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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004110                                                              20     390
NP_001005211                                                           18    1935
NP_001001923                                                           18    1935
NP_653271                                                              17    3301
NP_001269353                                                           17    3301
NP_001242940                                                           17    4312
NP_005791                                                              17    4312
NP_060821                                                              17    4312
NP_001242939                                                           17    4312
NP_056538                                                              17    4312
NP_001242938                                                           17    4312
NP_001242937                                                           17    4312
NP_001242936                                                           17    4312
XP_005266271                                                           17    4312
XP_006719814                                                           17    4312
XP_005266270                                                           17    4312
XP_005269081                                                           17    4312
XP_005250453                                                           17    4312
XP_005248810                                                           17    4312
XP_006715597                                                           17    4312
XP_005248809                                                           17    4312
NP_001695                                                              17    4312
NP_001017975                                                           16    5631
XP_006710458                                                           16    5631
NP_055524                                                              16    7355
NP_064583                                                              16    7355
XP_005257584                                                           16    7355
NP_005735                                                              16    7355
NP_036218                                                              15    9605
NP_940948                                                              15    9605
NP_001004719                                                           15    9605
NP_055426                                                              15    9605
NP_699197                                                              15    9605
XP_006715467                                                           15    9605
XP_005247022                                                           15    9605

>NP_004110
          Length = 993

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   IRNTLLYT 8
           IRNTLLYT
Sbjct: 160 IRNTLLYT 167



>NP_001005211
          Length = 314

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   IRNTLLYT 8
           IRN LLYT
Sbjct: 126 IRNPLLYT 133



>NP_001001923
          Length = 320

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   IRNTLLYT 8
           IRN LLYT
Sbjct: 130 IRNPLLYT 137



>NP_653271
          Length = 1454

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    IRNTLLYTF 9
            I+NT  YTF
Sbjct: 1409 IKNTQTYTF 1417



>NP_001269353
          Length = 963

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IRNTLLYTF 9
           I+NT  YTF
Sbjct: 918 IKNTQTYTF 926



>NP_001242940
          Length = 682

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRNTLLYT 8
           +RNT+ YT
Sbjct: 567 VRNTVTYT 574



>NP_005791
          Length = 1092

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   NTLLYT 8
           NTLLYT
Sbjct: 277 NTLLYT 282



>NP_060821
          Length = 1430

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRNTLLYTF 9
            I+N +LYT+
Sbjct: 1357 IKNKVLYTY 1365



>NP_001242939
          Length = 682

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRNTLLYT 8
           +RNT+ YT
Sbjct: 567 VRNTVTYT 574



>NP_056538
          Length = 782

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRNTLLYT 8
           +RNT+ YT
Sbjct: 667 VRNTVTYT 674



>NP_001242938
          Length = 720

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRNTLLYT 8
           +RNT+ YT
Sbjct: 605 VRNTVTYT 612



>NP_001242937
          Length = 782

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRNTLLYT 8
           +RNT+ YT
Sbjct: 667 VRNTVTYT 674



>NP_001242936
          Length = 782

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRNTLLYT 8
           +RNT+ YT
Sbjct: 667 VRNTVTYT 674



>XP_005266271
          Length = 911

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   NTLLYT 8
           NTLLYT
Sbjct: 96  NTLLYT 101



>XP_006719814
          Length = 1086

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   NTLLYT 8
           NTLLYT
Sbjct: 271 NTLLYT 276



>XP_005266270
          Length = 1092

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   NTLLYT 8
           NTLLYT
Sbjct: 277 NTLLYT 282



>XP_005269081
          Length = 1389

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRNTLLYTF 9
            I+N +LYT+
Sbjct: 1357 IKNKVLYTY 1365



>XP_005250453
          Length = 720

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRNTLLYT 8
           +RNT+ YT
Sbjct: 605 VRNTVTYT 612



>XP_005248810
          Length = 1078

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  IRNTLLYTF 9
          +RN L+Y F
Sbjct: 4  VRNLLIYIF 12



>XP_006715597
          Length = 1489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  IRNTLLYTF 9
          +RN L+Y F
Sbjct: 4  VRNLLIYIF 12



>XP_005248809
          Length = 1522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  IRNTLLYTF 9
          +RN L+Y F
Sbjct: 4  VRNLLIYIF 12



>NP_001695
          Length = 1522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  IRNTLLYTF 9
          +RN L+Y F
Sbjct: 4  VRNLLIYIF 12



>NP_001017975
          Length = 1435

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IRNTLLY 7
           IR+TLLY
Sbjct: 719 IRSTLLY 725



>XP_006710458
          Length = 846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IRNTLLY 7
           IR+TLLY
Sbjct: 130 IRSTLLY 136



>NP_055524
          Length = 3546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    NTLLYTF 9
            NT+ YTF
Sbjct: 2087 NTMRYTF 2093



>NP_064583
          Length = 483

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RNTLLYTF 9
           + TLL+TF
Sbjct: 356 KRTLLFTF 363



>XP_005257584
          Length = 483

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RNTLLYTF 9
           + TLL+TF
Sbjct: 356 KRTLLFTF 363



>NP_005735
          Length = 557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RNTLLYTF 9
           R TL+YT+
Sbjct: 469 RATLMYTY 476



>NP_036218
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TLLYTF 9
           TLLYT+
Sbjct: 878 TLLYTY 883



>NP_940948
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  RNTLLYT 8
          RNT +YT
Sbjct: 4  RNTQMYT 10



>NP_001004719
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   IRNTLLYT 8
           +RN ++YT
Sbjct: 283 LRNPIIYT 290



>NP_055426
          Length = 5596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NTLLYTF 9
           NTLL+ F
Sbjct: 812 NTLLFAF 818



>NP_699197
          Length = 3571

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RNTLLYT 8
            RNT+ YT
Sbjct: 1982 RNTVTYT 1988



>XP_006715467
          Length = 5550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NTLLYTF 9
           NTLL+ F
Sbjct: 812 NTLLFAF 818



>XP_005247022
          Length = 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TLLYTF 9
           TLLYT+
Sbjct: 486 TLLYTY 491



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.151    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 419,686
Number of extensions: 630
Number of successful extensions: 35
Number of sequences better than 10000.0: 35
Number of HSP's gapped: 35
Number of HSP's successfully gapped: 35
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)