Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001165349                                                           17    2528
NP_001165350                                                           17    2528
NP_005360                                                              17    2528
NP_001165347                                                           17    2528
XP_006724820                                                           17    2528
XP_005262471                                                           17    2528
XP_005262470                                                           17    2528
NP_001165348                                                           17    2528
NP_001093325                                                           17    2528
NP_001159827                                                           16    5631
NP_000102                                                              16    5631
XP_006715936                                                           16    5631
NP_065805                                                              16    7355
NP_055871                                                              16    7355
XP_005247728                                                           16    7355
XP_006713777                                                           16    7355
NP_036222                                                              15    9605
NP_001009571                                                           15    9605
NP_060424                                                              15    9605
NP_001161412                                                           15    9605
NP_055454                                                              15    9605
XP_005250765                                                           15    9605
XP_005250764                                                           15    9605
XP_005250763                                                           15    9605
XP_005250762                                                           15    9605
XP_005250761                                                           15    9605
XP_005250760                                                           15    9605
XP_005250759                                                           15    9605
XP_005250758                                                           15    9605
XP_005250757                                                           15    9605
XP_005250756                                                           15    9605
XP_005250755                                                           15    9605
XP_005250754                                                           15    9605
XP_005250753                                                           15    9605
XP_005250752                                                           15    9605
XP_005249641                                                           15    9605
XP_006710603                                                           15    9605
XP_006710602                                                           15    9605
XP_006710601                                                           15    9605
XP_006710600                                                           15    9605
XP_005270757                                                           15    9605
XP_006710599                                                           15    9605
XP_006710598                                                           15    9605
XP_006710597                                                           15    9605
XP_006710596                                                           15    9605
XP_006710595                                                           15    9605
XP_006710594                                                           15    9605
XP_006710593                                                           15    9605
XP_006710592                                                           15    9605
XP_006710591                                                           15    9605
XP_006710590                                                           15    9605
XP_006710589                                                           15    9605
XP_006710588                                                           15    9605
XP_006710587                                                           15    9605
XP_006710586                                                           15    9605
XP_006710585                                                           15    9605
XP_005270755                                                           15    9605
XP_006710584                                                           15    9605
XP_005270754                                                           15    9605
XP_005270753                                                           15    9605
XP_006710583                                                           15    9605
XP_005270752                                                           15    9605
XP_006710582                                                           15    9605
XP_005270751                                                           15    9605
NP_066939                                                              15    9605
>NP_001165349
          Length = 860

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RLRLDLYL 9
           RLRLD YL
Sbjct: 621 RLRLDSYL 628
>NP_001165350
          Length = 941

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RLRLDLYL 9
           RLRLD YL
Sbjct: 637 RLRLDSYL 644
>NP_005360
          Length = 925

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RLRLDLYL 9
           RLRLD YL
Sbjct: 621 RLRLDSYL 628
>NP_001165347
          Length = 1001

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RLRLDLYL 9
           RLRLD YL
Sbjct: 697 RLRLDSYL 704
>XP_006724820
          Length = 902

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RLRLDLYL 9
           RLRLD YL
Sbjct: 598 RLRLDSYL 605
>XP_005262471
          Length = 1005

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RLRLDLYL 9
           RLRLD YL
Sbjct: 766 RLRLDSYL 773
>XP_005262470
          Length = 1044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RLRLDLYL 9
           RLRLD YL
Sbjct: 740 RLRLDSYL 747
>NP_001165348
          Length = 821

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RLRLDLYL 9
           RLRLD YL
Sbjct: 582 RLRLDSYL 589
>NP_001093325
          Length = 985

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RLRLDLYL 9
           RLRLD YL
Sbjct: 681 RLRLDSYL 688
>NP_001159827
          Length = 308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  RLRLDLY 8
          RLRLD Y
Sbjct: 7  RLRLDTY 13
>NP_000102
          Length = 764

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   IRLRLDLYL 9
           IR+++D+Y+
Sbjct: 675 IRIKVDVYI 683
>XP_006715936
          Length = 764

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   IRLRLDLYL 9
           IR+++D+Y+
Sbjct: 675 IRIKVDVYI 683
>NP_065805
          Length = 1444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RLRLDLYL 9
           +LR DLY+
Sbjct: 812 KLRTDLYI 819
>NP_055871
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   RLRLDLY 8
           RLRLD Y
Sbjct: 111 RLRLDKY 117
>XP_005247728
          Length = 1413

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RLRLDLYL 9
           +LR DLY+
Sbjct: 781 KLRTDLYI 788
>XP_006713777
          Length = 1424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RLRLDLYL 9
           +LR DLY+
Sbjct: 792 KLRTDLYI 799
>NP_036222
          Length = 5430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1056 IRLRLEEY 1063
>NP_001009571
          Length = 1255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>NP_060424
          Length = 1296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>NP_001161412
          Length = 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>NP_055454
          Length = 1564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    RLDLYL 9
            R+DLYL
Sbjct: 1296 RIDLYL 1301
>XP_005250765
          Length = 1250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005250764
          Length = 1258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005250763
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005250762
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005250761
          Length = 1265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005250760
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005250759
          Length = 1293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005250758
          Length = 1298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005250757
          Length = 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005250756
          Length = 1301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005250755
          Length = 1303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005250754
          Length = 1305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005250753
          Length = 1305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005250752
          Length = 1308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RLRLDLYL 9
          R+RL LY+
Sbjct: 82 RIRLQLYV 89
>XP_005249641
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IRLRLD 6
           IRLRLD
Sbjct: 807 IRLRLD 812
>XP_006710603
          Length = 5324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1056 IRLRLEEY 1063
>XP_006710602
          Length = 7391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1056 IRLRLEEY 1063
>XP_006710601
          Length = 4720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_006710600
          Length = 5384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1056 IRLRLEEY 1063
>XP_005270757
          Length = 5460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_006710599
          Length = 5656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_006710598
          Length = 7553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1046 IRLRLEEY 1053
>XP_006710597
          Length = 7451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1056 IRLRLEEY 1063
>XP_006710596
          Length = 7512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1005 IRLRLEEY 1012
>XP_006710595
          Length = 7526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1019 IRLRLEEY 1026
>XP_006710594
          Length = 7528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1021 IRLRLEEY 1028
>XP_006710593
          Length = 7539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1032 IRLRLEEY 1039
>XP_006710592
          Length = 7544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1037 IRLRLEEY 1044
>XP_006710591
          Length = 7558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1051 IRLRLEEY 1058
>XP_006710590
          Length = 7563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1056 IRLRLEEY 1063
>XP_006710589
          Length = 7595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1088 IRLRLEEY 1095
>XP_006710588
          Length = 7614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_006710587
          Length = 7645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_006710586
          Length = 7645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_006710585
          Length = 7657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_005270755
          Length = 7663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_006710584
          Length = 7686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_005270754
          Length = 7694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_005270753
          Length = 7700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_006710583
          Length = 7702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_005270752
          Length = 7717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_006710582
          Length = 7720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>XP_005270751
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRLRLDLY 8
            IRLRL+ Y
Sbjct: 1216 IRLRLEEY 1223
>NP_066939
          Length = 1119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IRLRLD 6
           IRLRLD
Sbjct: 807 IRLRLD 812
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.349    0.172    0.483 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 471,331
Number of extensions: 646
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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