Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_689966                                                              17    2528
XP_005249005                                                           17    2528
XP_005249004                                                           17    2528
XP_005249003                                                           17    2528
XP_005249000                                                           17    2528
NP_872393                                                              17    4312
XP_006712515                                                           17    4312
XP_006712514                                                           17    4312
XP_006712513                                                           17    4312
XP_006712512                                                           17    4312
XP_006712511                                                           17    4312
XP_006712510                                                           17    4312
XP_006712509                                                           17    4312
XP_005246533                                                           17    4312
XP_006712508                                                           17    4312
NP_115893                                                              17    4312
NP_001037853                                                           16    5631
NP_001037852                                                           16    5631
NP_077317                                                              16    5631
NP_001166245                                                           16    5631
XP_005276647                                                           16    5631
XP_005276648                                                           16    5631
XP_006726767                                                           16    5631
XP_006723108                                                           16    5631
XP_005258618                                                           16    5631
NP_997208                                                              16    5631
NP_055918                                                              16    7355
NP_055455                                                              16    7355
NP_068770                                                              16    7355
NP_714544                                                              16    7355
XP_006724219                                                           16    7355
XP_006724218                                                           16    7355
XP_006724217                                                           16    7355
XP_006723946                                                           16    7355
XP_006722785                                                           16    7355
XP_006720470                                                           16    7355
XP_006716795                                                           16    7355
XP_005247035                                                           16    7355
XP_006712939                                                           16    7355
XP_006712938                                                           16    7355
XP_006712937                                                           16    7355
XP_006712936                                                           16    7355
XP_005247034                                                           16    7355
XP_006710049                                                           16    7355
XP_005276017                                                           16    7355
NP_689726                                                              16    7355
NP_001265852                                                           15    9605
NP_001265853                                                           15    9605
NP_001092315                                                           15    9605
NP_001191150                                                           15    9605
NP_055051                                                              15    9605
NP_005910                                                              15    9605
NP_055653                                                              15    9605
NP_055429                                                              15    9605
NP_597999                                                              15    9605
NP_057450                                                              15    9605
NP_005294                                                              15    9605
XP_005261932                                                           15    9605
XP_005273371                                                           15    9605
XP_005273370                                                           15    9605
>NP_689966
          Length = 993

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ISSFLRP 7
           +SSFLRP
Sbjct: 985 VSSFLRP 991
>XP_005249005
          Length = 531

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ISSFLRP 7
           +SSFLRP
Sbjct: 523 VSSFLRP 529
>XP_005249004
          Length = 955

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ISSFLRP 7
           +SSFLRP
Sbjct: 947 VSSFLRP 953
>XP_005249003
          Length = 987

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ISSFLRP 7
           +SSFLRP
Sbjct: 979 VSSFLRP 985
>XP_005249000
          Length = 1009

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ISSFLRP 7
            +SSFLRP
Sbjct: 1001 VSSFLRP 1007
>NP_872393
          Length = 3234

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SSFLRPSL 9
          S+FLRP L
Sbjct: 31 SAFLRPKL 38
>XP_006712515
          Length = 3232

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SSFLRPSL 9
          S+FLRP L
Sbjct: 31 SAFLRPKL 38
>XP_006712514
          Length = 2496

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SSFLRPSL 9
          S+FLRP L
Sbjct: 31 SAFLRPKL 38
>XP_006712513
          Length = 3220

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SSFLRPSL 9
          S+FLRP L
Sbjct: 31 SAFLRPKL 38
>XP_006712512
          Length = 3237

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SSFLRPSL 9
          S+FLRP L
Sbjct: 31 SAFLRPKL 38
>XP_006712511
          Length = 3256

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SSFLRPSL 9
          S+FLRP L
Sbjct: 31 SAFLRPKL 38
>XP_006712510
          Length = 3305

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SSFLRPSL 9
          S+FLRP L
Sbjct: 31 SAFLRPKL 38
>XP_006712509
          Length = 3319

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SSFLRPSL 9
          S+FLRP L
Sbjct: 31 SAFLRPKL 38
>XP_005246533
          Length = 3323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SSFLRPSL 9
          S+FLRP L
Sbjct: 31 SAFLRPKL 38
>XP_006712508
          Length = 3324

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SSFLRPSL 9
          S+FLRP L
Sbjct: 31 SAFLRPKL 38
>NP_115893
          Length = 3258

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SSFLRPSL 9
          S+FLRP L
Sbjct: 31 SAFLRPKL 38
>NP_001037853
          Length = 423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSFLRPSL 9
           SS+LRP L
Sbjct: 241 SSYLRPHL 248
>NP_001037852
          Length = 430

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSFLRPSL 9
           SS+LRP L
Sbjct: 248 SSYLRPHL 255
>NP_077317
          Length = 430

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSFLRPSL 9
           SS+LRP L
Sbjct: 248 SSYLRPHL 255
>NP_001166245
          Length = 716

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           I+ FLRP+L
Sbjct: 227 ITYFLRPNL 235
>XP_005276647
          Length = 596

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           +SS+LRP +
Sbjct: 119 VSSWLRPGI 127

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           +SS+LRP +
Sbjct: 252 VSSWLRPGI 260

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           +SS+LRP +
Sbjct: 404 VSSWLRPGI 412
>XP_005276648
          Length = 596

