Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001895                                                              19     869
NP_001091680                                                           19     869
NP_001091679                                                           19     869
XP_006713048                                                           19     869
XP_006713047                                                           19     869
XP_006713046                                                           19     869
XP_005264943                                                           19     869
NP_002221                                                              18    1482
NP_068831                                                              18    1482
XP_006721941                                                           18    1482
XP_006721940                                                           18    1482
XP_006721939                                                           18    1482
XP_006721938                                                           18    1482
XP_006721937                                                           18    1482
XP_006721936                                                           18    1482
XP_006721935                                                           18    1482
XP_006721934                                                           18    1482
XP_005257370                                                           18    1482
NP_036531                                                              17    4312
NP_001271207                                                           17    4312
NP_001271206                                                           17    4312
XP_005264554                                                           17    4312
XP_005264553                                                           17    4312
NP_055640                                                              16    5631
XP_006714348                                                           16    5631
XP_006714347                                                           16    5631
NP_001093896                                                           16    5631
NP_001093898                                                           16    5631
NP_066982                                                              16    5631
NP_001093897                                                           16    5631
NP_001093899                                                           16    5631
NP_653251                                                              15    9605
>NP_001895
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPALVKML
Sbjct: 237 IPALVKML 244
>NP_001091680
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPALVKML
Sbjct: 237 IPALVKML 244
>NP_001091679
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPALVKML
Sbjct: 237 IPALVKML 244
>XP_006713048
          Length = 720

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPALVKML
Sbjct: 237 IPALVKML 244
>XP_006713047
          Length = 774

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPALVKML
Sbjct: 230 IPALVKML 237
>XP_006713046
          Length = 774

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPALVKML
Sbjct: 230 IPALVKML 237
>XP_005264943
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPALVKML
Sbjct: 237 IPALVKML 244
>NP_002221
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IPALVKMLA 9
           IPALV+ML+
Sbjct: 228 IPALVRMLS 236

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPA+VK+L
Sbjct: 482 IPAIVKLL 489
>NP_068831
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IPALVKMLA 9
           IPALV+ML+
Sbjct: 228 IPALVRMLS 236

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPA+VK+L
Sbjct: 482 IPAIVKLL 489
>XP_006721941
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IPALVKMLA 9
           IPALV+ML+
Sbjct: 228 IPALVRMLS 236

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPA+VK+L
Sbjct: 482 IPAIVKLL 489
>XP_006721940
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IPALVKMLA 9
           IPALV+ML+
Sbjct: 228 IPALVRMLS 236

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPA+VK+L
Sbjct: 482 IPAIVKLL 489
>XP_006721939
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IPALVKMLA 9
           IPALV+ML+
Sbjct: 228 IPALVRMLS 236

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPA+VK+L
Sbjct: 482 IPAIVKLL 489
>XP_006721938
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IPALVKMLA 9
           IPALV+ML+
Sbjct: 228 IPALVRMLS 236

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPA+VK+L
Sbjct: 482 IPAIVKLL 489
>XP_006721937
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IPALVKMLA 9
           IPALV+ML+
Sbjct: 228 IPALVRMLS 236

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPA+VK+L
Sbjct: 482 IPAIVKLL 489
>XP_006721936
          Length = 745

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IPALVKMLA 9
           IPALV+ML+
Sbjct: 228 IPALVRMLS 236

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPA+VK+L
Sbjct: 482 IPAIVKLL 489
>XP_006721935
          Length = 762

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IPALVKMLA 9
           IPALV+ML+
Sbjct: 245 IPALVRMLS 253

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPA+VK+L
Sbjct: 499 IPAIVKLL 506
>XP_006721934
          Length = 783

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IPALVKMLA 9
           IPALV+ML+
Sbjct: 266 IPALVRMLS 274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPA+VK+L
Sbjct: 520 IPAIVKLL 527
>XP_005257370
          Length = 783

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IPALVKMLA 9
           IPALV+ML+
Sbjct: 266 IPALVRMLS 274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IPALVKML 8
           IPA+VK+L
Sbjct: 520 IPAIVKLL 527
>NP_036531
          Length = 271

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  IPALVKMLA 9
          +PA V+M+A
Sbjct: 68 VPAFVRMIA 76
>NP_001271207
          Length = 273

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  IPALVKMLA 9
          +PA V+M+A
Sbjct: 70 VPAFVRMIA 78
>NP_001271206
          Length = 272

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  IPALVKMLA 9
          +PA V+M+A
Sbjct: 68 VPAFVRMIA 76
>XP_005264554
          Length = 330

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPALVKMLA 9
           +PAL+KM++
Sbjct: 311 VPALLKMVS 319
>XP_005264553
          Length = 330

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPALVKMLA 9
           +PAL+KM++
Sbjct: 311 VPALLKMVS 319
>NP_055640
          Length = 2271

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    PALVKMLA 9
            P LVK+LA
Sbjct: 1038 PVLVKLLA 1045
>XP_006714348
          Length = 478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  IPALVKML 8
          IP LVK+L
Sbjct: 53 IPTLVKLL 60
>XP_006714347
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IPALVKML 8
           IP LVK+L
Sbjct: 102 IPTLVKLL 109
>NP_001093896
          Length = 608

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IPALVKML 8
           IP LVK+L
Sbjct: 183 IPTLVKLL 190
>NP_001093898
          Length = 559

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IPALVKML 8
           IP LVK+L
Sbjct: 134 IPTLVKLL 141
>NP_066982
          Length = 607

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IPALVKML 8
           IP LVK+L
Sbjct: 183 IPTLVKLL 190
>NP_001093897
          Length = 607

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IPALVKML 8
           IP LVK+L
Sbjct: 182 IPTLVKLL 189
>NP_001093899
          Length = 558

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IPALVKML 8
           IP LVK+L
Sbjct: 133 IPTLVKLL 140
>NP_653251
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IPALVK 6
           IPALVK
Sbjct: 430 IPALVK 435
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.142    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 381,323
Number of extensions: 387
Number of successful extensions: 43
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 43
Number of HSP's successfully gapped: 43
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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