Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              18    1135
NP_444254                                                              18    1135
NP_444253                                                              18    1135
NP_444255                                                              18    1135
XP_005247551                                                           18    1135
XP_005247550                                                           18    1135
XP_006713712                                                           18    1135
XP_005247549                                                           18    1135
NP_113617                                                              17    4312
NP_001015508                                                           17    4312
NP_005413                                                              17    4312
NP_001257369                                                           17    4312
XP_006722982                                                           17    4312
XP_005260146                                                           17    4312
XP_005271710                                                           17    4312
XP_005273541                                                           17    4312
XP_005273540                                                           17    4312
NP_037489                                                              17    4312
NP_079110                                                              16    5631
NP_001243307                                                           16    5631
NP_001243308                                                           16    5631
NP_057107                                                              16    5631
XP_006724218                                                           16    5631
XP_006724217                                                           16    5631
XP_005270214                                                           16    5631
NP_689726                                                              16    5631
NP_055764                                                              16    7355
NP_690007                                                              16    7355
NP_003376                                                              16    7355
NP_003276                                                              16    7355
NP_690008                                                              16    7355
NP_071907                                                              16    7355
XP_005259213                                                           16    7355
XP_005259212                                                           16    7355
XP_005259211                                                           16    7355
XP_006723388                                                           16    7355
XP_005259210                                                           16    7355
XP_006723387                                                           16    7355
XP_005259209                                                           16    7355
NP_690009                                                              16    7355
NP_000648                                                              15    9605
NP_000624                                                              15    9605
NP_694545                                                              15    9605
NP_689916                                                              15    9605
NP_001244068                                                           15    9605
NP_000076                                                              15    9605
NP_057341                                                              15    9605
NP_001159417                                                           15    9605
NP_001269325                                                           15    9605
NP_004061                                                              15    9605
XP_006722586                                                           15    9605
XP_006715953                                                           15    9605
XP_006715952                                                           15    9605
XP_005250250                                                           15    9605
XP_006715951                                                           15    9605
XP_005250248                                                           15    9605
XP_005270849                                                           15    9605
XP_005245790                                                           15    9605
XP_006710134                                                           15    9605
XP_006710132                                                           15    9605
NP_001167579                                                           15    9605
NP_001036169                                                           15    9605
NP_002134                                                              15    9605
>NP_444256
          Length = 1794

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ITSRGRFLL 9
          ITS GRFLL
Sbjct: 73 ITSGGRFLL 81
>NP_444254
          Length = 1845

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ITSRGRFLL 9
          ITS GRFLL
Sbjct: 73 ITSGGRFLL 81
>NP_444253
          Length = 1914

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ITSRGRFLL 9
          ITS GRFLL
Sbjct: 73 ITSGGRFLL 81
>NP_444255
          Length = 1863

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ITSRGRFLL 9
          ITS GRFLL
Sbjct: 73 ITSGGRFLL 81
>XP_005247551
          Length = 1855

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ITSRGRFLL 9
          ITS GRFLL
Sbjct: 83 ITSGGRFLL 91
>XP_005247550
          Length = 1856

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ITSRGRFLL 9
          ITS GRFLL
Sbjct: 83 ITSGGRFLL 91
>XP_006713712
          Length = 1923

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ITSRGRFLL 9
          ITS GRFLL
Sbjct: 83 ITSGGRFLL 91
>XP_005247549
          Length = 1924

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ITSRGRFLL 9
          ITS GRFLL
Sbjct: 83 ITSGGRFLL 91
>NP_113617
          Length = 261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  TSRGRF 7
          TSRGRF
Sbjct: 11 TSRGRF 16
>NP_001015508
          Length = 322

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  TSRGRFL 8
          +SRGRFL
Sbjct: 79 SSRGRFL 85
>NP_005413
          Length = 2155

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TSRGRFL 8
           TSRG+FL
Sbjct: 261 TSRGQFL 267
>NP_001257369
          Length = 205

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  TSRGRF 7
          TSRGRF
Sbjct: 11 TSRGRF 16
>XP_006722982
          Length = 255

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  TSRGRF 7
          TSRGRF
Sbjct: 11 TSRGRF 16
>XP_005260146
          Length = 286

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  TSRGRF 7
          TSRGRF
Sbjct: 11 TSRGRF 16
>XP_005271710
          Length = 2150

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TSRGRFL 8
           TSRG+FL
Sbjct: 261 TSRGQFL 267
>XP_005273541
          Length = 322

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  TSRGRFL 8
          +SRGRFL
Sbjct: 79 SSRGRFL 85
>XP_005273540
          Length = 347

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  TSRGRFL 8
          +SRGRFL
Sbjct: 79 SSRGRFL 85
>NP_037489
          Length = 347

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  TSRGRFL 8
          +SRGRFL
Sbjct: 79 SSRGRFL 85
>NP_079110
          Length = 642

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ITSRGRFLL 9
           ITS GR LL
Sbjct: 507 ITSEGRSLL 515
>NP_001243307
          Length = 640

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ITSRGRFLL 9
           ITS GR LL
Sbjct: 505 ITSEGRSLL 513
>NP_001243308
          Length = 467

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ITSRGRFLL 9
           ITS GR LL
Sbjct: 332 ITSEGRSLL 340
>NP_057107
          Length = 323

