NP_835471                                                              15    9605
NP_694984                                                              15    9605
NP_001238920                                                           15    9605
NP_056979                                                              15    9605
NP_036530                                                              15    9605
NP_001182662                                                           15    9605
NP_001129109                                                           15    9605
NP_001129108                                                           15    9605
NP_671693                                                              15    9605
NP_001833                                                              15    9605
NP_003548                                                              15    9605
NP_001238919                                                           15    9605
NP_001238918                                                           15    9605
XP_006724701                                                           15    9605
XP_005262172                                                           15    9605
XP_005262170                                                           15    9605
XP_006722775                                                           15    9605
XP_005259580                                                           15    9605
XP_006716783                                                           15    9605
XP_005251420                                                           15    9605
XP_005251419                                                           15    9605
XP_006715974                                                           15    9605
XP_005249216                                                           15    9605
XP_005272073                                                           15    9605
XP_005272072                                                           15    9605
XP_006713692                                                           15    9605
XP_006713691                                                           15    9605
XP_006713690                                                           15    9605
XP_006713689                                                           15    9605
XP_006713688                                                           15    9605
XP_006713687                                                           15    9605
XP_006711631                                                           15    9605
XP_006711630                                                           15    9605
XP_006711629                                                           15    9605
XP_006711628                                                           15    9605
XP_005245589                                                           15    9605
XP_005245588                                                           15    9605
XP_005245587                                                           15    9605
XP_005245586                                                           15    9605
XP_005245585                                                           15    9605
XP_005245584                                                           15    9605
XP_006711627                                                           15    9605
XP_005245583                                                           15    9605
XP_005245582                                                           15    9605
XP_006711626                                                           15    9605
NP_001129110                                                           15    9605
>NP_001257436
          Length = 790

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KALFSTIKE 9
           KALFST+KE
Sbjct: 124 KALFSTLKE 132
>NP_001257437
          Length = 790

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KALFSTIKE 9
           KALFST+KE
Sbjct: 124 KALFSTLKE 132
>NP_006281
          Length = 790

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KALFSTIKE 9
           KALFST+KE
Sbjct: 124 KALFSTLKE 132
>XP_005267176
          Length = 790

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KALFSTIKE 9
           KALFST+KE
Sbjct: 124 KALFSTLKE 132
>NP_057692
          Length = 453

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   KALFSTIKE 9
           KALF+T+KE
Sbjct: 109 KALFNTLKE 117
>NP_004509
          Length = 844

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALFSTIKE 9
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>NP_742106
          Length = 841

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALFSTIKE 9
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>NP_742105
          Length = 872

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALFSTIKE 9
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>NP_742104
          Length = 854

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALFSTIKE 9
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>NP_742107
          Length = 393

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALFSTIKE 9
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>XP_006723855
          Length = 856

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALFSTIKE 9
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>XP_006723854
          Length = 858

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALFSTIKE 9
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>XP_006723853
          Length = 868

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALFSTIKE 9
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>XP_006723852
          Length = 876

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALFSTIKE 9
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>XP_006723851
          Length = 885

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALFSTIKE 9
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>XP_006723850
          Length = 886

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALFSTIKE 9
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>NP_689594
          Length = 3549

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KALFSTIKE 9
            K+ FS++KE
Sbjct: 2924 KSFFSSVKE 2932
>XP_006712319
          Length = 3308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KALFSTIKE 9
            K+ FS++KE
Sbjct: 2683 KSFFSSVKE 2691
>NP_001186073
          Length = 3327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    KALFSTIKE 9
            K+ FS++KE
Sbjct: 2702 KSFFSSVKE 2710
>XP_005252490
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ALFSTIKE 9
          +LF T+KE
Sbjct: 40 SLFDTVKE 47
>XP_005252488
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ALFSTIKE 9
          +LF T+KE
Sbjct: 40 SLFDTVKE 47
>NP_001177957
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LFSTIKE 9
           L+ST+KE
Sbjct: 423 LYSTLKE 429
>NP_036602
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LFSTIKE 9
           L+ST+KE
Sbjct: 423 LYSTLKE 429
>NP_065866
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FSTIKE 9
           FST+KE
Sbjct: 360 FSTVKE 365
>NP_116586
          Length = 1040

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FSTIKE 9
           FST+KE
Sbjct: 360 FSTVKE 365
>NP_057526
          Length = 948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           K  FS++KE
Sbjct: 892 KGFFSSLKE 900
>NP_001185470
          Length = 941

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           K  FS++KE
Sbjct: 892 KGFFSSLKE 900
>NP_001035548
          Length = 941

