Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055146                                                              17    2528
NP_000880                                                              17    2528
XP_006719439                                                           17    2528
XP_005268909                                                           17    2528
XP_005268908                                                           17    2528
XP_005262932                                                           17    2528
NP_079058                                                              17    3301
NP_001073890                                                           17    3301
XP_006722755                                                           17    3301
NP_001074011                                                           17    4312
NP_055782                                                              16    5631
XP_006725604                                                           16    5631
XP_006725603                                                           16    5631
XP_006725602                                                           16    5631
XP_006725601                                                           16    5631
XP_006725600                                                           16    5631
XP_005254293                                                           16    5631
XP_005254289                                                           16    5631
XP_005254292                                                           16    5631
XP_005254291                                                           16    5631
XP_005254290                                                           16    5631
XP_006719941                                                           16    5631
XP_006719940                                                           16    5631
NP_113619                                                              16    5631
NP_060170                                                              15    9605
NP_001069                                                              15    9605
NP_001186763                                                           15    9605
NP_542413                                                              15    9605
NP_001229658                                                           15    9605
NP_000410                                                              15    9605
NP_071434                                                              15    9605
NP_001123520                                                           15    9605
NP_001123521                                                           15    9605
NP_001123522                                                           15    9605
NP_056111                                                              15    9605
NP_006124                                                              15    9605
XP_006720005                                                           15    9605
XP_006720004                                                           15    9605
XP_005254093                                                           15    9605
XP_006720003                                                           15    9605
XP_006720002                                                           15    9605
XP_005254092                                                           15    9605
XP_006720001                                                           15    9605
XP_006720000                                                           15    9605
XP_005254091                                                           15    9605
XP_006719999                                                           15    9605
XP_006719998                                                           15    9605
XP_006719997                                                           15    9605
XP_006719996                                                           15    9605
XP_006719995                                                           15    9605
XP_006719994                                                           15    9605
XP_006719993                                                           15    9605
XP_006719992                                                           15    9605
XP_006719991                                                           15    9605
XP_006719990                                                           15    9605
XP_006719989                                                           15    9605
XP_006719988                                                           15    9605
XP_006719987                                                           15    9605
XP_006719986                                                           15    9605
XP_006719985                                                           15    9605
XP_005274287                                                           15    9605
NP_006647                                                              15    9605
>NP_055146
          Length = 501

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           IQC + ELA
Sbjct: 156 IQCEIPELA 164
>NP_000880
          Length = 798

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QCSVAELA 9
           +CSVAEL+
Sbjct: 512 ECSVAELS 519
>XP_006719439
          Length = 782

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QCSVAELA 9
           +CSVAEL+
Sbjct: 512 ECSVAELS 519
>XP_005268909
          Length = 798

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QCSVAELA 9
           +CSVAEL+
Sbjct: 512 ECSVAELS 519
>XP_005268908
          Length = 798

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QCSVAELA 9
           +CSVAEL+
Sbjct: 512 ECSVAELS 519
>XP_005262932
          Length = 342

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           IQC + ELA
Sbjct: 156 IQCEIPELA 164
>NP_079058
          Length = 299

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           +QC V ELA
Sbjct: 146 LQCQVRELA 154
>NP_001073890
          Length = 1703

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    QCSVAELA 9
            QC+V ELA
Sbjct: 1458 QCAVVELA 1465
>XP_006722755
          Length = 1722

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    QCSVAELA 9
            QC+V ELA
Sbjct: 1458 QCAVVELA 1465
>NP_001074011
          Length = 1133

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IQCSVAEL 8
           +QCS AEL
Sbjct: 571 LQCSPAEL 578
>NP_055782
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           + CSV ELA
Sbjct: 810 VLCSVEELA 818
>XP_006725604
          Length = 904

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           + CSV ELA
Sbjct: 810 VLCSVEELA 818
>XP_006725603
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           + CSV ELA
Sbjct: 810 VLCSVEELA 818
>XP_006725602
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           + CSV ELA
Sbjct: 810 VLCSVEELA 818
>XP_006725601
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           + CSV ELA
Sbjct: 810 VLCSVEELA 818
>XP_006725600
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           + CSV ELA
Sbjct: 810 VLCSVEELA 818
>XP_005254293
          Length = 904

