Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              19     665
XP_006714104                                                           19     665
XP_005265800                                                           19     665
XP_006714103                                                           19     665
XP_006714102                                                           19     665
XP_005248910                                                           17    4312
XP_005248908                                                           17    4312
XP_006715060                                                           17    4312
XP_005248909                                                           17    4312
XP_005248907                                                           17    4312
NP_001139124                                                           17    4312
NP_001119576                                                           16    5631
NP_037409                                                              16    5631
NP_001119575                                                           16    5631
NP_001106205                                                           16    5631
NP_001159484                                                           16    5631
NP_116243                                                              16    5631
XP_005258240                                                           16    5631
XP_006722434                                                           16    5631
XP_005258114                                                           16    5631
XP_005258113                                                           16    5631
XP_005258112                                                           16    5631
XP_005258111                                                           16    5631
XP_005258108                                                           16    5631
XP_005258106                                                           16    5631
XP_005258105                                                           16    5631
XP_005258104                                                           16    5631
XP_006719423                                                           16    5631
XP_006719422                                                           16    5631
XP_005268873                                                           16    5631
XP_005268872                                                           16    5631
XP_005268870                                                           16    5631
XP_005268871                                                           16    5631
XP_005268869                                                           16    5631
XP_005268868                                                           16    5631
NP_055642                                                              16    7355
NP_775899                                                              16    7355
XP_005245703                                                           16    7355
XP_006711736                                                           16    7355
XP_005245701                                                           16    7355
XP_005245700                                                           16    7355
NP_061985                                                              15    9605
NP_689522                                                              15    9605
NP_001265202                                                           15    9605
NP_056298                                                              15    9605
NP_665699                                                              15    9605
NP_001136018                                                           15    9605
NP_001275896                                                           15    9605
NP_001275895                                                           15    9605
NP_001275894                                                           15    9605
NP_077817                                                              15    9605
NP_361013                                                              15    9605
NP_872633                                                              15    9605
NP_872634                                                              15    9605
NP_001275893                                                           15    9605
XP_006722681                                                           15    9605
XP_006722679                                                           15    9605
XP_005258294                                                           15    9605
XP_006722495                                                           15    9605
XP_005258293                                                           15    9605
XP_005269556                                                           15    9605
XP_005269555                                                           15    9605
XP_005250608                                                           15    9605
XP_006716161                                                           15    9605
XP_005250607                                                           15    9605
XP_005250606                                                           15    9605
XP_005249753                                                           15    9605
XP_005247869                                                           15    9605
XP_006713830                                                           15    9605
XP_005247867                                                           15    9605
XP_005247866                                                           15    9605
XP_005247863                                                           15    9605
XP_005247862                                                           15    9605
XP_005247861                                                           15    9605
XP_005247860                                                           15    9605
XP_005247859                                                           15    9605
>NP_006197
          Length = 1089

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ITMLEEIKL 9
           ITMLEEIK+
Sbjct: 258 ITMLEEIKV 266
>XP_006714104
          Length = 832

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ITMLEEIKL 9
           ITMLEEIK+
Sbjct: 283 ITMLEEIKV 291
>XP_005265800
          Length = 1089

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ITMLEEIKL 9
           ITMLEEIK+
Sbjct: 258 ITMLEEIKV 266
>XP_006714103
          Length = 1111

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ITMLEEIKL 9
           ITMLEEIK+
Sbjct: 280 ITMLEEIKV 288
>XP_006714102
          Length = 1114

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ITMLEEIKL 9
           ITMLEEIK+
Sbjct: 283 ITMLEEIKV 291
>XP_005248910
          Length = 244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           T LEEIKL
Sbjct: 237 TWLEEIKL 244
>XP_005248908
          Length = 244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           T LEEIKL
Sbjct: 237 TWLEEIKL 244
>XP_006715060
          Length = 244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           T LEEIKL
Sbjct: 237 TWLEEIKL 244
>XP_005248909
          Length = 244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           T LEEIKL
Sbjct: 237 TWLEEIKL 244
>XP_005248907
          Length = 244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           T LEEIKL
Sbjct: 237 TWLEEIKL 244
>NP_001139124
          Length = 244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           T LEEIKL
Sbjct: 237 TWLEEIKL 244
>NP_001119576
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TML++IK
Sbjct: 515 VTMLQDIK 522
>NP_037409
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TML++IK
Sbjct: 515 VTMLQDIK 522
>NP_001119575
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TML++IK
Sbjct: 515 VTMLQDIK 522
>NP_001106205
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TMLEE++
Sbjct: 120 VTMLEELE 127
>NP_001159484
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TMLEE++
Sbjct: 120 VTMLEELE 127
>NP_116243
          Length = 472

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           T+LEEIK
Sbjct: 438 TLLEEIK 444
>XP_005258240
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TMLEE++
Sbjct: 120 VTMLEELE 127
>XP_006722434
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TMLEE++
Sbjct: 120 VTMLEELE 127
>XP_005258114
          Length = 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           T+LEEIK
Sbjct: 203 TLLEEIK 209
>XP_005258113
          Length = 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           T+LEEIK
Sbjct: 203 TLLEEIK 209
>XP_005258112
          Length = 238

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           T+LEEIK
Sbjct: 204 TLLEEIK 210
>XP_005258111
          Length = 238

