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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              18    1482
NP_653080                                                              18    1482
XP_005267292                                                           18    1482
XP_005267291                                                           18    1482
XP_005267290                                                           18    1482
NP_060542                                                              16    5631
NP_001269845                                                           16    7355
NP_001077395                                                           16    7355
NP_079356                                                              16    7355
NP_002378                                                              16    7355
NP_001078846                                                           16    7355
NP_001269848                                                           16    7355
NP_001073863                                                           16    7355
XP_005274361                                                           16    7355
XP_005251250                                                           16    7355
XP_005251248                                                           16    7355
XP_006716506                                                           16    7355
XP_005251246                                                           16    7355
XP_005272048                                                           16    7355
XP_006714680                                                           16    7355
NP_001139019                                                           15    9605
NP_116294                                                              15    9605
NP_958357                                                              15    9605
NP_003426                                                              15    9605
XP_005271318                                                           15    9605
XP_005271317                                                           15    9605
XP_005271314                                                           15    9605

>NP_005091
          Length = 1782

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ISKDRSEAS 9
            ISKD SEAS
Sbjct: 1630 ISKDMSEAS 1638



>NP_653080
          Length = 1684

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ISKDRSEAS 9
            ISKD SEAS
Sbjct: 1532 ISKDMSEAS 1540



>XP_005267292
          Length = 1677

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ISKDRSEAS 9
            ISKD SEAS
Sbjct: 1525 ISKDMSEAS 1533



>XP_005267291
          Length = 1684

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ISKDRSEAS 9
            ISKD SEAS
Sbjct: 1532 ISKDMSEAS 1540



>XP_005267290
          Length = 1782

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ISKDRSEAS 9
            ISKD SEAS
Sbjct: 1630 ISKDMSEAS 1638



>NP_060542
          Length = 2144

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ISKDRSEA 8
            ISK+R+EA
Sbjct: 2011 ISKERAEA 2018



>NP_001269845
          Length = 845

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ISKDRSEAS 9
          I  DR+EAS
Sbjct: 60 IDSDRAEAS 68



>NP_001077395
          Length = 308

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  ISKDRSE 7
          ISKDR E
Sbjct: 15 ISKDRKE 21



>NP_079356
          Length = 308

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  ISKDRSE 7
          ISKDR E
Sbjct: 15 ISKDRKE 21



>NP_002378
          Length = 829

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ISKDRSEAS 9
           +SK RSE+S
Sbjct: 332 LSKTRSESS 340



>NP_001078846
          Length = 1019

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ISKDRSEAS 9
           +SK RSE+S
Sbjct: 522 LSKTRSESS 530



>NP_001269848
          Length = 876

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ISKDRSEAS 9
          I  DR+EAS
Sbjct: 70 IDSDRAEAS 78



>NP_001073863
          Length = 915

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ISKDRSEAS 9
           I  DR+EAS
Sbjct: 130 IDSDRAEAS 138



>XP_005274361
          Length = 218

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  ISKDRSE 7
          ISKDR E
Sbjct: 15 ISKDRKE 21



>XP_005251250
          Length = 815

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ISKDRSEAS 9
           I  DR+EAS
Sbjct: 130 IDSDRAEAS 138



>XP_005251248
          Length = 848

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ISKDRSEAS 9
           I  DR+EAS
Sbjct: 130 IDSDRAEAS 138



>XP_006716506
          Length = 855

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ISKDRSEAS 9
          I  DR+EAS
Sbjct: 70 IDSDRAEAS 78



>XP_005251246
          Length = 883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ISKDRSEAS 9
           I  DR+EAS
Sbjct: 130 IDSDRAEAS 138



>XP_005272048
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ISKDRSEAS 9
           +SK RSE+S
Sbjct: 332 LSKTRSESS 340



>XP_006714680
          Length = 1002

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ISKDRSEAS 9
           +SK RSE+S
Sbjct: 483 LSKTRSESS 491



>NP_001139019
          Length = 401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KDRSEAS 9
           KDR EAS
Sbjct: 139 KDRHEAS 145



>NP_116294
          Length = 401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KDRSEAS 9
           KDR EAS
Sbjct: 139 KDRHEAS 145



>NP_958357
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ISKDRSE 7
          +SKD+SE
Sbjct: 78 LSKDKSE 84



>NP_003426
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ISKDRSEAS 9
           + +D+SEAS
Sbjct: 106 LRRDKSEAS 114



>XP_005271318
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ISKDRSE 7
          +SKD+SE
Sbjct: 78 LSKDKSE 84



>XP_005271317
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ISKDRSE 7
          +SKD+SE
Sbjct: 78 LSKDKSE 84



>XP_005271314
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ISKDRSE 7
          +SKD+SE
Sbjct: 78 LSKDKSE 84



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.288    0.104    0.229 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 451,598
Number of extensions: 579
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)