Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              18    1135
NP_061187                                                              18    1935
NP_001073953                                                           17    3301
XP_006711061                                                           17    3301
XP_006711060                                                           17    3301
XP_005244868                                                           17    3301
NP_079406                                                              17    4312
NP_001018126                                                           16    5631
NP_085146                                                              16    5631
NP_663693                                                              16    5631
NP_055616                                                              16    7355
XP_006711879                                                           16    7355
XP_005273329                                                           16    7355
NP_005742                                                              15    9605
NP_005262                                                              15    9605
NP_671714                                                              15    9605
NP_001796                                                              15    9605
NP_006633                                                              15    9605
NP_000180                                                              15    9605
NP_775102                                                              15    9605
XP_006725034                                                           15    9605
XP_006725033                                                           15    9605
XP_006725032                                                           15    9605
XP_006725031                                                           15    9605
XP_006725030                                                           15    9605
XP_006725029                                                           15    9605
XP_006725028                                                           15    9605
XP_006725027                                                           15    9605
XP_005257137                                                           15    9605
XP_005257136                                                           15    9605
XP_005257135                                                           15    9605
XP_006715890                                                           15    9605
XP_005250160                                                           15    9605
XP_005250159                                                           15    9605
XP_005264337                                                           15    9605
XP_005273079                                                           15    9605
XP_005273078                                                           15    9605
XP_005273075                                                           15    9605
XP_005273073                                                           15    9605
XP_006711792                                                           15    9605
XP_005273070                                                           15    9605
XP_006711791                                                           15    9605
XP_006711790                                                           15    9605
XP_006710853                                                           15    9605
XP_006710852                                                           15    9605
XP_006710851                                                           15    9605
XP_006710850                                                           15    9605
XP_006710849                                                           15    9605
XP_005271124                                                           15    9605
XP_006710848                                                           15    9605
XP_006710847                                                           15    9605
XP_006710846                                                           15    9605
NP_001694                                                              15    9605
>NP_115803
          Length = 1156

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IVERLRTRI 9
          IVERLR RI
Sbjct: 36 IVERLRARI 44
>NP_061187
          Length = 1133

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  IVERLRTRI 9
          +VERLR RI
Sbjct: 73 VVERLRQRI 81
>NP_001073953
          Length = 762

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           VERLR+R+
Sbjct: 492 VERLRSRV 499
>XP_006711061
          Length = 1553

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           VERLR+R+
Sbjct: 406 VERLRSRV 413
>XP_006711060
          Length = 1595

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           VERLR+R+
Sbjct: 448 VERLRSRV 455
>XP_005244868
          Length = 1639

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           VERLR+R+
Sbjct: 492 VERLRSRV 499
>NP_079406
          Length = 917

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   IVERLRTR 8
           I ERLRTR
Sbjct: 771 ISERLRTR 778

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VERLRTRI 9
           VERLRT +
Sbjct: 403 VERLRTTV 410
>NP_001018126
          Length = 364

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VERLRTRI 9
           V R+RTRI
Sbjct: 218 VNRIRTRI 225
>NP_085146
          Length = 348

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IVERLRTR 8
           +VE LRTR
Sbjct: 268 VVETLRTR 275
>NP_663693
          Length = 351

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IVERLRTR 8
           +VE LRTR
Sbjct: 271 VVETLRTR 278
>NP_055616
          Length = 2137

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ERLRTRI 9
           ERL+TR+
Sbjct: 456 ERLKTRV 462
>XP_006711879
          Length = 1364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ERLRTRI 9
           ERL+TR+
Sbjct: 456 ERLKTRV 462
>XP_005273329
          Length = 1934