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           K  FS++KE
Sbjct: 892 KGFFSSLKE 900
>NP_258428
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KALF T+ E
Sbjct: 424 KALFGTMVE 432
>NP_004288
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KALFSTI 7
           KALF TI
Sbjct: 248 KALFKTI 254
>NP_001193940
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFSTIK 8
           LFSTIK
Sbjct: 171 LFSTIK 176
>NP_835471
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  KALFST 6
          KALFST
Sbjct: 81 KALFST 86
>NP_694984
          Length = 1802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    FSTIKE 9
            FST+KE
Sbjct: 1372 FSTVKE 1377
>NP_001238920
          Length = 209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+  +KE
Sbjct: 108 KALYEALKE 116
>NP_056979
          Length = 209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+  +KE
Sbjct: 108 KALYEALKE 116
>NP_036530
          Length = 668

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 351 KALYSTAME 359
>NP_001182662
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 351 KALYSTAME 359
>NP_001129109
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 344 KALYSTAME 352
>NP_001129108
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 345 KALYSTAME 353
>NP_671693
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFSTIK 8
           LFSTIK
Sbjct: 171 LFSTIK 176
>NP_001833
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFSTIK 8
           LFSTIK
Sbjct: 171 LFSTIK 176
>NP_003548
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 344 KALYSTAME 352
>NP_001238919
          Length = 209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+  +KE
Sbjct: 108 KALYEALKE 116
>NP_001238918
          Length = 209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+  +KE
Sbjct: 108 KALYEALKE 116
>XP_006724701
          Length = 1398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FSTIKE 9
           FST+KE
Sbjct: 968 FSTVKE 973
>XP_005262172
          Length = 1631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    FSTIKE 9
            FST+KE
Sbjct: 1201 FSTVKE 1206
>XP_005262170
          Length = 1752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    FSTIKE 9
            FST+KE
Sbjct: 1322 FSTVKE 1327
>XP_006722775
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 351 KALYSTAME 359
>XP_005259580
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 351 KALYSTAME 359
>XP_006716783
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFSTIK 8
           LFSTIK
Sbjct: 171 LFSTIK 176
>XP_005251420
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFSTIK 8
           LFSTIK
Sbjct: 171 LFSTIK 176
>XP_005251419
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LFSTIK 8
           LFSTIK
Sbjct: 171 LFSTIK 176
>XP_006715974
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LFSTIKE 9
           L+ST+KE
Sbjct: 375 LYSTLKE 381
>XP_005249216
          Length = 209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+  +KE
Sbjct: 108 KALYEALKE 116
>XP_005272073
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           K  FS++KE
Sbjct: 892 KGFFSSLKE 900
>XP_005272072
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           K  FS++KE
Sbjct: 892 KGFFSSLKE 900
>XP_006713692
          Length = 252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KALFST 6
           KALFST
Sbjct: 118 KALFST 123
>XP_006713691
          Length = 252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KALFST 6
           KALFST
Sbjct: 118 KALFST 123
>XP_006713690
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KALFST 6
           KALFST
Sbjct: 212 KALFST 217
>XP_006713689
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KALFST 6
           KALFST
Sbjct: 212 KALFST 217
>XP_006713688
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KALFST 6
           KALFST
Sbjct: 212 KALFST 217
>XP_006713687
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KALFST 6
           KALFST
Sbjct: 212 KALFST 217
>XP_006711631
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 321 KALYSTAME 329
>XP_006711630
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 321 KALYSTAME 329
>XP_006711629
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 321 KALYSTAME 329
>XP_006711628
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 325 KALYSTAME 333
>XP_005245589
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 337 KALYSTAME 345
>XP_005245588
          Length = 550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 345 KALYSTAME 353
>XP_005245587
          Length = 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 349 KALYSTAME 357
>XP_005245586
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 354 KALYSTAME 362
>XP_005245585
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 355 KALYSTAME 363
>XP_005245584
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 356 KALYSTAME 364
>XP_006711627
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 357 KALYSTAME 365
>XP_005245583
          Length = 571

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 366 KALYSTAME 374
>XP_005245582
          Length = 572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 367 KALYSTAME 375
>XP_006711626
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 369 KALYSTAME 377
>NP_001129110
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KALFSTIKE 9
           KAL+ST  E
Sbjct: 357 KALYSTAME 365
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.127    0.306 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 369,393
Number of extensions: 712
Number of successful extensions: 77
Number of sequences better than 10000.0: 77
Number of HSP's gapped: 77
Number of HSP's successfully gapped: 77
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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