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           + CSV ELA
Sbjct: 810 VLCSVEELA 818
>XP_005254289
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           + CSV ELA
Sbjct: 810 VLCSVEELA 818
>XP_005254292
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           + CSV ELA
Sbjct: 810 VLCSVEELA 818
>XP_005254291
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           + CSV ELA
Sbjct: 810 VLCSVEELA 818
>XP_005254290
          Length = 1017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           + CSV ELA
Sbjct: 810 VLCSVEELA 818
>XP_006719941
          Length = 699

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IQCSVAEL 8
           I C+VAEL
Sbjct: 218 IACTVAEL 225
>XP_006719940
          Length = 820

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IQCSVAEL 8
           I C+VAEL
Sbjct: 347 IACTVAEL 354
>NP_113619
          Length = 828

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IQCSVAEL 8
           I C+VAEL
Sbjct: 347 IACTVAEL 354
>NP_060170
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  QCSVAE 7
          +CSVAE
Sbjct: 73 ECSVAE 78
>NP_001069
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   IQCSVAEL 8
           ++CSVA++
Sbjct: 135 VKCSVADV 142
>NP_001186763
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  IQCSVAEL 8
          ++CSVA++
Sbjct: 73 VKCSVADV 80
>NP_542413
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   IQCSVAEL 8
           ++CSVA++
Sbjct: 135 VKCSVADV 142
>NP_001229658
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  QCSVAE 7
          +CSVAE
Sbjct: 73 ECSVAE 78
>NP_000410
          Length = 1039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   IQCSVAELA 9
           +QC + E+A
Sbjct: 919 VQCDLQEMA 927
>NP_071434
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  CSVAEL 8
          CSVAE+
Sbjct: 30 CSVAEI 35
>NP_001123520
          Length = 2068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 378 LQCCVAE 384
>NP_001123521
          Length = 1254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 379 LQCCVAE 385
>NP_001123522
          Length = 1253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 378 LQCCVAE 384
>NP_056111
          Length = 2069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 379 LQCCVAE 385
>NP_006124
          Length = 1042

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  IQCSVAELA 9
          + C +AE+A
Sbjct: 67 LSCMIAEMA 75
>XP_006720005
          Length = 1126

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_006720004
          Length = 1412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_005254093
          Length = 2046

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 379 LQCCVAE 385
>XP_006720003
          Length = 2058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 307 LQCCVAE 313
>XP_006720002
          Length = 2058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 307 LQCCVAE 313
>XP_005254092
          Length = 2062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 379 LQCCVAE 385
>XP_006720001
          Length = 2073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_006720000
          Length = 2084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 379 LQCCVAE 385
>XP_005254091
          Length = 2093

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 379 LQCCVAE 385
>XP_006719999
          Length = 2095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_006719998
          Length = 2103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_006719997
          Length = 2104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_006719996
          Length = 2104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_006719995
          Length = 2106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 378 LQCCVAE 384
>XP_006719994
          Length = 2107

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 379 LQCCVAE 385
>XP_006719993
          Length = 2110

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_006719992
          Length = 2116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_006719991
          Length = 2118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_006719990
          Length = 2118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_006719989
          Length = 2127

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_006719988
          Length = 2129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 378 LQCCVAE 384
>XP_006719987
          Length = 2130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 379 LQCCVAE 385
>XP_006719986
          Length = 2139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_006719985
          Length = 2141

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   IQCSVAE 7
           +QC VAE
Sbjct: 390 LQCCVAE 396
>XP_005274287
          Length = 1042

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  IQCSVAELA 9
          + C +AE+A
Sbjct: 67 LSCMIAEMA 75
>NP_006647
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   IQCSVAEL 8
           ++C VAE+
Sbjct: 257 VECEVAEV 264
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.126    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 599,243
Number of extensions: 543
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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