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ERLRTRI 9
           ERL+TR+
Sbjct: 253 ERLKTRV 259
>NP_005742
          Length = 3907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           +ERLRT++
Sbjct: 622 LERLRTQL 629
>NP_005262
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  IVERLRTR 8
          +VE LRTR
Sbjct: 85 LVEDLRTR 92
>NP_671714
          Length = 3899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           +ERLRT++
Sbjct: 622 LERLRTQL 629
>NP_001796
          Length = 281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ERLRTRI 9
           ERLR+R+
Sbjct: 244 ERLRSRV 250
>NP_006633
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 698 VDRLRTQL 705
>NP_000180
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IVERLRTR 8
           I ERL+TR
Sbjct: 772 ISERLKTR 779
>NP_775102
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IVERLRTRI 9
           +VE+L+T+I
Sbjct: 266 LVEQLKTQI 274
>XP_006725034
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 391 VDRLRTQL 398
>XP_006725033
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 397 VDRLRTQL 404
>XP_006725032
          Length = 572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 557 VDRLRTQL 564
>XP_006725031
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 600 VDRLRTQL 607
>XP_006725030
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 645 VDRLRTQL 652
>XP_006725029
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 655 VDRLRTQL 662
>XP_006725028
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 665 VDRLRTQL 672
>XP_006725027
          Length = 723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 708 VDRLRTQL 715
>XP_005257137
          Length = 614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IVERLRTRI 9
           +VE+L+T+I
Sbjct: 266 LVEQLKTQI 274
>XP_005257136
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IVERLRTRI 9
           +VE+L+T+I
Sbjct: 268 LVEQLKTQI 276
>XP_005257135
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IVERLRTRI 9
           +VE+L+T+I
Sbjct: 268 LVEQLKTQI 276
>XP_006715890
          Length = 3860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           +ERLRT++
Sbjct: 622 LERLRTQL 629
>XP_005250160
          Length = 3939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           +ERLRT++
Sbjct: 622 LERLRTQL 629
>XP_005250159
          Length = 3952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           +ERLRT++
Sbjct: 622 LERLRTQL 629
>XP_005264337
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IVERLRTR 8
           I ERL+TR
Sbjct: 793 ISERLKTR 800
>XP_005273079
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 391 VDRLRTQL 398
>XP_005273078
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 397 VDRLRTQL 404
>XP_005273075
          Length = 572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 557 VDRLRTQL 564
>XP_005273073
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 600 VDRLRTQL 607
>XP_006711792
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 645 VDRLRTQL 652
>XP_005273070
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 655 VDRLRTQL 662
>XP_006711791
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 665 VDRLRTQL 672
>XP_006711790
          Length = 723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VERLRTRI 9
           V+RLRT++
Sbjct: 708 VDRLRTQL 715
>XP_006710853
          Length = 1478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IVERLRTRI 9
           ++ R+RTR+
Sbjct: 970 VIGRMRTRL 978
>XP_006710852
          Length = 1497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IVERLRTRI 9
           ++ R+RTR+
Sbjct: 970 VIGRMRTRL 978
>XP_006710851
          Length = 1511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IVERLRTRI 9
           ++ R+RTR+
Sbjct: 970 VIGRMRTRL 978
>XP_006710850
          Length = 1530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IVERLRTRI 9
           ++ R+RTR+
Sbjct: 970 VIGRMRTRL 978
>XP_006710849
          Length = 1530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IVERLRTRI 9
           ++ R+RTR+
Sbjct: 970 VIGRMRTRL 978
>XP_005271124
          Length = 1551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    IVERLRTRI 9
            ++ R+RTR+
Sbjct: 1025 VIGRMRTRL 1033
>XP_006710848
          Length = 1552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    IVERLRTRI 9
            ++ R+RTR+
Sbjct: 1025 VIGRMRTRL 1033
>XP_006710847
          Length = 1566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    IVERLRTRI 9
            ++ R+RTR+
Sbjct: 1025 VIGRMRTRL 1033
>XP_006710846
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    IVERLRTRI 9
            ++ R+RTR+
Sbjct: 1025 VIGRMRTRL 1033
>NP_001694
          Length = 1585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    IVERLRTRI 9
            ++ R+RTR+
Sbjct: 1025 VIGRMRTRL 1033
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.344    0.156    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 417,542
Number of extensions: 620
Number of successful extensions: 54
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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