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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004351                                                              18    1935
NP_002766                                                              17    4312
NP_444272                                                              17    4312
NP_443164                                                              17    4312
XP_005248097                                                           17    4312
NP_001240628                                                           16    7355
NP_001240630                                                           16    7355
NP_001006600                                                           16    7355
NP_061165                                                              16    7355
NP_001240627                                                           16    7355
NP_001240626                                                           16    7355
XP_006714723                                                           16    7355
XP_005248613                                                           16    7355
XP_005248612                                                           16    7355
XP_005248611                                                           16    7355
NP_037379                                                              15    9605
NP_659540                                                              15    9605
NP_003310                                                              15    9605
NP_597676                                                              15    9605
NP_001243779                                                           15    9605
NP_596869                                                              15    9605
NP_005062                                                              15    9605
XP_006722907                                                           15    9605
XP_006722906                                                           15    9605
XP_006722905                                                           15    9605
XP_005246888                                                           15    9605
XP_006712788                                                           15    9605
XP_006712787                                                           15    9605
XP_006712786                                                           15    9605
XP_005264323                                                           15    9605
NP_001254479                                                           15    9605
NP_597681                                                              15    9605

>NP_004351
          Length = 882

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITTLKVTAA 9
           ITTLKVT A
Sbjct: 393 ITTLKVTDA 401



>NP_002766
          Length = 480

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ITTLKVTA 8
           I TLKVTA
Sbjct: 342 INTLKVTA 349



>NP_444272
          Length = 453

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ITTLKVTA 8
           I TLKVTA
Sbjct: 319 INTLKVTA 326



>NP_443164
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ITTLKVTAA 9
          +TT+K TAA
Sbjct: 86 VTTMKPTAA 94



>XP_005248097
          Length = 357

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ITTLKVTA 8
           I TLKVTA
Sbjct: 319 INTLKVTA 326



>NP_001240628
          Length = 1419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TTLKVTAA 9
           TT+K+T+A
Sbjct: 897 TTVKITSA 904



>NP_001240630
          Length = 1367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TTLKVTAA 9
           TT+K+T+A
Sbjct: 893 TTVKITSA 900



>NP_001006600
          Length = 1302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TTLKVTAA 9
           TT+K+T+A
Sbjct: 897 TTVKITSA 904



>NP_061165
          Length = 1371

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TTLKVTAA 9
           TT+K+T+A
Sbjct: 897 TTVKITSA 904



>NP_001240627
          Length = 1346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TTLKVTAA 9
           TT+K+T+A
Sbjct: 897 TTVKITSA 904



>NP_001240626
          Length = 1412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TTLKVTAA 9
           TT+K+T+A
Sbjct: 897 TTVKITSA 904



>XP_006714723
          Length = 1246

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TTLKVTAA 9
           TT+K+T+A
Sbjct: 897 TTVKITSA 904



>XP_005248613
          Length = 1391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TTLKVTAA 9
           TT+K+T+A
Sbjct: 897 TTVKITSA 904



>XP_005248612
          Length = 1456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TTLKVTAA 9
           TT+K+T+A
Sbjct: 893 TTVKITSA 900



>XP_005248611
          Length = 1460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TTLKVTAA 9
           TT+K+T+A
Sbjct: 897 TTVKITSA 904



>NP_037379
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ITTLKVTA 8
           + T+KVTA
Sbjct: 320 VNTMKVTA 327



>NP_659540
          Length = 361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ITTLKVTA 8
           + T+KVTA
Sbjct: 255 VNTMKVTA 262



>NP_003310
          Length = 26926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2     TTLKVT 7
             TTLKVT
Sbjct: 16883 TTLKVT 16888



>NP_597676
          Length = 27051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2     TTLKVT 7
             TTLKVT
Sbjct: 17008 TTLKVT 17013



>NP_001243779
          Length = 34350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2     TTLKVT 7
             TTLKVT
Sbjct: 24307 TTLKVT 24312



>NP_596869
          Length = 33423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2     TTLKVT 7
             TTLKVT
Sbjct: 23380 TTLKVT 23385



>NP_005062
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ITTLKVTA 8
           ITT+ +TA
Sbjct: 451 ITTISITA 458



>XP_006722907
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ITTLKVTA 8
           ITT+ +TA
Sbjct: 451 ITTISITA 458



>XP_006722906
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ITTLKVTA 8
           ITT+ +TA
Sbjct: 451 ITTISITA 458



>XP_006722905
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ITTLKVTA 8
           ITT+ +TA
Sbjct: 451 ITTISITA 458



>XP_005246888
          Length = 22663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2     TTLKVT 7
             TTLKVT
Sbjct: 12620 TTLKVT 12625



>XP_006712788
          Length = 24022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2     TTLKVT 7
             TTLKVT
Sbjct: 13979 TTLKVT 13984



>XP_006712787
          Length = 33978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2     TTLKVT 7
             TTLKVT
Sbjct: 23935 TTLKVT 23940



>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2     TTLKVT 7
             TTLKVT
Sbjct: 25441 TTLKVT 25446



>XP_005264323
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ITTLKVTA 8
           + T+KVTA
Sbjct: 320 VNTMKVTA 327



>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2     TTLKVT 7
             TTLKVT
Sbjct: 25948 TTLKVT 25953



>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2     TTLKVT 7
             TTLKVT
Sbjct: 17075 TTLKVT 17080



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.118    0.273 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 225,567
Number of extensions: 221
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)