Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_056285                                                              17    2528
XP_005264310                                                           17    2528
XP_005264309                                                           17    2528
XP_005264308                                                           17    2528
XP_006712048                                                           17    2528
NP_444256                                                              17    3301
NP_444254                                                              17    3301
NP_444253                                                              17    3301
NP_444255                                                              17    3301
XP_005247551                                                           17    3301
XP_005247550                                                           17    3301
XP_006713712                                                           17    3301
XP_005247549                                                           17    3301
NP_001243398                                                           17    4312
NP_036462                                                              17    4312
NP_001243397                                                           17    4312
NP_001138550                                                           17    4312
NP_003408                                                              17    4312
NP_001018857                                                           17    4312
XP_005259487                                                           17    4312
XP_006723570                                                           17    4312
XP_005269721                                                           17    4312
NP_057409                                                              16    5631
NP_598009                                                              16    5631
NP_001265663                                                           16    5631
NP_057408                                                              16    5631
NP_001092882                                                           16    5631
NP_006757                                                              16    5631
NP_001092883                                                           16    5631
XP_005273706                                                           16    5631
NP_115285                                                              16    7355
NP_001005851                                                           15    9605
NP_001035939                                                           15    9605
NP_775929                                                              15    9605
NP_001123504                                                           15    9605
NP_001123503                                                           15    9605
NP_997278                                                              15    9605
NP_689690                                                              15    9605
XP_005258975                                                           15    9605
XP_005258974                                                           15    9605
XP_005258973                                                           15    9605
XP_005258972                                                           15    9605
XP_005258971                                                           15    9605
XP_006723136                                                           15    9605
XP_005258650                                                           15    9605
XP_005258649                                                           15    9605
XP_005258652                                                           15    9605
XP_005258648                                                           15    9605
XP_006723135                                                           15    9605
XP_005258647                                                           15    9605
XP_005258610                                                           15    9605
XP_005260009                                                           15    9605
XP_005260008                                                           15    9605
XP_006722842                                                           15    9605
XP_005260007                                                           15    9605
XP_005260004                                                           15    9605
XP_005260002                                                           15    9605
XP_006722841                                                           15    9605
XP_005260001                                                           15    9605
XP_005259999                                                           15    9605
XP_005259998                                                           15    9605
XP_006722840                                                           15    9605
XP_006722839                                                           15    9605
XP_006722838                                                           15    9605
XP_006722837                                                           15    9605
XP_005259954                                                           15    9605
XP_006715149                                                           15    9605
XP_005249139                                                           15    9605
XP_005265147                                                           15    9605
XP_006713180                                                           15    9605
NP_060126                                                              15    9605
NP_001070249                                                           15    9605
NP_940937                                                              15    9605
>NP_056285
          Length = 653

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IRSSSLTQS 9
           +R SSLTQS
Sbjct: 240 LRKSSLTQS 248
>XP_005264310
          Length = 531

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IRSSSLTQS 9
           +R SSLTQS
Sbjct: 240 LRKSSLTQS 248
>XP_005264309
          Length = 1324

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IRSSSLTQS 9
           +R SSLTQS
Sbjct: 240 LRKSSLTQS 248
>XP_005264308
          Length = 1218

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IRSSSLTQS 9
           +R SSLTQS
Sbjct: 240 LRKSSLTQS 248
>XP_006712048
          Length = 1249

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IRSSSLTQS 9
           +R SSLTQS
Sbjct: 240 LRKSSLTQS 248
>NP_444256
          Length = 1794

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IRSSSLTQS 9
            IRSSSLT S
Sbjct: 1274 IRSSSLTLS 1282
>NP_444254
          Length = 1845

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IRSSSLTQS 9
            IRSSSLT S
Sbjct: 1274 IRSSSLTLS 1282
>NP_444253
          Length = 1914

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IRSSSLTQS 9
            IRSSSLT S
Sbjct: 1343 IRSSSLTLS 1351
>NP_444255
          Length = 1863

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IRSSSLTQS 9
            IRSSSLT S
Sbjct: 1343 IRSSSLTLS 1351
>XP_005247551
          Length = 1855

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IRSSSLTQS 9
            IRSSSLT S
Sbjct: 1284 IRSSSLTLS 1292
>XP_005247550
          Length = 1856

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IRSSSLTQS 9
            IRSSSLT S
Sbjct: 1353 IRSSSLTLS 1361
>XP_006713712
          Length = 1923

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IRSSSLTQS 9
            IRSSSLT S
Sbjct: 1353 IRSSSLTLS 1361
>XP_005247549
          Length = 1924

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IRSSSLTQS 9
            IRSSSLT S
Sbjct: 1353 IRSSSLTLS 1361
>NP_001243398
          Length = 1781

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IRSSSLTQS 9
            + SSSLTQS
Sbjct: 1417 LTSSSLTQS 1425
>NP_036462
          Length = 2073

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IRSSSLTQS 9
            + SSSLTQS
Sbjct: 1709 LTSSSLTQS 1717
>NP_001243397
          Length = 1890

