Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           18    1482
NP_000242                                                              18    1482
XP_005264389                                                           18    1482
NP_115532                                                              16    5631
NP_076414                                                              16    5631
NP_001002259                                                           16    5631
NP_001193785                                                           16    5631
XP_006719210                                                           16    5631
XP_006719209                                                           16    5631
XP_006719208                                                           16    5631
XP_006719207                                                           16    5631
XP_006719206                                                           16    5631
XP_006719205                                                           16    5631
XP_006719204                                                           16    5631
XP_006719203                                                           16    5631
XP_006719202                                                           16    5631
XP_006719201                                                           16    5631
XP_006719200                                                           16    5631
NP_149091                                                              16    7355
>NP_001245210
          Length = 868

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IQSTLISAA 9
           +QSTLISAA
Sbjct: 426 MQSTLISAA 434
>NP_000242
          Length = 934

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IQSTLISAA 9
           +QSTLISAA
Sbjct: 492 MQSTLISAA 500
>XP_005264389
          Length = 921

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IQSTLISAA 9
           +QSTLISAA
Sbjct: 492 MQSTLISAA 500
>NP_115532
          Length = 960

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>NP_076414
          Length = 1077

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>NP_001002259
          Length = 1127

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>NP_001193785
          Length = 905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>XP_006719210
          Length = 940

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>XP_006719209
          Length = 941

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>XP_006719208
          Length = 961

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>XP_006719207
          Length = 1043

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>XP_006719206
          Length = 1046

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  IQSTLISAA 9
          +QSTL SAA
Sbjct: 23 LQSTLSSAA 31
>XP_006719205
          Length = 1057

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>XP_006719204
          Length = 1078

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>XP_006719203
          Length = 1091

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>XP_006719202
          Length = 1092

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>XP_006719201
          Length = 1106

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>XP_006719200
          Length = 1126

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IQSTLISAA 9
           +QSTL SAA
Sbjct: 104 LQSTLSSAA 112
>NP_149091
          Length = 859

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IQSTLIS 7
           +QSTLIS
Sbjct: 836 VQSTLIS 842
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.115    0.247 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 242,681
Number of extensions: 192
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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