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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     869
NP_009297                                                              19     869
NP_001239264                                                           17    4312
NP_116255                                                              17    4312
XP_005254784                                                           17    4312
XP_005254783                                                           17    4312
NP_689594                                                              16    5631
NP_001186074                                                           16    5631
NP_001186072                                                           16    5631
NP_001073278                                                           16    5631
XP_006712319                                                           16    5631
NP_001186073                                                           16    5631
NP_001122302                                                           16    7355
NP_001122303                                                           16    7355
NP_001158302                                                           16    7355
NP_001122301                                                           16    7355
NP_001729                                                              16    7355
NP_055054                                                              16    7355
NP_076985                                                              15    9605

>NP_005148
          Length = 1130

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ISRSSEQMA 9
            ISR+SEQMA
Sbjct: 1043 ISRNSEQMA 1051



>NP_009297
          Length = 1149

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ISRSSEQMA 9
            ISR+SEQMA
Sbjct: 1062 ISRNSEQMA 1070



>NP_001239264
          Length = 1302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    ISRSSEQM 8
            ISRS EQM
Sbjct: 1091 ISRSREQM 1098



>NP_116255
          Length = 1302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    ISRSSEQM 8
            ISRS EQM
Sbjct: 1091 ISRSREQM 1098



>XP_005254784
          Length = 1303

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    ISRSSEQM 8
            ISRS EQM
Sbjct: 1091 ISRSREQM 1098



>XP_005254783
          Length = 1303

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    ISRSSEQM 8
            ISRS EQM
Sbjct: 1091 ISRSREQM 1098



>NP_689594
          Length = 3549

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SRSSEQMA 9
           SRSS++MA
Sbjct: 297 SRSSQEMA 304



>NP_001186074
          Length = 716

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  SRSSEQMA 9
          SRSS++MA
Sbjct: 75 SRSSQEMA 82



>NP_001186072
          Length = 971

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SRSSEQMA 9
           SRSS++MA
Sbjct: 330 SRSSQEMA 337



>NP_001073278
          Length = 938

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SRSSEQMA 9
           SRSS++MA
Sbjct: 297 SRSSQEMA 304



>XP_006712319
          Length = 3308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  SRSSEQMA 9
          SRSS++MA
Sbjct: 56 SRSSQEMA 63



>NP_001186073
          Length = 3327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  SRSSEQMA 9
          SRSS++MA
Sbjct: 75 SRSSQEMA 82



>NP_001122302
          Length = 261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ISRSSEQMA 9
           IS SSEQ+A
Sbjct: 217 ISVSSEQLA 225



>NP_001122303
          Length = 261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ISRSSEQMA 9
           IS SSEQ+A
Sbjct: 217 ISVSSEQLA 225



>NP_001158302
          Length = 261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ISRSSEQMA 9
           IS SSEQ+A
Sbjct: 217 ISVSSEQLA 225



>NP_001122301
          Length = 261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ISRSSEQMA 9
           IS SSEQ+A
Sbjct: 217 ISVSSEQLA 225



>NP_001729
          Length = 261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ISRSSEQMA 9
           IS SSEQ+A
Sbjct: 217 ISVSSEQLA 225



>NP_055054
          Length = 351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  RSSEQMA 9
          RSSE+MA
Sbjct: 29 RSSEEMA 35



>NP_076985
          Length = 1104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ISRSSEQ 7
           ISRSSE+
Sbjct: 201 ISRSSEE 207



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.102    0.214 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 286,956
Number of extensions: 284
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)