Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              18    1135
NP_001075109                                                           18    1135
NP_001136245                                                           17    3301
NP_001136239                                                           17    3301
NP_001136236                                                           17    3301
NP_001136244                                                           17    3301
NP_001136238                                                           17    3301
NP_001136240                                                           17    3301
NP_001136243                                                           17    3301
NP_001136242                                                           17    3301
NP_001136235                                                           17    3301
NP_001136237                                                           17    3301
NP_001136241                                                           17    3301
NP_149045                                                              17    3301
NP_001139146                                                           17    3301
NP_001139147                                                           17    3301
XP_006718013                                                           17    3301
XP_006714450                                                           17    3301
XP_006714449                                                           17    3301
XP_006714448                                                           17    3301
XP_006714447                                                           17    3301
XP_006714446                                                           17    3301
NP_055105                                                              17    4312
XP_006717089                                                           17    4312
XP_006717088                                                           17    4312
NP_057305                                                              16    5631
XP_005268514                                                           16    5631
NP_001129115                                                           16    5631
NP_001129116                                                           16    5631
NP_000408                                                              16    7355
NP_002408                                                              16    7355
NP_001153115                                                           16    7355
NP_060819                                                              16    7355
NP_001139438                                                           16    7355
NP_037498                                                              16    7355
NP_060501                                                              16    7355
NP_001128649                                                           16    7355
NP_001128647                                                           16    7355
NP_690869                                                              16    7355
XP_005255016                                                           16    7355
XP_005255015                                                           16    7355
XP_005255014                                                           16    7355
XP_006720666                                                           16    7355
XP_006720665                                                           16    7355
XP_005255012                                                           16    7355
XP_006719300                                                           16    7355
XP_006719299                                                           16    7355
XP_005268701                                                           16    7355
XP_006717927                                                           16    7355
XP_005252503                                                           16    7355
XP_005264894                                                           16    7355
NP_001128648                                                           16    7355
NP_001129496                                                           15    9605
NP_938011                                                              15    9605
NP_001276968                                                           15    9605
NP_001276969                                                           15    9605
NP_001276994                                                           15    9605
NP_001122401                                                           15    9605
NP_002933                                                              15    9605
NP_620711                                                              15    9605
NP_006835                                                              15    9605
NP_057396                                                              15    9605
NP_006323                                                              15    9605
XP_005274596                                                           15    9605
XP_005259774                                                           15    9605
XP_005247007                                                           15    9605
NP_115991                                                              15    9605
>NP_008835
          Length = 4128

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ITPLQAVDQ 9
            ITPLQAV Q
Sbjct: 2791 ITPLQAVAQ 2799
>NP_001075109
          Length = 4097

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ITPLQAVDQ 9
            ITPLQAV Q
Sbjct: 2791 ITPLQAVAQ 2799
>NP_001136245
          Length = 1932

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           P+QA+DQ
Sbjct: 281 PIQAIDQ 287
>NP_001136239
          Length = 1915

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           P+QA+DQ
Sbjct: 266 PIQAIDQ 272
>NP_001136236
          Length = 1957

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>NP_001136244
          Length = 1677

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>NP_001136238
          Length = 1952

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>NP_001136240
          Length = 1935

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           P+QA+DQ
Sbjct: 281 PIQAIDQ 287
>NP_001136243
          Length = 1682

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           P+QA+DQ
Sbjct: 308 PIQAIDQ 314
>NP_001136242
          Length = 1539

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>NP_001136235
          Length = 1962

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           P+QA+DQ
Sbjct: 308 PIQAIDQ 314
>NP_001136237
          Length = 1886

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>NP_001136241
          Length = 1790

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           P+QA+DQ
Sbjct: 308 PIQAIDQ 314
>NP_149045
          Length = 1955

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>NP_001139146
          Length = 1004

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  TPLQAVDQ 9
          TPLQ VD+
Sbjct: 5  TPLQTVDR 12
>NP_001139147
          Length = 492

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  TPLQAVDQ 9
          TPLQ VD+
Sbjct: 5  TPLQTVDR 12
>XP_006718013
          Length = 1778

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           P+QA+DQ
Sbjct: 303 PIQAIDQ 309
>XP_006714450
          Length = 732

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  TPLQAVDQ 9
          TPLQ VD+
Sbjct: 5  TPLQTVDR 12
>XP_006714449
          Length = 747

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  TPLQAVDQ 9
          TPLQ VD+
Sbjct: 5  TPLQTVDR 12
>XP_006714448
          Length = 804

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  TPLQAVDQ 9
          TPLQ VD+
Sbjct: 5  TPLQTVDR 12
>XP_006714447
          Length = 832

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  TPLQAVDQ 9
          TPLQ VD+
Sbjct: 5  TPLQTVDR 12
>XP_006714446
          Length = 847

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  TPLQAVDQ 9
          TPLQ VD+
Sbjct: 5  TPLQTVDR 12
>NP_055105
          Length = 1098

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ITPLQAVD 8
           ITP+QAV+
Sbjct: 508 ITPVQAVN 515
>XP_006717089
          Length = 653

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  ITPLQAVD 8
          ITP+QAV+
Sbjct: 63 ITPVQAVN 70
>XP_006717088
          Length = 1024

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ITPLQAVD 8
           ITP+QAV+
Sbjct: 434 ITPVQAVN 441
>NP_057305
          Length = 460

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITPLQAVDQ 9
           I P QAVD+
Sbjct: 216 IEPAQAVDE 224
>XP_005268514
          Length = 317

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ITPLQAVDQ 9
          I P QAVD+
Sbjct: 73 IEPAQAVDE 81
>NP_001129115
          Length = 467

