Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1935
XP_006718908                                                           18    1935
XP_005271621                                                           18    1935
XP_006718907                                                           18    1935
XP_006718906                                                           18    1935
XP_005271619                                                           18    1935
XP_005271618                                                           18    1935
NP_001164496                                                           16    7355
NP_569075                                                              16    7355
NP_569076                                                              16    7355
NP_002830                                                              16    7355
NP_001035802                                                           16    7355
NP_569077                                                              16    7355
NP_001017361                                                           16    7355
NP_001011663                                                           16    7355
XP_005270270                                                           16    7355
XP_006716902                                                           16    7355
XP_006716901                                                           16    7355
XP_006716900                                                           16    7355
XP_006716899                                                           16    7355
XP_006716898                                                           16    7355
XP_006716897                                                           16    7355
XP_006716896                                                           16    7355
XP_006716895                                                           16    7355
XP_006716894                                                           16    7355
XP_006716893                                                           16    7355
XP_006716892                                                           16    7355
XP_006716891                                                           16    7355
XP_006716890                                                           16    7355
XP_006716889                                                           16    7355
XP_006716888                                                           16    7355
XP_006716887                                                           16    7355
XP_006716886                                                           16    7355
XP_006716885                                                           16    7355
XP_006716884                                                           16    7355
XP_006716883                                                           16    7355
XP_006716882                                                           16    7355
XP_006716881                                                           16    7355
XP_006716880                                                           16    7355
XP_006716879                                                           16    7355
XP_006716878                                                           16    7355
XP_006716877                                                           16    7355
XP_006716876                                                           16    7355
XP_006715414                                                           16    7355
NP_653258                                                              15    9605
NP_001170949                                                           15    9605
NP_001170950                                                           15    9605
NP_004787                                                              15    9605
NP_055318                                                              15    9605
XP_006724682                                                           15    9605
XP_005262138                                                           15    9605
XP_006720386                                                           15    9605
XP_006720385                                                           15    9605
XP_005268275                                                           15    9605
XP_006719406                                                           15    9605
>NP_000042
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ITVKLVVNL 9
            I VKLVVNL
Sbjct: 1643 IMVKLVVNL 1651
>XP_006718908
          Length = 1708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITVKLVVNL 9
           I VKLVVNL
Sbjct: 295 IMVKLVVNL 303
>XP_005271621
          Length = 2708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ITVKLVVNL 9
            I VKLVVNL
Sbjct: 1295 IMVKLVVNL 1303
>XP_006718907
          Length = 3050

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ITVKLVVNL 9
            I VKLVVNL
Sbjct: 1637 IMVKLVVNL 1645
>XP_006718906
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ITVKLVVNL 9
            I VKLVVNL
Sbjct: 1643 IMVKLVVNL 1651
>XP_005271619
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ITVKLVVNL 9
            I VKLVVNL
Sbjct: 1643 IMVKLVVNL 1651
>XP_005271618
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ITVKLVVNL 9
            I VKLVVNL
Sbjct: 1643 IMVKLVVNL 1651
>NP_001164496
          Length = 1505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 647 TQKLIVNL 654
>NP_569075
          Length = 1505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 657 TQKLIVNL 664
>NP_569076
          Length = 1506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 657 TQKLIVNL 664
>NP_002830
          Length = 1912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1068 TQKLIVNL 1075
>NP_001035802
          Length = 1502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 654 TQKLIVNL 661
>NP_569077
          Length = 1496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 652 TQKLIVNL 659
>NP_001017361
          Length = 217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   TVKLVVNL 9
           T+K+++NL
Sbjct: 99  TIKMIMNL 106
>NP_001011663
          Length = 350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITVKLVVNL 9
           I  KLV+NL
Sbjct: 194 IVYKLVINL 202
>XP_005270270
          Length = 278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITVKLVVNL 9
           I  KLV+NL
Sbjct: 194 IVYKLVINL 202
>XP_006716902
          Length = 1491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 644 TQKLIVNL 651
>XP_006716901
          Length = 1495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 648 TQKLIVNL 655
>XP_006716900
          Length = 1496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 652 TQKLIVNL 659
>XP_006716899
          Length = 1501

