Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     299
NP_000304                                                              17    2528
NP_001258949                                                           17    2528
NP_067050                                                              17    2528
NP_001254747                                                           17    2528
XP_003960168                                                           17    2528
XP_006720386                                                           17    2528
XP_006720385                                                           17    2528
XP_005268275                                                           17    2528
XP_005247683                                                           17    2528
XP_934596                                                              17    2528
XP_001722188                                                           17    2528
NP_570843                                                              17    4312
NP_001128529                                                           17    4312
NP_001138913                                                           17    4312
NP_060734                                                              17    4312
NP_001138912                                                           17    4312
NP_037499                                                              17    4312
NP_001138424                                                           17    4312
NP_001175                                                              16    5631
NP_060264                                                              16    5631
NP_055108                                                              16    5631
XP_006722754                                                           16    5631
XP_005259877                                                           16    5631
XP_005251551                                                           16    5631
XP_006716857                                                           16    5631
NP_055790                                                              16    5631
NP_003310                                                              16    7355
NP_597676                                                              16    7355
NP_001243779                                                           16    7355
NP_596869                                                              16    7355
NP_009153                                                              16    7355
NP_001017926                                                           16    7355
NP_001136326                                                           16    7355
XP_006725462                                                           16    7355
XP_005261245                                                           16    7355
XP_005246888                                                           16    7355
XP_006712788                                                           16    7355
XP_006712787                                                           16    7355
XP_006712786                                                           16    7355
XP_006710739                                                           16    7355
XP_005270979                                                           16    7355
NP_056972                                                              16    7355
NP_001254479                                                           16    7355
NP_597681                                                              16    7355
NP_072179                                                              15    9605
NP_002881                                                              15    9605
NP_115495                                                              15    9605
NP_000882                                                              15    9605
NP_001125                                                              15    9605
NP_001127878                                                           15    9605
NP_001127877                                                           15    9605
NP_001121620                                                           15    9605
NP_612147                                                              15    9605
NP_115950                                                              15    9605
NP_001193991                                                           15    9605
XP_006724402                                                           15    9605
XP_005261842                                                           15    9605
XP_005261841                                                           15    9605
XP_005261840                                                           15    9605
XP_005261839                                                           15    9605
XP_005261838                                                           15    9605
XP_005250213                                                           15    9605
NP_064621                                                              15    9605
NP_003225                                                              15    9605
>NP_722576
          Length = 3080

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  IPELNRFTA 9
          IPEL+RFTA
Sbjct: 49 IPELSRFTA 57
>NP_000304
          Length = 676

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPELNRFTA 9
           +PE++RF+A
Sbjct: 317 LPEISRFSA 325
>NP_001258949
          Length = 637

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PELNRFTA 9
           PEL RFTA
Sbjct: 473 PELIRFTA 480
>NP_067050
          Length = 149

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IPELNRF 7
           IP+LNRF
Sbjct: 112 IPKLNRF 118
>NP_001254747
          Length = 171

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IPELNRF 7
           IP+LNRF
Sbjct: 112 IPKLNRF 118
>XP_003960168
          Length = 147

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IPELNRF 7
           IP+LNRF
Sbjct: 110 IPKLNRF 116
>XP_006720386
          Length = 1571

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    PELNRFTA 9
            PEL RFTA
Sbjct: 1407 PELIRFTA 1414
>XP_006720385
          Length = 1683

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    PELNRFTA 9
            PEL RFTA
Sbjct: 1519 PELIRFTA 1526
>XP_005268275
          Length = 1684

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    PELNRFTA 9
            PEL RFTA
Sbjct: 1520 PELIRFTA 1527
>XP_005247683
          Length = 708

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPELNRFTA 9
           +PE++RF+A
Sbjct: 349 LPEISRFSA 357
>XP_934596
          Length = 147

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IPELNRF 7
           IP+LNRF
Sbjct: 110 IPKLNRF 116
>XP_001722188
          Length = 147

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IPELNRF 7
           IP+LNRF
Sbjct: 110 IPKLNRF 116
>NP_570843
          Length = 581

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPELNRFT 8
           +P+LNR T
Sbjct: 268 LPQLNRLT 275
>NP_001128529
          Length = 587

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPELNRFT 8
           +P+LNR T
Sbjct: 274 LPQLNRLT 281
>NP_001138913
          Length = 471

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   PELNRF 7
           PE+NRF
Sbjct: 266 PEINRF 271
>NP_060734
          Length = 732

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   PELNRF 7
           PE+NRF
Sbjct: 492 PEINRF 497
>NP_001138912
          Length = 668

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   PELNRF 7
           PE+NRF
Sbjct: 428 PEINRF 433
>NP_037499
          Length = 808

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPELNRFT 8
           +PELN+ T
Sbjct: 434 LPELNKMT 441
>NP_001138424
          Length = 2172

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    IPELNRFT 8
            +P+LN FT
Sbjct: 1058 VPDLNPFT 1065
>NP_001175
          Length = 2644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   PELNRF 7
           P+LNRF
Sbjct: 985 PDLNRF 990
>NP_060264
          Length = 1801

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   PELNRFTA 9
           PEL RF A
Sbjct: 559 PELQRFMA 566
>NP_055108
          Length = 500

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IPELNRFTA 9
           +PEL  FTA
Sbjct: 313 LPELYAFTA 321
>XP_006722754
          Length = 1169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PELNRFTA 9
           PE+ RF+A
Sbjct: 370 PEIKRFSA 377
>XP_005259877
          Length = 1394