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           +SS+LRP +
Sbjct: 119 VSSWLRPGI 127

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           +SS+LRP +
Sbjct: 252 VSSWLRPGI 260

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           +SS+LRP +
Sbjct: 404 VSSWLRPGI 412
>XP_006726767
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           +SS+LRP +
Sbjct: 119 VSSWLRPGI 127

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           +SS+LRP +
Sbjct: 252 VSSWLRPGI 260

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           +SS+LRP +
Sbjct: 404 VSSWLRPGI 412
>XP_006723108
          Length = 520

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ISSFLRPSL 9
          I+ FLRP+L
Sbjct: 31 ITYFLRPNL 39
>XP_005258618
          Length = 682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           I+ FLRP+L
Sbjct: 227 ITYFLRPNL 235
>NP_997208
          Length = 716

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           I+ FLRP+L
Sbjct: 227 ITYFLRPNL 235
>NP_055918
          Length = 1925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ISSFLRPS 8
           +S+FL PS
Sbjct: 280 VSAFLHPS 287
>NP_055455
          Length = 1199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SSFLRPS 8
           SSFL PS
Sbjct: 361 SSFLNPS 367
>NP_068770
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSFLRPSL 9
           SSF +PSL
Sbjct: 211 SSFYQPSL 218
>NP_714544
          Length = 1775

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ISSFLRPS 8
            +SSFLR S
Sbjct: 1572 VSSFLRQS 1579
>XP_006724219
          Length = 1157

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SSFLRPSL 9
            +SFLRP +
Sbjct: 1048 NSFLRPEI 1055
>XP_006724218
          Length = 1200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SSFLRPSL 9
            +SFLRP +
Sbjct: 1091 NSFLRPEI 1098
>XP_006724217
          Length = 1235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SSFLRPSL 9
            +SFLRP +
Sbjct: 1126 NSFLRPEI 1133
>XP_006723946
          Length = 1414

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ISSFLRP 7
            ++SFLRP
Sbjct: 1386 LASFLRP 1392
>XP_006722785
          Length = 363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ISSFLRPSL 9
          + SFL PSL
Sbjct: 2  LDSFLLPSL 10
>XP_006720470
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ISSFLRPS 8
           +SSFLR S
Sbjct: 814 VSSFLRQS 821
>XP_006716795
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SSFLRPSL 9
           SSF +PSL
Sbjct: 211 SSFYQPSL 218
>XP_005247035
          Length = 971

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SSFLRPS 8
           SSFL PS
Sbjct: 361 SSFLNPS 367
>XP_006712939
          Length = 972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SSFLRPS 8
           SSFL PS
Sbjct: 361 SSFLNPS 367
>XP_006712938
          Length = 1138

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SSFLRPS 8
           SSFL PS
Sbjct: 361 SSFLNPS 367
>XP_006712937
          Length = 1199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SSFLRPS 8
           SSFL PS
Sbjct: 361 SSFLNPS 367
>XP_006712936
          Length = 1199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SSFLRPS 8
           SSFL PS
Sbjct: 361 SSFLNPS 367
>XP_005247034
          Length = 1199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SSFLRPS 8
           SSFL PS
Sbjct: 361 SSFLNPS 367
>XP_006710049
          Length = 293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ISSFLRPS 8
          +SSFLR S
Sbjct: 90 VSSFLRQS 97
>XP_005276017
          Length = 610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ISSFLRP 7
           ++SFLRP
Sbjct: 571 LASFLRP 577
>NP_689726
          Length = 1274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SSFLRPSL 9
            +SFLRP +
Sbjct: 1165 NSFLRPEI 1172
>NP_001265852
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           +SSF+ P+L
Sbjct: 113 VSSFVDPAL 121
>NP_001265853
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           +SSF+ P+L
Sbjct: 151 VSSFVDPAL 159
>NP_001092315
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           +SSF+ P+L
Sbjct: 170 VSSFVDPAL 178
>NP_001191150
          Length = 172

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ISSFLRP 7
           I SFLRP
Sbjct: 145 ILSFLRP 151
>NP_055051
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           ++ F+RPSL
Sbjct: 486 LNIFVRPSL 494
>NP_005910
          Length = 365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SSFLRPS 8
           ++FLRPS
Sbjct: 294 ATFLRPS 300
>NP_055653
          Length = 1171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ISSFLRPSL 9
           +SSF  PSL
Sbjct: 179 VSSFPSPSL 187
>NP_055429
          Length = 1843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ISSFLRPSL 9
           + SFL+P L
Sbjct: 784 LDSFLQPEL 792
>NP_597999
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SFLRPSL 9
           SFLRP++
Sbjct: 135 SFLRPTV 141
>NP_057450
          Length = 220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  FLRPSL 9
          FLRPS+
Sbjct: 61 FLRPSI 66
>NP_005294
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           ++SFL P+L
Sbjct: 245 VASFLYPNL 253
>XP_005261932
          Length = 1171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ISSFLRPSL 9
           +SSF  PSL
Sbjct: 179 VSSFPSPSL 187
>XP_005273371
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           ++ F+RPSL
Sbjct: 425 LNIFVRPSL 433
>XP_005273370
          Length = 679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISSFLRPSL 9
           ++ F+RPSL
Sbjct: 485 LNIFVRPSL 493
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.140    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 698,675
Number of extensions: 1892
Number of successful extensions: 66
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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