Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     509
XP_005262424                                                           20     509
NP_116176                                                              18    1935
XP_005247896                                                           18    1935
XP_006713857                                                           18    1935
NP_919227                                                              17    3301
NP_001693                                                              17    4312
XP_005251072                                                           17    4312
XP_006710853                                                           16    5631
XP_006710852                                                           16    5631
XP_006710851                                                           16    5631
XP_006710850                                                           16    5631
XP_006710849                                                           16    5631
XP_005271124                                                           16    5631
XP_006710848                                                           16    5631
XP_006710847                                                           16    5631
XP_006710846                                                           16    5631
NP_001694                                                              16    5631
NP_056051                                                              16    7355
XP_006714219                                                           16    7355
XP_006714218                                                           16    7355
XP_006714217                                                           16    7355
XP_006714216                                                           16    7355
NP_008862                                                              15    9605
NP_001243412                                                           15    9605
NP_001243411                                                           15    9605
NP_001970                                                              15    9605
NP_001243413                                                           15    9605
NP_001167597                                                           15    9605
NP_001273164                                                           15    9605
NP_001167601                                                           15    9605
NP_001273166                                                           15    9605
NP_001167596                                                           15    9605
NP_001273163                                                           15    9605
NP_001171765                                                           15    9605
NP_001171764                                                           15    9605
NP_001073327                                                           15    9605
NP_001171766                                                           15    9605
NP_001171763                                                           15    9605
NP_001171762                                                           15    9605
NP_005747                                                              15    9605
NP_001073328                                                           15    9605
NP_001073329                                                           15    9605
NP_001273162                                                           15    9605
NP_703150                                                              15    9605
NP_001167600                                                           15    9605
NP_000608                                                              15    9605
NP_001167599                                                           15    9605
NP_001167598                                                           15    9605
XP_006724519                                                           15    9605
XP_006724518                                                           15    9605
XP_006724517                                                           15    9605
XP_006724516                                                           15    9605
XP_006724515                                                           15    9605
XP_006724514                                                           15    9605
XP_006724513                                                           15    9605
XP_006724512                                                           15    9605
XP_005258156                                                           15    9605
XP_005258155                                                           15    9605
XP_005268973                                                           15    9605
XP_005268971                                                           15    9605
XP_005268970                                                           15    9605
XP_005268969                                                           15    9605
XP_005268968                                                           15    9605
XP_005253374                                                           15    9605
XP_005253372                                                           15    9605
>NP_722576
          Length = 3080

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IPALMVAIT 9
            IPA+MVAIT
Sbjct: 2860 IPAIMVAIT 2868
>XP_005262424
          Length = 2875

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IPALMVAIT 9
            IPA+MVAIT
Sbjct: 2655 IPAIMVAIT 2663
>NP_116176
          Length = 797

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   IPALMVAIT 9
           +PA++VAIT
Sbjct: 577 VPAIVVAIT 585
>XP_005247896
          Length = 502

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   IPALMVAIT 9
           +PA++VAIT
Sbjct: 282 VPAIVVAIT 290
>XP_006713857
          Length = 560

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   IPALMVAIT 9
           +PA++VAIT
Sbjct: 340 VPAIVVAIT 348
>NP_919227
          Length = 419

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  IPALMVAI 8
          IPAL+VA+
Sbjct: 39 IPALLVAV 46
>NP_001693
          Length = 1584

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    IPALMVAIT 9
            +PAL+VAI+
Sbjct: 1060 LPALVVAIS 1068
>XP_005251072
          Length = 1586

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    IPALMVAIT 9
            +PAL+VAI+
Sbjct: 1057 LPALVVAIS 1065
>XP_006710853
          Length = 1478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPALMVAIT 9
           +PAL+VA++
Sbjct: 990 LPALVVAVS 998
>XP_006710852
          Length = 1497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPALMVAIT 9
           +PAL+VA++
Sbjct: 990 LPALVVAVS 998
>XP_006710851
          Length = 1511

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPALMVAIT 9
           +PAL+VA++
Sbjct: 990 LPALVVAVS 998
>XP_006710850
          Length = 1530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPALMVAIT 9
           +PAL+VA++
Sbjct: 990 LPALVVAVS 998
>XP_006710849
          Length = 1530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPALMVAIT 9
           +PAL+VA++
Sbjct: 990 LPALVVAVS 998
>XP_005271124
          Length = 1551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    IPALMVAIT 9
            +PAL+VA++
Sbjct: 1045 LPALVVAVS 1053
>XP_006710848
          Length = 1552

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    IPALMVAIT 9
            +PAL+VA++
Sbjct: 1045 LPALVVAVS 1053
>XP_006710847
          Length = 1566

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    IPALMVAIT 9
            +PAL+VA++
Sbjct: 1045 LPALVVAVS 1053
>XP_006710846
          Length = 1584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    IPALMVAIT 9
            +PAL+VA++
Sbjct: 1045 LPALVVAVS 1053
>NP_001694
          Length = 1585

