Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002430                                                              19     665
NP_004450                                                              17    4312
NP_872579                                                              17    4312
XP_005257219                                                           17    4312
XP_005257218                                                           17    4312
XP_005257217                                                           17    4312
XP_005257216                                                           17    4312
XP_005257215                                                           17    4312
XP_005257214                                                           17    4312
XP_005257213                                                           17    4312
XP_005257212                                                           17    4312
XP_006721834                                                           17    4312
XP_005257211                                                           17    4312
XP_005257210                                                           17    4312
XP_005257209                                                           17    4312
XP_005257208                                                           17    4312
XP_006721833                                                           17    4312
XP_005257207                                                           17    4312
NP_079415                                                              16    5631
NP_001258395                                                           16    5631
NP_001124319                                                           16    5631
NP_004199                                                              16    5631
NP_665811                                                              16    5631
NP_001269779                                                           16    5631
NP_065196                                                              16    5631
NP_001116436                                                           16    5631
NP_001271209                                                           16    5631
NP_001271210                                                           16    5631
XP_005267899                                                           16    5631
XP_006720257                                                           16    5631
XP_005264505                                                           16    5631
XP_005264504                                                           16    5631
XP_005264503                                                           16    5631
XP_005264502                                                           16    5631
XP_005264501                                                           16    5631
XP_005264499                                                           16    5631
NP_115646                                                              16    7355
XP_006711023                                                           16    7355
NP_004743                                                              15    9605
NP_055325                                                              15    9605
NP_149015                                                              15    9605
NP_008949                                                              15    9605
NP_060009                                                              15    9605
NP_001244237                                                           15    9605
XP_006721125                                                           15    9605
XP_006717006                                                           15    9605
XP_006717005                                                           15    9605
XP_006717004                                                           15    9605
XP_006717003                                                           15    9605
XP_005251736                                                           15    9605
XP_006715989                                                           15    9605
>NP_002430
          Length = 1137

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IRDVKSLTV 9
            IRDVKSLT+
Sbjct: 998  IRDVKSLTL 1006
>NP_004450
          Length = 2903

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1577 DIKSLTV 1583
>NP_872579
          Length = 2920

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1451 DIKSLTV 1457
>XP_005257219
          Length = 2038

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1577 DIKSLTV 1583
>XP_005257218
          Length = 2957

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1577 DIKSLTV 1583
>XP_005257217
          Length = 2961

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1577 DIKSLTV 1583
>XP_005257216
          Length = 3015

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1577 DIKSLTV 1583
>XP_005257215
          Length = 3032

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1451 DIKSLTV 1457
>XP_005257214
          Length = 3094

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1513 DIKSLTV 1519
>XP_005257213
          Length = 3095

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1514 DIKSLTV 1520
>XP_005257212
          Length = 3095

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1514 DIKSLTV 1520
>XP_006721834
          Length = 3100

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1577 DIKSLTV 1583
>XP_005257211
          Length = 3100

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1577 DIKSLTV 1583
>XP_005257210
          Length = 3104

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1577 DIKSLTV 1583
>XP_005257209
          Length = 3148

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1577 DIKSLTV 1583
>XP_005257208
          Length = 3157

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1576 DIKSLTV 1582
>XP_006721833
          Length = 3158

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1577 DIKSLTV 1583
>XP_005257207
          Length = 3158

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    DVKSLTV 9
            D+KSLTV
Sbjct: 1577 DIKSLTV 1583
>NP_079415
          Length = 665

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  RDVKSLTV 9
          RD KSLT+
Sbjct: 51 RDSKSLTI 58
>NP_001258395
          Length = 818

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  RDVKSLTV 9
          RD KSLT+
Sbjct: 51 RDSKSLTI 58
>NP_001124319
          Length = 324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RDVKSLTV 9
           R+VKS+T+
Sbjct: 298 REVKSITI 305
>NP_004199
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RDVKSLTV 9
           R+VKS+T+
Sbjct: 298 REVKSITI 305
>NP_665811
          Length = 609

