Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

• Home Page
• Cancer-specific
• Epitope Search
• Data Retrieval
• Browse Gene
• Browse Tissue
• Sequence Similarity
• Partially Personalized
• Submit a Protein
• Vaccine Target
• Proteome Data
• NGS data
• BLAST & Predict
• Fully Personalized
• Proteins Pair
• Proteome Pair
• Advanced Tools
• Epitope Mapping
• Cross Reactivity
• Important Information
• Acknowledgement
• Algorithm
• Help
• Developers
• Contact

Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001164100                                                           16    7355
NP_060250                                                              16    7355
NP_065971                                                              16    7355
NP_079410                                                              16    7355
NP_115597                                                              16    7355
XP_006723946                                                           16    7355
XP_005260632                                                           16    7355
XP_005260631                                                           16    7355
XP_005260630                                                           16    7355
XP_005256233                                                           16    7355
XP_005256232                                                           16    7355
XP_005256231                                                           16    7355
XP_005256229                                                           16    7355
XP_005256228                                                           16    7355
XP_005256227                                                           16    7355
XP_006721346                                                           16    7355
XP_005256226                                                           16    7355
XP_006721345                                                           16    7355
XP_006721344                                                           16    7355
XP_006721343                                                           16    7355
XP_005256225                                                           16    7355
XP_006716522                                                           16    7355
XP_005251324                                                           16    7355
XP_005251323                                                           16    7355

>NP_001164100
          Length = 2581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 924 ITTFEMIL 931



>NP_060250
          Length = 2997

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ITTMELIL 8
            ITT E+IL
Sbjct: 1081 ITTFEMIL 1088



>NP_065971
          Length = 2302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 645 ITTFEMIL 652



>NP_079410
          Length = 2881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 973 ITTFEMIL 980



>NP_115597
          Length = 2715

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 574 ITTFEMIL 581



>XP_006723946
          Length = 1414

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 574 ITTFEMIL 581



>XP_005260632
          Length = 2377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 574 ITTFEMIL 581



>XP_005260631
          Length = 2667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 574 ITTFEMIL 581



>XP_005260630
          Length = 2693

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 552 ITTFEMIL 559



>XP_005256233
          Length = 2391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 466 ITTFEMIL 473



>XP_005256232
          Length = 2424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 499 ITTFEMIL 506



>XP_005256231
          Length = 2573

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 973 ITTFEMIL 980



>XP_005256229
          Length = 2881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 973 ITTFEMIL 980



>XP_005256228
          Length = 2882

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 973 ITTFEMIL 980



>XP_005256227
          Length = 2897

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 973 ITTFEMIL 980



>XP_006721346
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 973 ITTFEMIL 980



>XP_005256226
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 973 ITTFEMIL 980



>XP_006721345
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 973 ITTFEMIL 980



>XP_006721344
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 973 ITTFEMIL 980



>XP_006721343
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 973 ITTFEMIL 980



>XP_005256225
          Length = 2898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 973 ITTFEMIL 980



>XP_006716522
          Length = 2192

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITTMELIL 8
           ITT E+IL
Sbjct: 276 ITTFEMIL 283



>XP_005251324
          Length = 2996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ITTMELIL 8
            ITT E+IL
Sbjct: 1081 ITTFEMIL 1088



>XP_005251323
          Length = 2997

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ITTMELIL 8
            ITT E+IL
Sbjct: 1081 ITTFEMIL 1088



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.147    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 332,069
Number of extensions: 283
Number of successful extensions: 24
Number of sequences better than 10000.0: 24
Number of HSP's gapped: 24
Number of HSP's successfully gapped: 24
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)