Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002430                                                              18    1935
NP_066973                                                              17    2528
NP_001171545                                                           17    2528
XP_005268816                                                           17    2528
XP_005268815                                                           17    2528
XP_005268814                                                           17    2528
XP_005268813                                                           17    2528
XP_005268812                                                           17    2528
XP_005268811                                                           17    2528
NP_004930                                                              17    4312
NP_000334                                                              17    4312
NP_001243243                                                           17    4312
NP_001073892                                                           17    4312
NP_001001991                                                           16    5631
NP_001269605                                                           16    5631
NP_056245                                                              16    5631
NP_001269604                                                           16    5631
NP_003032                                                              16    5631
NP_859070                                                              16    5631
NP_061722                                                              16    5631
NP_115649                                                              16    5631
NP_001231664                                                           16    5631
XP_006721136                                                           16    5631
XP_006721135                                                           16    5631
XP_005272295                                                           16    5631
XP_005245884                                                           16    5631
XP_005245882                                                           16    5631
XP_006710614                                                           16    5631
XP_005245881                                                           16    5631
XP_005245880                                                           16    5631
XP_006710613                                                           16    5631
XP_005245879                                                           16    5631
NP_114089                                                              16    5631
NP_075573                                                              16    7355
NP_075571                                                              16    7355
NP_001269201                                                           15    9605
NP_004665                                                              15    9605
NP_001248761                                                           15    9605
NP_001098684                                                           15    9605
NP_001075224                                                           15    9605
NP_001265844                                                           15    9605
NP_000492                                                              15    9605
NP_001265842                                                           15    9605
NP_001265846                                                           15    9605
NP_001265843                                                           15    9605
NP_001265868                                                           15    9605
NP_079095                                                              15    9605
NP_001275584                                                           15    9605
NP_001275583                                                           15    9605
NP_001122103                                                           15    9605
XP_005257745                                                           15    9605
XP_006722156                                                           15    9605
XP_006722155                                                           15    9605
XP_006722154                                                           15    9605
XP_006716476                                                           15    9605
XP_006715941                                                           15    9605
XP_006715939                                                           15    9605
XP_006715937                                                           15    9605
XP_005250245                                                           15    9605
XP_005250244                                                           15    9605
XP_005264617                                                           15    9605
NP_001136155                                                           15    9605
>NP_002430
          Length = 1137

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ITGGIAARS 9
            IT GIAARS
Sbjct: 1059 ITRGIAARS 1067
>NP_066973
          Length = 1076

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  GGIAARS 9
          GGIAARS
Sbjct: 86 GGIAARS 92
>NP_001171545
          Length = 1061

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  GGIAARS 9
          GGIAARS
Sbjct: 86 GGIAARS 92
>XP_005268816
          Length = 1062

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  GGIAARS 9
          GGIAARS
Sbjct: 87 GGIAARS 93
>XP_005268815
          Length = 1077

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  GGIAARS 9
          GGIAARS
Sbjct: 87 GGIAARS 93
>XP_005268814
          Length = 1102

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  GGIAARS 9
          GGIAARS
Sbjct: 60 GGIAARS 66
>XP_005268813
          Length = 1114

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  GGIAARS 9
          GGIAARS
Sbjct: 87 GGIAARS 93
>XP_005268812
          Length = 1128

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  GGIAARS 9
          GGIAARS
Sbjct: 87 GGIAARS 93
>XP_005268811
          Length = 1129

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  GGIAARS 9
          GGIAARS
Sbjct: 87 GGIAARS 93
>NP_004930
          Length = 740

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITGGIAAR 8
           I GG+AAR
Sbjct: 323 IIGGVAAR 330
>NP_000334
          Length = 664

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ITGGIAA 7
           ITGG+AA
Sbjct: 193 ITGGLAA 199
>NP_001243243
          Length = 537

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ITGGIAA 7
          ITGG+AA
Sbjct: 66 ITGGLAA 72
>NP_001073892
          Length = 1140

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GGIAARS 9
           GG+AARS
Sbjct: 178 GGLAARS 184
>NP_001001991
          Length = 720

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TGGIAARS 9
           TGGIAA S
Sbjct: 665 TGGIAAVS 672
>NP_001269605
          Length = 609

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TGGIAARS 9
           TGGIAA S
Sbjct: 554 TGGIAAVS 561
>NP_056245
          Length = 737

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TGGIAARS 9
           TGGIAA S
Sbjct: 682 TGGIAAVS 689
>NP_001269604
          Length = 680

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TGGIAARS 9
           TGGIAA S
Sbjct: 625 TGGIAAVS 632
>NP_003032
          Length = 672