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    IPALMVAIT 9
            +PAL+VA++
Sbjct: 1045 LPALVVAVS 1053
>NP_056051
          Length = 1469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPALMVAIT 9
           +PAL+VA++
Sbjct: 990 MPALIVAVS 998
>XP_006714219
          Length = 806

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPALMVAIT 9
           +PAL+VA++
Sbjct: 556 MPALIVAVS 564
>XP_006714218
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPALMVAIT 9
           +PAL+VA++
Sbjct: 361 MPALIVAVS 369
>XP_006714217
          Length = 1013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPALMVAIT 9
           +PAL+VA++
Sbjct: 543 MPALIVAVS 551
>XP_006714216
          Length = 1026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IPALMVAIT 9
           +PAL+VA++
Sbjct: 556 MPALIVAVS 564
>NP_008862
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PALMVAIT 9
          PAL+ AIT
Sbjct: 8  PALIFAIT 15
>NP_001243412
          Length = 489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IPALMV 6
           IPALMV
Sbjct: 420 IPALMV 425
>NP_001243411
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IPALMV 6
           IPALMV
Sbjct: 433 IPALMV 438
>NP_001970
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IPALMV 6
           IPALMV
Sbjct: 486 IPALMV 491
>NP_001243413
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IPALMV 6
           IPALMV
Sbjct: 433 IPALMV 438
>NP_001167597
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPALMVAI 8
           IP L+VA+
Sbjct: 421 IPTLLVAV 428
>NP_001273164
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PALMVAIT 9
          PAL+ AIT
Sbjct: 9  PALIFAIT 16
>NP_001167601
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPALMVAI 8
           IP L+VA+
Sbjct: 417 IPTLLVAV 424
>NP_001273166
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PALMVAIT 9
          PAL+ AIT
Sbjct: 47 PALIFAIT 54
>NP_001167596
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPALMVAI 8
           IP L+VA+
Sbjct: 450 IPTLLVAV 457
>NP_001273163
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PALMVAIT 9
          PAL+ AIT
Sbjct: 9  PALIFAIT 16
>NP_001171765
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 597 LPAQMMALT 605
>NP_001171764
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 583 LPAQMMALT 591
>NP_001073327
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 621 LPAQMMALT 629
>NP_001171766
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 591 LPAQMMALT 599
>NP_001171763
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 621 LPAQMMALT 629
>NP_001171762
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 605 LPAQMMALT 613
>NP_005747
          Length = 1014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 618 LPAQMMALT 626
>NP_001073328
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 607 LPAQMMALT 615
>NP_001073329
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 599 LPAQMMALT 607
>NP_001273162
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PALMVAIT 9
          PAL+ AIT
Sbjct: 32 PALIFAIT 39
>NP_703150
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PALMVAIT 9
          PAL+ AIT
Sbjct: 32 PALIFAIT 39
>NP_001167600
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPALMVAI 8
           IP L+VA+
Sbjct: 421 IPTLLVAV 428
>NP_000608
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPALMVAI 8
           IP L+VA+
Sbjct: 421 IPTLLVAV 428
>NP_001167599
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPALMVAI 8
           IP L+VA+
Sbjct: 421 IPTLLVAV 428
>NP_001167598
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPALMVAI 8
           IP L+VA+
Sbjct: 421 IPTLLVAV 428
>XP_006724519
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 621 LPAQMMALT 629
>XP_006724518
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 621 LPAQMMALT 629
>XP_006724517
          Length = 1025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 629 LPAQMMALT 637
>XP_006724516
          Length = 1031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 635 LPAQMMALT 643
>XP_006724515
          Length = 1039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 643 LPAQMMALT 651
>XP_006724514
          Length = 1041

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 645 LPAQMMALT 653
>XP_006724513
          Length = 1052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 656 LPAQMMALT 664
>XP_006724512
          Length = 1055

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           +PA M+A+T
Sbjct: 659 LPAQMMALT 667
>XP_005258156
          Length = 1905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           IPA+ +A+T
Sbjct: 183 IPAVTLAVT 191
>XP_005258155
          Length = 1970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IPALMVAIT 9
           IPA+ +A+T
Sbjct: 183 IPAVTLAVT 191
>XP_005268973
          Length = 489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPALMVAI 8
           IP L+VA+
Sbjct: 342 IPTLLVAV 349
>XP_005268971
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPALMVAI 8
           IP L+VA+
Sbjct: 384 IPTLLVAV 391
>XP_005268970
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPALMVAI 8
           IP L+VA+
Sbjct: 384 IPTLLVAV 391
>XP_005268969
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPALMVAI 8
           IP L+VA+
Sbjct: 417 IPTLLVAV 424
>XP_005268968
          Length = 597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IPALMVAI 8
           IP L+VA+
Sbjct: 450 IPTLLVAV 457
>XP_005253374
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PALMVAIT 9
          PAL+ AIT
Sbjct: 9  PALIFAIT 16
>XP_005253372
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  PALMVAIT 9
          PAL+ AIT
Sbjct: 9  PALIFAIT 16
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.336    0.141    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 325,431
Number of extensions: 422
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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