Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1482
XP_006716142                                                           18    1482
XP_005250088                                                           18    1482
XP_006716141                                                           18    1482
XP_005250085                                                           18    1482
XP_006716140                                                           18    1482
XP_005250084                                                           18    1482
XP_005250083                                                           18    1482
XP_005250082                                                           18    1482
NP_056261                                                              18    1935
XP_006711822                                                           18    1935
XP_006711821                                                           18    1935
NP_065883                                                              17    4312
NP_060718                                                              17    4312
XP_005245423                                                           17    4312
XP_005245425                                                           17    4312
NP_001034484                                                           16    5631
NP_001271254                                                           16    5631
NP_001181                                                              16    5631
NP_001158245                                                           16    5631
NP_078836                                                              16    5631
XP_005269208                                                           16    5631
XP_005269207                                                           16    5631
XP_005251556                                                           16    5631
XP_006716862                                                           16    5631
XP_006716861                                                           16    5631
XP_006716860                                                           16    5631
XP_006716859                                                           16    5631
XP_006716858                                                           16    5631
NP_775960                                                              16    7355
XP_005251991                                                           16    7355
NP_001243643                                                           15    9605
NP_002151                                                              15    9605
NP_001164434                                                           15    9605
NP_570123                                                              15    9605
NP_991402                                                              15    9605
XP_006717164                                                           15    9605
XP_005252030                                                           15    9605
XP_006717163                                                           15    9605
XP_006717162                                                           15    9605
XP_006717161                                                           15    9605
XP_006717160                                                           15    9605
XP_005252029                                                           15    9605
XP_006717159                                                           15    9605
XP_006714594                                                           15    9605
>NP_733751
          Length = 4911

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IRAVVLPGV 9
           I AVVLPGV
Sbjct: 916 IGAVVLPGV 924
>XP_006716142
          Length = 4927

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IRAVVLPGV 9
           I AVVLPGV
Sbjct: 917 IGAVVLPGV 925
>XP_005250088
          Length = 4928

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IRAVVLPGV 9
           I AVVLPGV
Sbjct: 917 IGAVVLPGV 925
>XP_006716141
          Length = 4959

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IRAVVLPGV 9
           I AVVLPGV
Sbjct: 917 IGAVVLPGV 925
>XP_005250085
          Length = 4979

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IRAVVLPGV 9
           I AVVLPGV
Sbjct: 917 IGAVVLPGV 925
>XP_006716140
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IRAVVLPGV 9
           I AVVLPGV
Sbjct: 917 IGAVVLPGV 925
>XP_005250084
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IRAVVLPGV 9
           I AVVLPGV
Sbjct: 917 IGAVVLPGV 925
>XP_005250083
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IRAVVLPGV 9
           I AVVLPGV
Sbjct: 916 IGAVVLPGV 924
>XP_005250082
          Length = 4983

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IRAVVLPGV 9
           I AVVLPGV
Sbjct: 917 IGAVVLPGV 925
>NP_056261
          Length = 2275

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IRAVVLPG 8
           ++AVVLPG
Sbjct: 126 VKAVVLPG 133
>XP_006711822
          Length = 2266

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IRAVVLPG 8
           ++AVVLPG
Sbjct: 117 VKAVVLPG 124
>XP_006711821
          Length = 2301

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IRAVVLPG 8
           ++AVVLPG
Sbjct: 152 VKAVVLPG 159
>NP_065883
          Length = 1237

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RAVVLPG 8
           +AVVLPG
Sbjct: 422 KAVVLPG 428
>NP_060718
          Length = 605

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  IRAVVLPG 8
          IRA VLPG
Sbjct: 14 IRARVLPG 21
>XP_005245423
          Length = 1246

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RAVVLPG 8
           +AVVLPG
Sbjct: 431 KAVVLPG 437
>XP_005245425
          Length = 1299

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RAVVLPG 8
           +AVVLPG
Sbjct: 484 KAVVLPG 490
>NP_001034484
          Length = 334