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ITGGIAA 7
           +TGG+AA
Sbjct: 190 VTGGLAA 196
>NP_859070
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ITGGIAA 7
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>NP_061722
          Length = 1007

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITGGIAARS 9
           + GGI ARS
Sbjct: 230 VDGGIPARS 238
>NP_115649
          Length = 195

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ITGGIAAR 8
           + GG+AAR
Sbjct: 125 VNGGLAAR 132
>NP_001231664
          Length = 125

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  ITGGIAAR 8
          + GG+AAR
Sbjct: 55 VNGGLAAR 62
>XP_006721136
          Length = 425

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ITGGIAA 7
           +TGG+AA
Sbjct: 178 VTGGLAA 184
>XP_006721135
          Length = 698

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ITGGIAA 7
           +TGG+AA
Sbjct: 190 VTGGLAA 196
>XP_005272295
          Length = 961

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TGGIAARS 9
           TGG +ARS
Sbjct: 120 TGGASARS 127
>XP_005245884
          Length = 594

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ITGGIAA 7
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>XP_005245882
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ITGGIAA 7
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>XP_006710614
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ITGGIAA 7
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>XP_005245881
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ITGGIAA 7
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>XP_005245880
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ITGGIAA 7
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>XP_006710613
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ITGGIAA 7
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>XP_005245879
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ITGGIAA 7
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>NP_114089
          Length = 884

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITGGIAARS 9
           + GGI ARS
Sbjct: 230 VDGGIPARS 238
>NP_075573
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ITGGIAAR 8
           +TGG+A R
Sbjct: 177 LTGGLAER 184
>NP_075571
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ITGGIAAR 8
           +TGG+A R
Sbjct: 177 LTGGLAER 184
>NP_001269201
          Length = 489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITGGIAARS 9
           + GGIAA S
Sbjct: 144 LNGGIAAGS 152
>NP_004665
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITGGIAARS 9
           + GGIAA S
Sbjct: 283 LNGGIAAGS 291
>NP_001248761
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITGGIAARS 9
           + GGIAA S
Sbjct: 189 LNGGIAAGS 197
>NP_001098684
          Length = 534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITGGIAARS 9
           + GGIAA S
Sbjct: 189 LNGGIAAGS 197
>NP_001075224
          Length = 705

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GGIAAR 8
           GG+AAR
Sbjct: 676 GGVAAR 681
>NP_001265844
          Length = 730

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GGIAAR 8
           GG+AAR
Sbjct: 701 GGVAAR 706
>NP_000492
          Length = 724

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GGIAAR 8
           GG+AAR
Sbjct: 695 GGVAAR 700
>NP_001265842
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GGIAAR 8
           GG+AAR
Sbjct: 614 GGVAAR 619
>NP_001265846
          Length = 714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GGIAAR 8
           GG+AAR
Sbjct: 685 GGVAAR 690
>NP_001265843
          Length = 700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GGIAAR 8
           GG+AAR
Sbjct: 671 GGVAAR 676
>NP_001265868
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GGIAAR 8
           GG+AAR
Sbjct: 757 GGVAAR 762
>NP_079095
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ITGGIAA 7
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>NP_001275584
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ITGGIAA 7
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>NP_001275583
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ITGGIAA 7
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>NP_001122103
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ITGGIAA 7
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>XP_005257745
          Length = 132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ITGGIAA 7
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>XP_006722156
          Length = 132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ITGGIAA 7
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>XP_006722155
          Length = 132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ITGGIAA 7
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>XP_006722154
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ITGGIAA 7
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>XP_006716476
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ITGGIAARS 9
           + GGIAA S
Sbjct: 283 LNGGIAAGS 291
>XP_006715941
          Length = 556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GGIAAR 8
           GG+AAR
Sbjct: 527 GGVAAR 532
>XP_006715939
          Length = 687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GGIAAR 8
           GG+AAR
Sbjct: 658 GGVAAR 663
>XP_006715937
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GGIAAR 8
           GG+AAR
Sbjct: 677 GGVAAR 682
>XP_005250245
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GGIAAR 8
           GG+AAR
Sbjct: 681 GGVAAR 686
>XP_005250244
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GGIAAR 8
           GG+AAR
Sbjct: 683 GGVAAR 688
>XP_005264617
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  TGGIAARS 9
          TGG AAR+
Sbjct: 30 TGGPAARA 37
>NP_001136155
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  TGGIAARS 9
          TGG AAR+
Sbjct: 30 TGGPAARA 37
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.133    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 488,230
Number of extensions: 436
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package