Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              18    1482
XP_006715292                                                           18    1482
NP_055873                                                              17    4312
NP_550434                                                              17    4312
NP_001172                                                              17    4312
NP_550436                                                              17    4312
NP_001188281                                                           17    4312
XP_005256705                                                           17    4312
XP_006721589                                                           17    4312
XP_006721588                                                           17    4312
XP_006721587                                                           17    4312
XP_006721586                                                           17    4312
XP_005256702                                                           17    4312
XP_006721585                                                           17    4312
XP_006719854                                                           17    4312
XP_006719853                                                           17    4312
NP_550435                                                              17    4312
NP_000154                                                              16    5631
NP_001229329                                                           16    5631
NP_001229335                                                           16    5631
NP_001229332                                                           16    5631
NP_001229333                                                           16    5631
NP_001229330                                                           16    5631
NP_001229331                                                           16    5631
NP_001229389                                                           16    5631
NP_001229334                                                           16    5631
NP_001229328                                                           16    5631
XP_005248345                                                           16    5631
NP_001122074                                                           16    7355
NP_005730                                                              16    7355
NP_002239                                                              16    7355
NP_006382                                                              16    7355
NP_573403                                                              16    7355
NP_006381                                                              16    7355
NP_877496                                                              16    7355
XP_005260559                                                           16    7355
XP_005260558                                                           16    7355
XP_006723918                                                           16    7355
XP_005260557                                                           16    7355
XP_005260556                                                           16    7355
XP_005260555                                                           16    7355
XP_005260554                                                           16    7355
XP_006723917                                                           16    7355
XP_005260553                                                           16    7355
XP_005259964                                                           16    7355
XP_005259963                                                           16    7355
XP_005259962                                                           16    7355
XP_005254171                                                           16    7355
NP_001177924                                                           16    7355
NP_001167579                                                           16    7355
NP_077719                                                              15    9605
NP_001129476                                                           15    9605
NP_001116203                                                           15    9605
NP_056056                                                              15    9605
NP_542397                                                              15    9605
NP_001008726                                                           15    9605
NP_001245201                                                           15    9605
XP_005261319                                                           15    9605
XP_006724151                                                           15    9605
XP_006724150                                                           15    9605
XP_006724149                                                           15    9605
XP_006724148                                                           15    9605
XP_006724147                                                           15    9605
XP_006724146                                                           15    9605
XP_006724145                                                           15    9605
XP_006724144                                                           15    9605
XP_005270959                                                           15    9605
XP_005270958                                                           15    9605
XP_006710730                                                           15    9605
>NP_115927
          Length = 1321

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KADTDALLS 9
           KA TDALLS
Sbjct: 312 KAGTDALLS 320
>XP_006715292
          Length = 759

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KADTDALLS 9
           KA TDALLS
Sbjct: 299 KAGTDALLS 307
>NP_055873
          Length = 1905

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ADTDALLS 9
            +DTDALL+
Sbjct: 1485 SDTDALLA 1492
>NP_550434
          Length = 311

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KADTDALL 8
           KAD DALL
Sbjct: 140 KADHDALL 147
>NP_001172
          Length = 311

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KADTDALL 8
           KAD DALL
Sbjct: 140 KADHDALL 147
>NP_550436
          Length = 292

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KADTDALL 8
           KAD DALL
Sbjct: 121 KADHDALL 128
>NP_001188281
          Length = 306

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KADTDALL 8
           KAD DALL
Sbjct: 135 KADHDALL 142
>XP_005256705
          Length = 287

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KADTDALL 8
           KAD DALL
Sbjct: 116 KADHDALL 123
>XP_006721589
          Length = 287

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KADTDALL 8
           KAD DALL
Sbjct: 116 KADHDALL 123
>XP_006721588
          Length = 306

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KADTDALL 8
           KAD DALL
Sbjct: 135 KADHDALL 142
>XP_006721587
          Length = 351

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KADTDALL 8
           KAD DALL
Sbjct: 180 KADHDALL 187
>XP_006721586
          Length = 390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KADTDALL 8
           KAD DALL
Sbjct: 219 KADHDALL 226
>XP_005256702
          Length = 398

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KADTDALL 8
           KAD DALL
Sbjct: 227 KADHDALL 234
>XP_006721585
          Length = 409

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KADTDALL 8
           KAD DALL
Sbjct: 238 KADHDALL 245
>XP_006719854
          Length = 1550

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ADTDALLS 9
            +DTDALL+
Sbjct: 1130 SDTDALLA 1137
>XP_006719853
          Length = 1809

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ADTDALLS 9
            +DTDALL+
Sbjct: 1389 SDTDALLA 1396
>NP_550435
          Length = 287

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KADTDALL 8
           KAD DALL
Sbjct: 116 KADHDALL 123
>NP_000154
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KADTDALLS 9
           ++DTD LLS
Sbjct: 359 ESDTDRLLS 367
>NP_001229329
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KADTDALLS 9
           ++DTD LLS
Sbjct: 359 ESDTDRLLS 367
>NP_001229335
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KADTDALLS 9
           ++DTD LLS
Sbjct: 359 ESDTDRLLS 367
>NP_001229332
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KADTDALLS 9
           ++DTD LLS
Sbjct: 359 ESDTDRLLS 367
>NP_001229333
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KADTDALLS 9
           ++DTD LLS
Sbjct: 359 ESDTDRLLS 367
>NP_001229330
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KADTDALLS 9
           ++DTD LLS
Sbjct: 359 ESDTDRLLS 367
>NP_001229331
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KADTDALLS 9
           ++DTD LLS
Sbjct: 359 ESDTDRLLS 367
>NP_001229389
          Length = 616

