Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              17    2528
XP_005271621                                                           17    2528
XP_006718907                                                           17    2528
XP_006718906                                                           17    2528
XP_005271619                                                           17    2528
XP_005271618                                                           17    2528
NP_000284                                                              17    3301
NP_001027005                                                           17    3301
XP_005256041                                                           17    3301
XP_005256040                                                           17    3301
NP_006717                                                              16    7355
NP_056493                                                              16    7355
NP_001186211                                                           16    7355
XP_006719869                                                           16    7355
XP_006719868                                                           16    7355
XP_005266409                                                           16    7355
XP_005266407                                                           16    7355
XP_005266403                                                           16    7355
XP_006719867                                                           16    7355
XP_006719866                                                           16    7355
XP_005266405                                                           16    7355
XP_005266404                                                           16    7355
XP_005263433                                                           16    7355
XP_005263432                                                           16    7355
XP_005263431                                                           16    7355
XP_006714492                                                           16    7355
XP_005263430                                                           16    7355
XP_005263429                                                           16    7355
NP_001005490                                                           15    9605



>NP_000042
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IVVELLMML 9
            IVVELLM L
Sbjct: 1343 IVVELLMTL 1351





>XP_005271621
          Length = 2708

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IVVELLMML 9
            IVVELLM L
Sbjct: 995  IVVELLMTL 1003





>XP_006718907
          Length = 3050

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IVVELLMML 9
            IVVELLM L
Sbjct: 1337 IVVELLMTL 1345





>XP_006718906
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IVVELLMML 9
            IVVELLM L
Sbjct: 1343 IVVELLMTL 1351





>XP_005271619
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IVVELLMML 9
            IVVELLM L
Sbjct: 1343 IVVELLMTL 1351





>XP_005271618
          Length = 3056

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IVVELLMML 9
            IVVELLM L
Sbjct: 1343 IVVELLMTL 1351





>NP_000284
          Length = 1093

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    IVVELLMML 9
            IVVELLM++
Sbjct: 998  IVVELLMVV 1006





>NP_001027005
          Length = 1086

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IVVELLMML 9
           IVVELLM++
Sbjct: 991 IVVELLMVV 999





>XP_005256041
          Length = 1086

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IVVELLMML 9
           IVVELLM++
Sbjct: 991 IVVELLMVV 999





>XP_005256040
          Length = 1093

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    IVVELLMML 9
            IVVELLM++
Sbjct: 998  IVVELLMVV 1006





>NP_006717
          Length = 2863

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1850 VVELVMLL 1857





>NP_056493
          Length = 2946

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1936 VVELVMLL 1943





>NP_001186211
          Length = 2851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1850 VVELVMLL 1857





>XP_006719869
          Length = 2943

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1933 VVELVMLL 1940





>XP_006719868
          Length = 2938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1933 VVELVMLL 1940





>XP_005266409
          Length = 1430

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VVELLMML 9
           VVEL+M+L
Sbjct: 399 VVELVMLL 406





>XP_005266407
          Length = 2641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1610 VVELVMLL 1617





>XP_005266403
          Length = 2941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1936 VVELVMLL 1943





>XP_006719867
          Length = 2961

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1930 VVELVMLL 1937





>XP_006719866
          Length = 2962

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1936 VVELVMLL 1943





>XP_005266405
          Length = 2964

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1933 VVELVMLL 1940





>XP_005266404
          Length = 2967

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1936 VVELVMLL 1943





>XP_005263433
          Length = 2832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1814 VVELVMLL 1821





>XP_005263432
          Length = 2852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1850 VVELVMLL 1857





>XP_005263431
          Length = 2857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1850 VVELVMLL 1857





>XP_006714492
          Length = 2867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1850 VVELVMLL 1857





>XP_005263430
          Length = 2868

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1850 VVELVMLL 1857





>XP_005263429
          Length = 2868

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VVELLMML 9
            VVEL+M+L
Sbjct: 1850 VVELVMLL 1857





>NP_001005490
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   VVELLMML 9
           ++EL+M+L
Sbjct: 192 IIELMMLL 199





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.351    0.162    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 231,810
Number of extensions: 179
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

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