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RDVKSLTV 9
           R+VKS+T+
Sbjct: 294 REVKSITI 301
>NP_001269779
          Length = 817

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRDVKSLT 8
           + D+KSLT
Sbjct: 613 VEDIKSLT 620
>NP_065196
          Length = 764

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRDVKSLT 8
           + D+KSLT
Sbjct: 560 VEDIKSLT 567
>NP_001116436
          Length = 849

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRDVKSLT 8
           + D+KSLT
Sbjct: 645 VEDIKSLT 652
>NP_001271209
          Length = 820

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRDVKSLT 8
           + D+KSLT
Sbjct: 597 VEDIKSLT 604
>NP_001271210
          Length = 594

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRDVKSLT 8
           + D+KSLT
Sbjct: 371 VEDIKSLT 378
>XP_005267899
          Length = 833

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRDVKSLT 8
           + D+KSLT
Sbjct: 610 VEDIKSLT 617
>XP_006720257
          Length = 833

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRDVKSLT 8
           + D+KSLT
Sbjct: 610 VEDIKSLT 617
>XP_005264505
          Length = 544

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRDVKSLT 8
           + D+KSLT
Sbjct: 340 VEDIKSLT 347
>XP_005264504
          Length = 641

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRDVKSLT 8
           + D+KSLT
Sbjct: 437 VEDIKSLT 444
>XP_005264503
          Length = 757

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRDVKSLT 8
           + D+KSLT
Sbjct: 560 VEDIKSLT 567
>XP_005264502
          Length = 789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRDVKSLT 8
           + D+KSLT
Sbjct: 592 VEDIKSLT 599
>XP_005264501
          Length = 796

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRDVKSLT 8
           + D+KSLT
Sbjct: 592 VEDIKSLT 599
>XP_005264499
          Length = 842

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IRDVKSLT 8
           + D+KSLT
Sbjct: 645 VEDIKSLT 652
>NP_115646
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IRDVKSLTV 9
           +RD+KSL +
Sbjct: 538 LRDLKSLKI 546
>XP_006711023
          Length = 808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IRDVKSLTV 9
           +RD+KSL +
Sbjct: 543 LRDLKSLKI 551
>NP_004743
          Length = 506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IRDVKSLT 8
           +R+VKSL+
Sbjct: 405 VREVKSLS 412
>NP_055325
          Length = 4935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRDVKSLT 8
            I+D KSLT
Sbjct: 1030 IKDSKSLT 1037
>NP_149015
          Length = 5142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRDVKSLT 8
            I+D KSLT
Sbjct: 1030 IKDSKSLT 1037
>NP_008949
          Length = 2325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    IRDVKSL 7
            IR+VKSL
Sbjct: 1642 IREVKSL 1648
>NP_060009
          Length = 4116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    IRDVKSLTV 9
            I D+K LTV
Sbjct: 2379 ITDLKQLTV 2387
>NP_001244237
          Length = 190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  DVKSLT 8
          DVKSLT
Sbjct: 19 DVKSLT 24
>XP_006721125
          Length = 4070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    IRDVKSLTV 9
            I D+K LTV
Sbjct: 2333 ITDLKQLTV 2341
>XP_006717006
          Length = 1760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    IRDVKSL 7
            IR+VKSL
Sbjct: 1062 IREVKSL 1068
>XP_006717005
          Length = 1788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    IRDVKSL 7
            IR+VKSL
Sbjct: 1090 IREVKSL 1096
>XP_006717004
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    IRDVKSL 7
            IR+VKSL
Sbjct: 1642 IREVKSL 1648
>XP_006717003
          Length = 2278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    IRDVKSL 7
            IR+VKSL
Sbjct: 1642 IREVKSL 1648
>XP_005251736
          Length = 2325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    IRDVKSL 7
            IR+VKSL
Sbjct: 1642 IREVKSL 1648
>XP_006715989
          Length = 5148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IRDVKSLT 8
            I+D KSLT
Sbjct: 1030 IKDSKSLT 1037
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.137    0.334 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 351,978
Number of extensions: 338
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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