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PELNRFTA 9
           PE+ RF+A
Sbjct: 595 PEIKRFSA 602
>XP_005251551
          Length = 1801

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   PELNRFTA 9
           PEL RF A
Sbjct: 559 PELQRFMA 566
>XP_006716857
          Length = 1834

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   PELNRFTA 9
           PEL RF A
Sbjct: 592 PELQRFMA 599
>NP_055790
          Length = 1570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PELNRFTA 9
           PE+ RF+A
Sbjct: 771 PEIKRFSA 778
>NP_003310
          Length = 26926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1     IPELNRF 7
             IPE NR+
Sbjct: 14337 IPECNRY 14343
>NP_597676
          Length = 27051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1     IPELNRF 7
             IPE NR+
Sbjct: 14462 IPECNRY 14468
>NP_001243779
          Length = 34350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1     IPELNRF 7
             IPE NR+
Sbjct: 21761 IPECNRY 21767
>NP_596869
          Length = 33423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1     IPELNRF 7
             IPE NR+
Sbjct: 20834 IPECNRY 20840
>NP_009153
          Length = 873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  PELNRFT 8
          P+LN FT
Sbjct: 80 PDLNMFT 86
>NP_001017926
          Length = 873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  PELNRFT 8
          P+LN FT
Sbjct: 80 PDLNMFT 86
>NP_001136326
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  IPELNRFTA 9
          +P+  RFT+
Sbjct: 65 VPDFGRFTS 73
>XP_006725462
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  IPELNRFTA 9
          +P+  RFT+
Sbjct: 65 VPDFGRFTS 73
>XP_005261245
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  IPELNRFTA 9
          +P+  RFT+
Sbjct: 65 VPDFGRFTS 73
>XP_005246888
          Length = 22663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1     IPELNRF 7
             IPE NR+
Sbjct: 10074 IPECNRY 10080
>XP_006712788
          Length = 24022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1     IPELNRF 7
             IPE NR+
Sbjct: 11433 IPECNRY 11439
>XP_006712787
          Length = 33978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1     IPELNRF 7
             IPE NR+
Sbjct: 21389 IPECNRY 21395
>XP_006712786
          Length = 35484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1     IPELNRF 7
             IPE NR+
Sbjct: 22895 IPECNRY 22901
>XP_006710739
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPELNRFT 8
           IP+LN+ T
Sbjct: 102 IPDLNQIT 109
>XP_005270979
          Length = 728

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPELNRFT 8
           IP+LN+ T
Sbjct: 102 IPDLNQIT 109
>NP_056972
          Length = 728

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPELNRFT 8
           IP+LN+ T
Sbjct: 102 IPDLNQIT 109
>NP_001254479
          Length = 35991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1     IPELNRF 7
             IPE NR+
Sbjct: 23402 IPECNRY 23408
>NP_597681
          Length = 27118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1     IPELNRF 7
             IPE NR+
Sbjct: 14529 IPECNRY 14535
>NP_072179
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   PELNRF 7
           P++NRF
Sbjct: 472 PDINRF 477
>NP_002881
          Length = 1047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   PELNRF 7
           P++NRF
Sbjct: 649 PDINRF 654
>NP_115495
          Length = 6306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1    IPELNRF 7
            IPE N F
Sbjct: 1196 IPEFNEF 1202
>NP_000882
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IPELNRFTA 9
           + E+N FTA
Sbjct: 123 VSEVNSFTA 131
>NP_001125
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 2   PELNRF 7
           P LNRF
Sbjct: 328 PNLNRF 333
>NP_001127878
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  PELNRFTA 9
          PE N F A
Sbjct: 61 PEFNNFAA 68
>NP_001127877
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  PELNRFTA 9
          PE N F A
Sbjct: 61 PEFNNFAA 68
>NP_001121620
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   IPELNR 6
           IPELN+
Sbjct: 580 IPELNK 585
>NP_612147
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  PELNRFTA 9
          PE N F A
Sbjct: 61 PEFNNFAA 68
>NP_115950
          Length = 217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   PELNRF 7
           PEL+RF
Sbjct: 153 PELDRF 158
>NP_001193991
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   PELNRF 7
           PEL+RF
Sbjct: 132 PELDRF 137
>XP_006724402
          Length = 129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  PELNRF 7
          PEL+RF
Sbjct: 55 PELDRF 60
>XP_005261842
          Length = 166

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  PELNRF 7
          PEL+RF
Sbjct: 92 PELDRF 97
>XP_005261841
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   PELNRF 7
           PEL+RF
Sbjct: 132 PELDRF 137
>XP_005261840
          Length = 206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   PELNRF 7
           PEL+RF
Sbjct: 132 PELDRF 137
>XP_005261839
          Length = 227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   PELNRF 7
           PEL+RF
Sbjct: 153 PELDRF 158
>XP_005261838
          Length = 227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   PELNRF 7
           PEL+RF
Sbjct: 153 PELDRF 158
>XP_005250213
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  PELNRFTA 9
          PE N F A
Sbjct: 61 PEFNNFAA 68
>NP_064621
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   IPELNR 6
           +PELNR
Sbjct: 204 MPELNR 209
>NP_003225
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   IPELNR 6
           IPELN+
Sbjct: 580 IPELNK 585
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.141    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 659,043
Number of extensions: 1355
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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