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KADTDALLS 9
           ++DTD LLS
Sbjct: 337 ESDTDRLLS 345
>NP_001229334
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KADTDALLS 9
           ++DTD LLS
Sbjct: 359 ESDTDRLLS 367
>NP_001229328
          Length = 645

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KADTDALLS 9
           ++DTD LLS
Sbjct: 366 ESDTDRLLS 374
>XP_005248345
          Length = 616

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KADTDALLS 9
           ++DTD LLS
Sbjct: 337 ESDTDRLLS 345
>NP_001122074
          Length = 762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KADTDAL 7
           KAD DAL
Sbjct: 724 KADNDAL 730
>NP_005730
          Length = 797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KADTDAL 7
           KAD DAL
Sbjct: 759 KADNDAL 765
>NP_002239
          Length = 543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           +AD D LLS
Sbjct: 223 EADVDVLLS 231
>NP_006382
          Length = 1038

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   DTDALLS 9
           DTD LLS
Sbjct: 704 DTDTLLS 710
>NP_573403
          Length = 720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           K+D D LLS
Sbjct: 676 KSDLDTLLS 684
>NP_006381
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   DTDALLS 9
           DTD LLS
Sbjct: 704 DTDTLLS 710
>NP_877496
          Length = 720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           K+D D LLS
Sbjct: 676 KSDLDTLLS 684
>XP_005260559
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           K+D D LLS
Sbjct: 493 KSDLDTLLS 501
>XP_005260558
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           K+D D LLS
Sbjct: 493 KSDLDTLLS 501
>XP_006723918
          Length = 632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           K+D D LLS
Sbjct: 588 KSDLDTLLS 596
>XP_005260557
          Length = 632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           K+D D LLS
Sbjct: 588 KSDLDTLLS 596
>XP_005260556
          Length = 632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           K+D D LLS
Sbjct: 588 KSDLDTLLS 596
>XP_005260555
          Length = 632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           K+D D LLS
Sbjct: 588 KSDLDTLLS 596
>XP_005260554
          Length = 632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           K+D D LLS
Sbjct: 588 KSDLDTLLS 596
>XP_006723917
          Length = 720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           K+D D LLS
Sbjct: 676 KSDLDTLLS 684
>XP_005260553
          Length = 720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           K+D D LLS
Sbjct: 676 KSDLDTLLS 684
>XP_005259964
          Length = 623

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           +AD D LLS
Sbjct: 306 EADVDVLLS 314
>XP_005259963
          Length = 626

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           +AD D LLS
Sbjct: 306 EADVDVLLS 314
>XP_005259962
          Length = 629

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           +AD D LLS
Sbjct: 306 EADVDVLLS 314
>XP_005254171
          Length = 746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KADTDAL 7
           KAD DAL
Sbjct: 708 KADNDAL 714
>NP_001177924
          Length = 832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   DTDALLS 9
           DTD LLS
Sbjct: 499 DTDTLLS 505
>NP_001167579
          Length = 979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KADTDALLS 9
           K +TD LLS
Sbjct: 748 KLETDTLLS 756
>NP_077719
          Length = 2471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KADTDALLS 9
            KA+ +ALLS
Sbjct: 1770 KAEDEALLS 1778
>NP_001129476
          Length = 1073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADTDALLS 9
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>NP_001116203
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADTDALLS 9
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>NP_056056
          Length = 2002

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADTDALLS 9
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>NP_542397
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KADTDALL 8
           K D DALL
Sbjct: 136 KVDDDALL 143
>NP_001008726
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KADTDALL 8
           K D DALL
Sbjct: 136 KVDDDALL 143
>NP_001245201
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   KADTDALL 8
           K D DALL
Sbjct: 136 KVDDDALL 143
>XP_005261319
          Length = 2002

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADTDALLS 9
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724151
          Length = 2063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADTDALLS 9
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724150
          Length = 2154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADTDALLS 9
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724149
          Length = 2168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADTDALLS 9
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724148
          Length = 2176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADTDALLS 9
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724147
          Length = 2187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADTDALLS 9
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724146
          Length = 2193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADTDALLS 9
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724145
          Length = 2210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADTDALLS 9
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724144
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADTDALLS 9
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_005270959
          Length = 2432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KADTDALLS 9
            KA+ +ALLS
Sbjct: 1731 KAEDEALLS 1739
>XP_005270958
          Length = 2432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KADTDALLS 9
            KA+ +ALLS
Sbjct: 1731 KAEDEALLS 1739
>XP_006710730
          Length = 2432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KADTDALLS 9
            KA+ +ALLS
Sbjct: 1731 KAEDEALLS 1739
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.118    0.287 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 510,531
Number of extensions: 822
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package