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IRSSSLTQS 9
            + SSSLTQS
Sbjct: 1526 LTSSSLTQS 1534
>NP_001138550
          Length = 494

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSSSLTQ
Sbjct: 417 RSSSLTQ 423
>NP_003408
          Length = 627

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSSSLTQ
Sbjct: 550 RSSSLTQ 556
>NP_001018857
          Length = 627

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSSSLTQ
Sbjct: 550 RSSSLTQ 556
>XP_005259487
          Length = 628

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSSSLTQ
Sbjct: 551 RSSSLTQ 557
>XP_006723570
          Length = 627

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSSSLTQ
Sbjct: 550 RSSSLTQ 556
>XP_005269721
          Length = 2073

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IRSSSLTQS 9
            + SSSLTQS
Sbjct: 1709 LTSSSLTQS 1717
>NP_057409
          Length = 621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IRSSSLTQ 8
           ++SSSLTQ
Sbjct: 513 VQSSSLTQ 520
>NP_598009
          Length = 653

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IRSSSLTQ 8
           ++SSSLTQ
Sbjct: 545 VQSSSLTQ 552
>NP_001265663
          Length = 611

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IRSSSLTQ 8
           ++SSSLTQ
Sbjct: 503 VQSSSLTQ 510
>NP_057408
          Length = 548

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IRSSSLTQ 8
           ++SSSLTQ
Sbjct: 440 VQSSSLTQ 447
>NP_001092882
          Length = 2004

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    SSSLTQS 9
            SSSLTQS
Sbjct: 1595 SSSLTQS 1601
>NP_006757
          Length = 2004

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    SSSLTQS 9
            SSSLTQS
Sbjct: 1595 SSSLTQS 1601
>NP_001092883
          Length = 2004

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    SSSLTQS 9
            SSSLTQS
Sbjct: 1595 SSSLTQS 1601
>XP_005273706
          Length = 1997

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    SSSLTQS 9
            SSSLTQS
Sbjct: 1588 SSSLTQS 1594
>NP_115285
          Length = 282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RSSSLTQS 9
           RSSS+T+S
Sbjct: 245 RSSSMTRS 252
>NP_001005851
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 260 RSSNLTQ 266
>NP_001035939
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IRSSSLTQ 8
           IRSS LT+
Sbjct: 457 IRSSQLTE 464
>NP_775929
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 173 RSSNLTQ 179
>NP_001123504
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 383 RSSTLTQ 389
>NP_001123503
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 383 RSSTLTQ 389
>NP_997278
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 436 RSSNLTQ 442
>NP_689690
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IRSSSLTQ 8
           IRSS LT+
Sbjct: 457 IRSSQLTE 464
>XP_005258975
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 436 RSSNLTQ 442
>XP_005258974
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 436 RSSNLTQ 442
>XP_005258973
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 436 RSSNLTQ 442
>XP_005258972
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 436 RSSNLTQ 442
>XP_005258971
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 436 RSSNLTQ 442
>XP_006723136
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 260 RSSNLTQ 266
>XP_005258650
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 260 RSSNLTQ 266
>XP_005258649
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 261 RSSNLTQ 267
>XP_005258652
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 261 RSSNLTQ 267
>XP_005258648
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 261 RSSNLTQ 267
>XP_006723135
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 261 RSSNLTQ 267
>XP_005258647
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 261 RSSNLTQ 267
>XP_005258610
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IRSSSLTQ 8
           IRSS LT+
Sbjct: 457 IRSSQLTE 464
>XP_005260009
          Length = 283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 240 RSSTLTQ 246
>XP_005260008
          Length = 310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 267 RSSTLTQ 273
>XP_006722842
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 268 RSSTLTQ 274
>XP_005260007
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 268 RSSTLTQ 274
>XP_005260004
          Length = 357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 314 RSSTLTQ 320
>XP_005260002
          Length = 357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 314 RSSTLTQ 320
>XP_006722841
          Length = 361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 318 RSSTLTQ 324
>XP_005260001
          Length = 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 346 RSSTLTQ 352
>XP_005259999
          Length = 425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 382 RSSTLTQ 388
>XP_005259998
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 383 RSSTLTQ 389
>XP_006722840
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 387 RSSTLTQ 393
>XP_006722839
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 388 RSSTLTQ 394
>XP_006722838
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 395 RSSTLTQ 401
>XP_006722837
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 396 RSSTLTQ 402
>XP_005259954
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSSSLT+
Sbjct: 486 RSSSLTE 492
>XP_006715149
          Length = 358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSSSLT+
Sbjct: 288 RSSSLTE 294
>XP_005249139
          Length = 358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSSSLT+
Sbjct: 288 RSSSLTE 294
>XP_005265147
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 173 RSSNLTQ 179
>XP_006713180
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 173 RSSNLTQ 179
>NP_060126
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSS+LTQ
Sbjct: 311 RSSTLTQ 317
>NP_001070249
          Length = 358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSSSLT+
Sbjct: 288 RSSSLTE 294
>NP_940937
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RSSSLTQ 8
           RSSSLT+
Sbjct: 486 RSSSLTE 492
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.102    0.213 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 294,869
Number of extensions: 544
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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