Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              18    1935
NP_444254                                                              18    1935
NP_444253                                                              18    1935
NP_444255                                                              18    1935
XP_005247551                                                           18    1935
XP_005247550                                                           18    1935
XP_006713712                                                           18    1935
XP_005247549                                                           18    1935
NP_003417                                                              16    5631
NP_001243453                                                           16    5631
NP_001243454                                                           16    5631
NP_689691                                                              16    5631
NP_653295                                                              16    5631
XP_005258624                                                           16    5631
XP_005258622                                                           16    5631
XP_005258616                                                           16    5631
XP_005258615                                                           16    5631
NP_001153332                                                           16    5631
NP_001153333                                                           16    5631
NP_057409                                                              16    7355
NP_598009                                                              16    7355
NP_001265663                                                           16    7355
NP_057408                                                              16    7355
NP_001265539                                                           16    7355
NP_002457                                                              16    7355
NP_002709                                                              15    9605
NP_001103132                                                           15    9605
NP_689697                                                              15    9605
NP_061122                                                              15    9605
NP_872579                                                              15    9605
XP_005258621                                                           15    9605
XP_006723112                                                           15    9605
XP_006723111                                                           15    9605
XP_006723110                                                           15    9605
XP_006723109                                                           15    9605
XP_005257215                                                           15    9605
XP_005257214                                                           15    9605
XP_005257213                                                           15    9605
XP_005257212                                                           15    9605
XP_006721834                                                           15    9605
XP_005257211                                                           15    9605
XP_005257210                                                           15    9605
XP_005257209                                                           15    9605
XP_005257208                                                           15    9605
XP_006721833                                                           15    9605
XP_005257207                                                           15    9605
XP_006720668                                                           15    9605
XP_006720667                                                           15    9605
XP_006713749                                                           15    9605
NP_001033729                                                           15    9605
>NP_444256
          Length = 1794

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IQSSSLTLS 9
            I+SSSLTLS
Sbjct: 1274 IRSSSLTLS 1282
>NP_444254
          Length = 1845

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IQSSSLTLS 9
            I+SSSLTLS
Sbjct: 1274 IRSSSLTLS 1282
>NP_444253
          Length = 1914

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IQSSSLTLS 9
            I+SSSLTLS
Sbjct: 1343 IRSSSLTLS 1351
>NP_444255
          Length = 1863

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IQSSSLTLS 9
            I+SSSLTLS
Sbjct: 1343 IRSSSLTLS 1351
>XP_005247551
          Length = 1855

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IQSSSLTLS 9
            I+SSSLTLS
Sbjct: 1284 IRSSSLTLS 1292
>XP_005247550
          Length = 1856

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IQSSSLTLS 9
            I+SSSLTLS
Sbjct: 1353 IRSSSLTLS 1361
>XP_006713712
          Length = 1923

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IQSSSLTLS 9
            I+SSSLTLS
Sbjct: 1353 IRSSSLTLS 1361
>XP_005247549
          Length = 1924

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IQSSSLTLS 9
            I+SSSLTLS
Sbjct: 1353 IRSSSLTLS 1361
>NP_003417
          Length = 644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLTL
Sbjct: 259 QSSSLTL 265
>NP_001243453
          Length = 644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLTL
Sbjct: 259 QSSSLTL 265
>NP_001243454
          Length = 573

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLTL
Sbjct: 188 QSSSLTL 194
>NP_689691
          Length = 569

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLTL
Sbjct: 223 QSSSLTL 229
>NP_653295
          Length = 536

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLTL
Sbjct: 229 QSSSLTL 235
>XP_005258624
          Length = 333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2  QSSSLTL 8
          QSSSLTL
Sbjct: 26 QSSSLTL 32
>XP_005258622
          Length = 592

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLTL
Sbjct: 285 QSSSLTL 291
>XP_005258616
          Length = 526

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLTL
Sbjct: 180 QSSSLTL 186
>XP_005258615
          Length = 570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLTL
Sbjct: 224 QSSSLTL 230
>NP_001153332
          Length = 569

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLTL
Sbjct: 223 QSSSLTL 229
>NP_001153333
          Length = 569