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TSRGRFLL 9
          TSR RFLL
Sbjct: 14 TSRCRFLL 21
>XP_006724218
          Length = 1200

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITSRGRFLL 9
           I  RG+FLL
Sbjct: 455 ILQRGKFLL 463
>XP_006724217
          Length = 1235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITSRGRFLL 9
           I  RG+FLL
Sbjct: 455 ILQRGKFLL 463
>XP_005270214
          Length = 587

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ITSRGRFLL 9
           ITS GR LL
Sbjct: 507 ITSEGRSLL 515
>NP_689726
          Length = 1274

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITSRGRFLL 9
           I  RG+FLL
Sbjct: 494 ILQRGKFLL 502
>NP_055764
          Length = 614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ITSRGRFL 8
           +++RGRF+
Sbjct: 137 VSTRGRFM 144
>NP_690007
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITSRGRFL 8
           +TSRGR L
Sbjct: 170 LTSRGRTL 177
>NP_003376
          Length = 191

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  ITSRGRF 7
          ITSRG F
Sbjct: 91 ITSRGSF 97
>NP_003276
          Length = 1358

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ITSRGRFLL 9
            ITS+GR+ L
Sbjct: 1218 ITSQGRYEL 1226
>NP_690008
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITSRGRFL 8
           +TSRGR L
Sbjct: 172 LTSRGRTL 179
>NP_071907
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITSRGRFL 8
           +TSRGR L
Sbjct: 103 LTSRGRTL 110
>XP_005259213
          Length = 587

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITSRGRFL 8
           +TSRGR L
Sbjct: 216 LTSRGRTL 223
>XP_005259212
          Length = 587

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITSRGRFL 8
           +TSRGR L
Sbjct: 216 LTSRGRTL 223
>XP_005259211
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITSRGRFL 8
           +TSRGR L
Sbjct: 103 LTSRGRTL 110
>XP_006723388
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITSRGRFL 8
           +TSRGR L
Sbjct: 103 LTSRGRTL 110
>XP_005259210
          Length = 612

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITSRGRFL 8
           +TSRGR L
Sbjct: 121 LTSRGRTL 128
>XP_006723387
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITSRGRFL 8
           +TSRGR L
Sbjct: 170 LTSRGRTL 177
>XP_005259209
          Length = 713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITSRGRFL 8
           +TSRGR L
Sbjct: 216 LTSRGRTL 223
>NP_690009
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITSRGRFL 8
           +TSRGR L
Sbjct: 103 LTSRGRTL 110
>NP_000648
          Length = 205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TSRGRF 7
           T+RGRF
Sbjct: 125 TARGRF 130
>NP_000624
          Length = 239

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TSRGRF 7
           T+RGRF
Sbjct: 125 TARGRF 130
>NP_694545
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SRGRFLL 9
           +RGR+LL
Sbjct: 431 ARGRYLL 437
>NP_689916
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ITSRGRFLL 9
           I +RG+FL+
Sbjct: 537 IMTRGKFLV 545
>NP_001244068
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ITSRGR 6
           +TSRGR
Sbjct: 615 VTSRGR 620
>NP_000076
          Length = 687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ITSRGR 6
           +TSRGR
Sbjct: 658 VTSRGR 663
>NP_057341
          Length = 191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  ITSRGRF 7
          +TSRG F
Sbjct: 91 VTSRGSF 97
>NP_001159417
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ITSRGR 6
           +TSRGR
Sbjct: 488 VTSRGR 493
>NP_001269325
          Length = 191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  ITSRGRF 7
          +TSRG F
Sbjct: 91 VTSRGSF 97
>NP_004061
          Length = 687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ITSRGR 6
           +TSRGR
Sbjct: 658 VTSRGR 663
>XP_006722586
          Length = 224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TSRGRF 7
           T+RGRF
Sbjct: 125 TARGRF 130
>XP_006715953
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ITSRGRFLL 9
           I +RG+FL+
Sbjct: 537 IMTRGKFLV 545
>XP_006715952
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ITSRGRFLL 9
           I +RG+FL+
Sbjct: 537 IMTRGKFLV 545
>XP_005250250
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ITSRGRFLL 9
           I +RG+FL+
Sbjct: 537 IMTRGKFLV 545
>XP_006715951
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ITSRGRFLL 9
           I +RG+FL+
Sbjct: 537 IMTRGKFLV 545
>XP_005250248
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ITSRGRFLL 9
           I +RG+FL+
Sbjct: 537 IMTRGKFLV 545
>XP_005270849
          Length = 193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  ITSRGR 6
          +TSRGR
Sbjct: 91 VTSRGR 96
>XP_005245790
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ITSRGR 6
           +TSRGR
Sbjct: 657 VTSRGR 662
>XP_006710134
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ITSRGR 6
           +TSRGR
Sbjct: 305 VTSRGR 310
>XP_006710132
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ITSRGR 6
           +TSRGR
Sbjct: 489 VTSRGR 494
>NP_001167579
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RGRFLL 9
           RGRFL+
Sbjct: 244 RGRFLI 249
>NP_001036169
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ITSRGR 6
           +TSRGR
Sbjct: 657 VTSRGR 662
>NP_002134
          Length = 193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  ITSRGR 6
          +TSRGR
Sbjct: 91 VTSRGR 96
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.342    0.156    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 497,804
Number of extensions: 691
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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