Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

• Home Page
• Cancer-specific
• Epitope Search
• Data Retrieval
• Browse Gene
• Browse Tissue
• Sequence Similarity
• Partially Personalized
• Submit a Protein
• Vaccine Target
• Proteome Data
• NGS data
• BLAST & Predict
• Fully Personalized
• Proteins Pair
• Proteome Pair
• Advanced Tools
• Epitope Mapping
• Cross Reactivity
• Important Information
• Acknowledgement
• Algorithm
• Help
• Developers
• Contact

Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001234926                                                           17    4312
NP_002947                                                              17    4312
NP_937883                                                              17    4312
XP_006719618                                                           17    4312
XP_006719617                                                           17    4312
XP_006719616                                                           17    4312
XP_006719615                                                           17    4312
XP_006719614                                                           17    4312
XP_005253652                                                           17    4312
XP_005253651                                                           17    4312
XP_005253650                                                           17    4312
NP_000411                                                              15    9605
XP_005277045                                                           15    9605
XP_005250050                                                           15    9605

>NP_001234926
          Length = 1438

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    SISLTSAL 9
            SIS+TSAL
Sbjct: 1234 SISITSAL 1241



>NP_002947
          Length = 1427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    SISLTSAL 9
            SIS+TSAL
Sbjct: 1223 SISITSAL 1230



>NP_937883
          Length = 1392

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    SISLTSAL 9
            SIS+TSAL
Sbjct: 1188 SISITSAL 1195



>XP_006719618
          Length = 1394

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    SISLTSAL 9
            SIS+TSAL
Sbjct: 1188 SISITSAL 1195



>XP_006719617
          Length = 1401

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    SISLTSAL 9
            SIS+TSAL
Sbjct: 1195 SISITSAL 1202



>XP_006719616
          Length = 1405

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    SISLTSAL 9
            SIS+TSAL
Sbjct: 1199 SISITSAL 1206



>XP_006719615
          Length = 1429

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    SISLTSAL 9
            SIS+TSAL
Sbjct: 1223 SISITSAL 1230



>XP_006719614
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    SISLTSAL 9
            SIS+TSAL
Sbjct: 1234 SISITSAL 1241



>XP_005253652
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    SISLTSAL 9
            SIS+TSAL
Sbjct: 1234 SISITSAL 1241



>XP_005253651
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    SISLTSAL 9
            SIS+TSAL
Sbjct: 1234 SISITSAL 1241



>XP_005253650
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    SISLTSAL 9
            SIS+TSAL
Sbjct: 1234 SISITSAL 1241



>NP_000411
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ISISLTSAL 9
           +SIS+TS L
Sbjct: 274 LSISITSRL 282



>XP_005277045
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ISISLTSAL 9
           +SIS+TS L
Sbjct: 286 LSISITSRL 294



>XP_005250050
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ISISLTSAL 9
           +SIS+TS L
Sbjct: 286 LSISITSRL 294



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.122    0.258 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 207,873
Number of extensions: 151
Number of successful extensions: 14
Number of sequences better than 10000.0: 14
Number of HSP's gapped: 14
Number of HSP's successfully gapped: 14
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)