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITPLQAVDQ 9
           I P QAVD+
Sbjct: 223 IEPAQAVDE 231
>NP_001129116
          Length = 403

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITPLQAVDQ 9
           I P QAVD+
Sbjct: 159 IEPAQAVDE 167
>NP_000408
          Length = 272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TPLQAVDQ 9
           +P+Q VDQ
Sbjct: 111 SPMQPVDQ 118
>NP_002408
          Length = 3256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    TPLQAVDQ 9
            TP+Q +DQ
Sbjct: 1801 TPVQKLDQ 1808
>NP_001153115
          Length = 823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ITPLQAVDQ 9
           + P+Q++DQ
Sbjct: 247 VLPIQSLDQ 255
>NP_060819
          Length = 878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ITPLQAVDQ 9
           + P+Q++DQ
Sbjct: 247 VLPIQSLDQ 255
>NP_001139438
          Length = 2896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    TPLQAVDQ 9
            TP+Q +DQ
Sbjct: 1441 TPVQKLDQ 1448
>NP_037498
          Length = 822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ITPLQAV 7
           +TP+QAV
Sbjct: 659 VTPVQAV 665
>NP_060501
          Length = 1151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TPLQAVDQ 9
           TP  AVDQ
Sbjct: 454 TPTAAVDQ 461
>NP_001128649
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TPLQAVD 8
           TPL AVD
Sbjct: 160 TPLTAVD 166
>NP_001128647
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TPLQAVD 8
           TPL AVD
Sbjct: 256 TPLTAVD 262
>NP_690869
          Length = 660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TPLQAVD 8
           TPL AVD
Sbjct: 249 TPLTAVD 255
>XP_005255016
          Length = 695

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ITPLQAVDQ 9
           + P+Q++DQ
Sbjct: 247 VLPIQSLDQ 255
>XP_005255015
          Length = 823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ITPLQAVDQ 9
           + P+Q++DQ
Sbjct: 247 VLPIQSLDQ 255
>XP_005255014
          Length = 837

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ITPLQAVDQ 9
           + P+Q++DQ
Sbjct: 247 VLPIQSLDQ 255
>XP_006720666
          Length = 878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ITPLQAVDQ 9
           + P+Q++DQ
Sbjct: 247 VLPIQSLDQ 255
>XP_006720665
          Length = 878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ITPLQAVDQ 9
           + P+Q++DQ
Sbjct: 247 VLPIQSLDQ 255
>XP_005255012
          Length = 878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ITPLQAVDQ 9
           + P+Q++DQ
Sbjct: 247 VLPIQSLDQ 255
>XP_006719300
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TPLQAVD 8
           TPL AVD
Sbjct: 160 TPLTAVD 166
>XP_006719299
          Length = 660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TPLQAVD 8
           TPL AVD
Sbjct: 249 TPLTAVD 255
>XP_005268701
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TPLQAVD 8
           TPL AVD
Sbjct: 256 TPLTAVD 262
>XP_006717927
          Length = 2406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TPLQAVDQ 9
           TP+Q +DQ
Sbjct: 951 TPVQKLDQ 958
>XP_005252503
          Length = 200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TPLQAVDQ 9
           +P+Q VDQ
Sbjct: 111 SPMQPVDQ 118
>XP_005264894
          Length = 1070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TPLQAVDQ 9
           TP  AVDQ
Sbjct: 373 TPTAAVDQ 380
>NP_001128648
          Length = 660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TPLQAVD 8
           TPL AVD
Sbjct: 249 TPLTAVD 255
>NP_001129496
          Length = 1474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    TPLQAVDQ 9
            TP+QA+ +
Sbjct: 1447 TPMQAISE 1454
>NP_938011
          Length = 1630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    TPLQAVDQ 9
            TP+QA+ +
Sbjct: 1603 TPMQAISE 1610
>NP_001276968
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    PLQAVDQ 9
            PL+A+DQ
Sbjct: 1237 PLRALDQ 1243
>NP_001276969
          Length = 1443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    PLQAVDQ 9
            PL+A+DQ
Sbjct: 1237 PLRALDQ 1243
>NP_001276994
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PLQAVDQ 9
           PL+A+DQ
Sbjct: 640 PLRALDQ 646
>NP_001122401
          Length = 1394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    PLQAVDQ 9
            PL+A+DQ
Sbjct: 1249 PLRALDQ 1255
>NP_002933
          Length = 1378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    PLQAVDQ 9
            PL+A+DQ
Sbjct: 1233 PLRALDQ 1239
>NP_620711
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ITPLQA 6
           +TPLQA
Sbjct: 258 VTPLQA 263
>NP_006835
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LQAVDQ 9
           LQAVDQ
Sbjct: 160 LQAVDQ 165
>NP_057396
          Length = 641

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ITPLQAV 7
           +TPLQA+
Sbjct: 327 LTPLQAM 333
>NP_006323
          Length = 250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TPLQAVD 8
          +PLQA+D
Sbjct: 27 SPLQALD 33
>XP_005274596
          Length = 1651

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    TPLQAVDQ 9
            TP+QA+ +
Sbjct: 1624 TPMQAISE 1631
>XP_005259774
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LQAVDQ 9
           LQAVDQ
Sbjct: 160 LQAVDQ 165
>XP_005247007
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ITPLQA 6
           +TPLQA
Sbjct: 258 VTPLQA 263
>NP_115991
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ITPLQAVDQ 9
           I+PLQA +Q
Sbjct: 280 ISPLQANNQ 288
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.131    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 553,767
Number of extensions: 713
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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