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           T+LEEIK
Sbjct: 204 TLLEEIK 210
>XP_005258108
          Length = 431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           T+LEEIK
Sbjct: 397 TLLEEIK 403
>XP_005258106
          Length = 471

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           T+LEEIK
Sbjct: 437 TLLEEIK 443
>XP_005258105
          Length = 472

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           T+LEEIK
Sbjct: 438 TLLEEIK 444
>XP_005258104
          Length = 472

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           T+LEEIK
Sbjct: 438 TLLEEIK 444
>XP_006719423
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TML++IK
Sbjct: 515 VTMLQDIK 522
>XP_006719422
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TML++IK
Sbjct: 515 VTMLQDIK 522
>XP_005268873
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TML++IK
Sbjct: 515 VTMLQDIK 522
>XP_005268872
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TML++IK
Sbjct: 515 VTMLQDIK 522
>XP_005268870
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TML++IK
Sbjct: 515 VTMLQDIK 522
>XP_005268871
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TML++IK
Sbjct: 515 VTMLQDIK 522
>XP_005268869
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TML++IK
Sbjct: 515 VTMLQDIK 522
>XP_005268868
          Length = 651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TML++IK
Sbjct: 534 VTMLQDIK 541
>NP_055642
          Length = 810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ITMLEEIKL 9
           I  LEEIKL
Sbjct: 471 IKTLEEIKL 479
>NP_775899
          Length = 4462

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TMLEEIKL 9
            T LE+IKL
Sbjct: 3019 TFLEQIKL 3026
>XP_005245703
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ITMLEEIKL 9
           I  LEEIKL
Sbjct: 135 IKTLEEIKL 143
>XP_006711736
          Length = 810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ITMLEEIKL 9
           I  LEEIKL
Sbjct: 471 IKTLEEIKL 479
>XP_005245701
          Length = 810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ITMLEEIKL 9
           I  LEEIKL
Sbjct: 471 IKTLEEIKL 479
>XP_005245700
          Length = 810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ITMLEEIKL 9
           I  LEEIKL
Sbjct: 471 IKTLEEIKL 479
>NP_061985
          Length = 2146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TMLEEIKL 9
            TMLEE+ L
Sbjct: 2091 TMLEEVFL 2098
>NP_689522
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ITMLEEIKL 9
           IT+ E++KL
Sbjct: 609 ITLQEQVKL 617
>NP_001265202
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           T L+EIKL
Sbjct: 121 TALDEIKL 128
>NP_056298
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  ITMLEEIKL 9
          +++LE++KL
Sbjct: 15 VSLLEQLKL 23
>NP_665699
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TMLE+++
Sbjct: 124 VTMLEDVE 131
>NP_001136018
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           + LEEIKL
Sbjct: 338 SQLEEIKL 345
>NP_001275896
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 294 TMLEEVE 300
>NP_001275895
          Length = 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 446 TMLEEVE 452
>NP_001275894
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 426 TMLEEVE 432
>NP_077817
          Length = 597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 446 TMLEEVE 452
>NP_361013
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           + LEEIKL
Sbjct: 338 SQLEEIKL 345
>NP_872633
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           T L+EIKL
Sbjct: 121 TALDEIKL 128
>NP_872634
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           T L+EIKL
Sbjct: 132 TALDEIKL 139
>NP_001275893
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 428 TMLEEVE 434
>XP_006722681
          Length = 1365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TMLEEIKL 9
            TMLEE+ L
Sbjct: 1310 TMLEEVFL 1317
>XP_006722679
          Length = 2128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TMLEEIKL 9
            TMLEE+ L
Sbjct: 2073 TMLEEVFL 2080
>XP_005258294
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TMLE+++
Sbjct: 124 VTMLEDVE 131
>XP_006722495
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TMLE+++
Sbjct: 124 VTMLEDVE 131
>XP_005258293
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ITMLEEIK 8
           +TMLE+++
Sbjct: 124 VTMLEDVE 131
>XP_005269556
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ITMLEEIKL 9
           IT+ E++KL
Sbjct: 431 ITLQEQVKL 439
>XP_005269555
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ITMLEEIKL 9
           IT+ E++KL
Sbjct: 431 ITLQEQVKL 439
>XP_005250608
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           T L+EIKL
Sbjct: 121 TALDEIKL 128
>XP_006716161
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           T L+EIKL
Sbjct: 121 TALDEIKL 128
>XP_005250607
          Length = 730

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           T L+EIKL
Sbjct: 132 TALDEIKL 139
>XP_005250606
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TMLEEIKL 9
           T L+EIKL
Sbjct: 169 TALDEIKL 176
>XP_005249753
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  ITMLEEIKL 9
          +++LE++KL
Sbjct: 15 VSLLEQLKL 23
>XP_005247869
          Length = 373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 187 TMLEEVE 193
>XP_006713830
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 270 TMLEEVE 276
>XP_005247867
          Length = 480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 294 TMLEEVE 300
>XP_005247866
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 446 TMLEEVE 452
>XP_005247863
          Length = 597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 446 TMLEEVE 452
>XP_005247862
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 446 TMLEEVE 452
>XP_005247861
          Length = 612

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 426 TMLEEVE 432
>XP_005247860
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 446 TMLEEVE 452
>XP_005247859
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TMLEEIK 8
           TMLEE++
Sbjct: 446 TMLEEVE 452
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.142    0.330 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 521,857
Number of extensions: 871
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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