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IRAVVLPGV 9
          IRA+  PGV
Sbjct: 11 IRAISCPGV 19
>NP_001271254
          Length = 352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IRAVVLPGV 9
           +  V+LPGV
Sbjct: 248 LNGVILPGV 256
>NP_001181
          Length = 392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IRAVVLPGV 9
           +  V+LPGV
Sbjct: 288 LNGVILPGV 296
>NP_001158245
          Length = 300

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IRAVVLPGV 9
           +  V+LPGV
Sbjct: 196 LNGVILPGV 204
>NP_078836
          Length = 686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  IRAVVLPG 8
          +RA+V+PG
Sbjct: 34 LRALVVPG 41
>XP_005269208
          Length = 455

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  IRAVVLPG 8
          +RA+V+PG
Sbjct: 34 LRALVVPG 41
>XP_005269207
          Length = 685

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  IRAVVLPG 8
          +RA+V+PG
Sbjct: 34 LRALVVPG 41
>XP_005251556
          Length = 326

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IRAVVLPGV 9
          IRA+  PGV
Sbjct: 11 IRAISCPGV 19
>XP_006716862
          Length = 392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IRAVVLPGV 9
          IRA+  PGV
Sbjct: 11 IRAISCPGV 19
>XP_006716861
          Length = 406

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IRAVVLPGV 9
          IRA+  PGV
Sbjct: 11 IRAISCPGV 19
>XP_006716860
          Length = 406

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IRAVVLPGV 9
          IRA+  PGV
Sbjct: 11 IRAISCPGV 19
>XP_006716859
          Length = 406

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IRAVVLPGV 9
          IRA+  PGV
Sbjct: 11 IRAISCPGV 19
>XP_006716858
          Length = 406

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IRAVVLPGV 9
          IRA+  PGV
Sbjct: 11 IRAISCPGV 19
>NP_775960
          Length = 1285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AVVLPG 8
           AVVLPG
Sbjct: 714 AVVLPG 719
>XP_005251991
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   AVVLPG 8
           AVVLPG
Sbjct: 382 AVVLPG 387
>NP_001243643
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  AVVLPG 8
          AV+LPG
Sbjct: 92 AVILPG 97
>NP_002151
          Length = 2201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1126 LRAVDIPGL 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1399 LRAVDIPGL 1407
>NP_001164434
          Length = 242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   AVVLPGV 9
           A+V+PG+
Sbjct: 233 AIVVPGI 239
>NP_570123
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IRAVVLPGV 9
           +++V+LP V
Sbjct: 471 VKSVILPSV 479
>NP_991402
          Length = 242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   AVVLPGV 9
           A+V+PG+
Sbjct: 233 AIVVPGI 239
>XP_006717164
          Length = 1655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1126 LRAVDIPGL 1134
>XP_005252030
          Length = 1837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1126 LRAVDIPGL 1134
>XP_006717163
          Length = 1928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1126 LRAVDIPGL 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1399 LRAVDIPGL 1407
>XP_006717162
          Length = 1928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1126 LRAVDIPGL 1134
>XP_006717161
          Length = 2019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1126 LRAVDIPGL 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1308 LRAVDIPGL 1316
>XP_006717160
          Length = 2110

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1126 LRAVDIPGL 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1308 LRAVDIPGL 1316
>XP_005252029
          Length = 2110

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1126 LRAVDIPGL 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1399 LRAVDIPGL 1407
>XP_006717159
          Length = 2293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1126 LRAVDIPGL 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IRAVVLPGV 9
            +RAV +PG+
Sbjct: 1399 LRAVDIPGL 1407
>XP_006714594
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IRAVVLPGV 9
           +++V+LP V
Sbjct: 443 VKSVILPSV 451
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.154    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 686,354
Number of extensions: 692
Number of successful extensions: 51
Number of sequences better than 10000.0: 45
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package