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLTL
Sbjct: 223 QSSSLTL 229
>NP_057409
          Length = 621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IQSSSLT 7
           +QSSSLT
Sbjct: 513 VQSSSLT 519
>NP_598009
          Length = 653

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IQSSSLT 7
           +QSSSLT
Sbjct: 545 VQSSSLT 551
>NP_001265663
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IQSSSLT 7
           +QSSSLT
Sbjct: 503 VQSSSLT 509
>NP_057408
          Length = 548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IQSSSLT 7
           +QSSSLT
Sbjct: 440 VQSSSLT 446
>NP_001265539
          Length = 676

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SSSLTLS 9
           SSSLTLS
Sbjct: 592 SSSLTLS 598
>NP_002457
          Length = 700

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SSSLTLS 9
           SSSLTLS
Sbjct: 616 SSSLTLS 622
>NP_002709
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IQSSSLTLS 9
           +QS SLT++
Sbjct: 393 VQSQSLTMN 401
>NP_001103132
          Length = 4284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    IQSSSLTL 8
            +QSSSL+L
Sbjct: 3950 LQSSSLSL 3957
>NP_689697
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLT+
Sbjct: 617 QSSSLTI 623
>NP_061122
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  IQSSSLTLS 9
          ++SSS+T+S
Sbjct: 78 LESSSVTIS 86
>NP_872579
          Length = 2920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IQSSSLTLS 9
            +QSS+ TLS
Sbjct: 2397 VQSSTQTLS 2405
>XP_005258621
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLT+
Sbjct: 458 QSSSLTI 464
>XP_006723112
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLT+
Sbjct: 617 QSSSLTI 623
>XP_006723111
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLT+
Sbjct: 641 QSSSLTI 647
>XP_006723110
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLT+
Sbjct: 641 QSSSLTI 647
>XP_006723109
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSSSLTL 8
           QSSSLT+
Sbjct: 641 QSSSLTI 647
>XP_005257215
          Length = 3032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IQSSSLTLS 9
            +QSS+ TLS
Sbjct: 2451 VQSSTQTLS 2459
>XP_005257214
          Length = 3094

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IQSSSLTLS 9
            +QSS+ TLS
Sbjct: 2513 VQSSTQTLS 2521
>XP_005257213
          Length = 3095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IQSSSLTLS 9
            +QSS+ TLS
Sbjct: 2514 VQSSTQTLS 2522
>XP_005257212
          Length = 3095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IQSSSLTLS 9
            +QSS+ TLS
Sbjct: 2514 VQSSTQTLS 2522
>XP_006721834
          Length = 3100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IQSSSLTLS 9
            +QSS+ TLS
Sbjct: 2577 VQSSTQTLS 2585
>XP_005257211
          Length = 3100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IQSSSLTLS 9
            +QSS+ TLS
Sbjct: 2577 VQSSTQTLS 2585
>XP_005257210
          Length = 3104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IQSSSLTLS 9
            +QSS+ TLS
Sbjct: 2523 VQSSTQTLS 2531
>XP_005257209
          Length = 3148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IQSSSLTLS 9
            +QSS+ TLS
Sbjct: 2577 VQSSTQTLS 2585
>XP_005257208
          Length = 3157

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IQSSSLTLS 9
            +QSS+ TLS
Sbjct: 2576 VQSSTQTLS 2584
>XP_006721833
          Length = 3158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IQSSSLTLS 9
            +QSS+ TLS
Sbjct: 2577 VQSSTQTLS 2585
>XP_005257207
          Length = 3158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IQSSSLTLS 9
            +QSS+ TLS
Sbjct: 2577 VQSSTQTLS 2585
>XP_006720668
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  IQSSSLTLS 9
          ++SSS+T+S
Sbjct: 78 LESSSVTIS 86
>XP_006720667
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  IQSSSLTLS 9
          ++SSS+T+S
Sbjct: 78 LESSSVTIS 86
>XP_006713749
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IQSSSLTLS 9
           +QS SLT++
Sbjct: 393 VQSQSLTMN 401
>NP_001033729
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  IQSSSLTLS 9
          ++SSS+T+S
Sbjct: 78 LESSSVTIS 86
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.294    0.105    0.214 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 288,891
Number of extensions: 350
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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