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 657 TQKLIVNL 664
>XP_006716898
          Length = 1502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 654 TQKLIVNL 661
>XP_006716897
          Length = 1505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 644 TQKLIVNL 651
>XP_006716896
          Length = 1505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 657 TQKLIVNL 664
>XP_006716895
          Length = 1505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 647 TQKLIVNL 654
>XP_006716894
          Length = 1506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 657 TQKLIVNL 664
>XP_006716893
          Length = 1520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 657 TQKLIVNL 664
>XP_006716892
          Length = 1521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TVKLVVNL 9
           T KL+VNL
Sbjct: 658 TQKLIVNL 665
>XP_006716891
          Length = 1882

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1019 TQKLIVNL 1026
>XP_006716890
          Length = 1893

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1046 TQKLIVNL 1053
>XP_006716889
          Length = 1899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1055 TQKLIVNL 1062
>XP_006716888
          Length = 1912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1069 TQKLIVNL 1076
>XP_006716887
          Length = 1912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1068 TQKLIVNL 1075
>XP_006716886
          Length = 1913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1069 TQKLIVNL 1076
>XP_006716885
          Length = 1918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1069 TQKLIVNL 1076
>XP_006716884
          Length = 1922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1059 TQKLIVNL 1066
>XP_006716883
          Length = 1923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1060 TQKLIVNL 1067
>XP_006716882
          Length = 1927

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1069 TQKLIVNL 1076
>XP_006716881
          Length = 1928

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1065 TQKLIVNL 1072
>XP_006716880
          Length = 1929

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1068 TQKLIVNL 1075
>XP_006716879
          Length = 1931

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1069 TQKLIVNL 1076
>XP_006716878
          Length = 1931

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1068 TQKLIVNL 1075
>XP_006716877
          Length = 1931

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1069 TQKLIVNL 1076
>XP_006716876
          Length = 1932

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TVKLVVNL 9
            T KL+VNL
Sbjct: 1069 TQKLIVNL 1076
>XP_006715414
          Length = 128

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   TVKLVVNL 9
           T+K+++NL
Sbjct: 99  TIKMIMNL 106
>NP_653258
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ITVKLVVNL 9
          ITV+ VVN+
Sbjct: 80 ITVRNVVNI 88
>NP_001170949
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ITVKLVVNL 9
          ITV+ VVN+
Sbjct: 22 ITVRNVVNI 30
>NP_001170950
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ITVKLVVNL 9
          ITV+ VVN+
Sbjct: 80 ITVRNVVNI 88
>NP_004787
          Length = 1061

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VKLVVNL 9
           VKL+VNL
Sbjct: 370 VKLMVNL 376
>NP_055318
          Length = 2785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ITVKLVVN 8
            ITV L+VN
Sbjct: 2007 ITVGLIVN 2014
>XP_006724682
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ITVKLVVNL 9
          ITV+ VVN+
Sbjct: 22 ITVRNVVNI 30
>XP_005262138
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ITVKLVVNL 9
          ITV+ VVN+
Sbjct: 80 ITVRNVVNI 88
>XP_006720386
          Length = 1571

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VKLVVNL 9
           VKL+VNL
Sbjct: 743 VKLMVNL 749
>XP_006720385
          Length = 1683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VKLVVNL 9
           VKL+VNL
Sbjct: 751 VKLMVNL 757
>XP_005268275
          Length = 1684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VKLVVNL 9
           VKL+VNL
Sbjct: 755 VKLMVNL 761
>XP_006719406
          Length = 2380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ITVKLVVN 8
            ITV L+VN
Sbjct: 2007 ITVGLIVN 2014
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.146    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 291,922
Number of extensions: 460
Number of successful extensions: 55
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 55
Number of HSP's successfully gapped: 55
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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