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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           18    1935
NP_001138390                                                           18    1935
NP_001138386                                                           18    1935
NP_001138387                                                           18    1935
NP_000132                                                              18    1935
NP_075259                                                              18    1935
NP_001138388                                                           18    1935
NP_001138391                                                           18    1935
NP_001138385                                                           18    1935
NP_075418                                                              18    1935
XP_006717776                                                           18    1935
XP_006717775                                                           18    1935
XP_006717774                                                           18    1935
XP_006717773                                                           18    1935
XP_006717772                                                           18    1935
XP_006717771                                                           18    1935
NP_036605                                                              16    5631
XP_006724289                                                           16    5631
XP_005261565                                                           16    5631
NP_056073                                                              16    7355
NP_078926                                                              16    7355
XP_006717082                                                           16    7355
XP_006717081                                                           16    7355
XP_006717418                                                           15    9605

>NP_001138389
          Length = 705

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 331 ITTRLSSTA 339



>NP_001138390
          Length = 704

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 330 ITTRLSSTA 338



>NP_001138386
          Length = 709

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 335 ITTRLSSTA 343



>NP_001138387
          Length = 707

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 358 ITTRLSSTA 366



>NP_000132
          Length = 821

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 447 ITTRLSSTA 455



>NP_075259
          Length = 822

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 448 ITTRLSSTA 456



>NP_001138388
          Length = 706

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 332 ITTRLSSTA 340



>NP_001138391
          Length = 680

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 359 ITTRLSSTA 367



>NP_001138385
          Length = 769

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 448 ITTRLSSTA 456



>NP_075418
          Length = 732

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 358 ITTRLSSTA 366



>XP_006717776
          Length = 806

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 466 ITTRLSSTA 474



>XP_006717775
          Length = 726

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 352 ITTRLSSTA 360



>XP_006717774
          Length = 752

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 378 ITTRLSSTA 386



>XP_006717773
          Length = 807

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 467 ITTRLSSTA 475



>XP_006717772
          Length = 838

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 464 ITTRLSSTA 472



>XP_006717771
          Length = 839

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTRLSLTA 9
           ITTRLS TA
Sbjct: 465 ITTRLSSTA 473



>NP_036605
          Length = 166

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  TTRLSLT 8
          TTR+SLT
Sbjct: 54 TTRISLT 60



>XP_006724289
          Length = 166

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  TTRLSLT 8
          TTR+SLT
Sbjct: 54 TTRISLT 60



>XP_005261565
          Length = 197

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  TTRLSLT 8
          TTR+SLT
Sbjct: 85 TTRISLT 91



>NP_056073
          Length = 1219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    TTRLSLTA 9
            +TRLSLT+
Sbjct: 1093 STRLSLTS 1100



>NP_078926
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTRLSLT 8
           +TTR SLT
Sbjct: 103 VTTRWSLT 110



>XP_006717082
          Length = 1151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    TTRLSLTA 9
            +TRLSLT+
Sbjct: 1025 STRLSLTS 1032



>XP_006717081
          Length = 1209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    TTRLSLTA 9
            +TRLSLT+
Sbjct: 1083 STRLSLTS 1090



>XP_006717418
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ITTRLSL 7
          ITTRLS+
Sbjct: 36 ITTRLSV 42




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ITTRLSL 7
          ITTRLS+
Sbjct: 43 ITTRLSV 49




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ITTRLSL 7
           ITTRLS+
Sbjct: 101 ITTRLSV 107




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ITTRLSL 7
           ITTRLS+
Sbjct: 166 ITTRLSV 172



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.124    0.290 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 235,931
Number of extensions: 260
Number of successful extensions: 27
Number of sequences better than 10000.0: 24
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)