Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1135
NP_001185763                                                           18    1135
NP_055459                                                              18    1135
XP_006726410                                                           18    1135
XP_006711719                                                           18    1135
XP_006711718                                                           18    1135
XP_006711717                                                           18    1135
XP_006711716                                                           18    1135
XP_006711715                                                           18    1135
XP_006711714                                                           18    1135
XP_006711713                                                           18    1135
XP_006711711                                                           18    1135
XP_006711710                                                           18    1135
XP_006711709                                                           18    1135
XP_005277503                                                           18    1135
XP_005273038                                                           18    1135
XP_006711708                                                           18    1135
XP_005277500                                                           18    1135
XP_005277499                                                           18    1135
XP_006711706                                                           18    1135
XP_006711705                                                           18    1135
XP_006711164                                                           18    1135
XP_003846805                                                           18    1135
NP_005145                                                              17    2528
NP_001122082                                                           17    2528
NP_001269978                                                           17    2528
XP_006720825                                                           17    2528
XP_006720824                                                           17    2528
NP_000493                                                              16    5631
NP_001265542                                                           16    5631
XP_006722191                                                           16    5631
XP_005268511                                                           16    5631
XP_005268509                                                           16    5631
NP_006436                                                              16    7355
NP_001243199                                                           16    7355
NP_015556                                                              16    7355
NP_003354                                                              16    7355
NP_003794                                                              16    7355
NP_062830                                                              16    7355
NP_955475                                                              16    7355
NP_001243198                                                           16    7355
NP_009054                                                              15    9605
NP_996816                                                              15    9605
NP_001017916                                                           15    9605
NP_001017917                                                           15    9605
NP_001906                                                              15    9605
NP_060887                                                              15    9605
NP_001161221                                                           15    9605
NP_004721                                                              15    9605
NP_001243231                                                           15    9605
NP_001269114                                                           15    9605
NP_065744                                                              15    9605
NP_775922                                                              15    9605
XP_005257147                                                           15    9605
XP_005257149                                                           15    9605
XP_006721790                                                           15    9605
XP_005257148                                                           15    9605
XP_005271978                                                           15    9605
XP_005271977                                                           15    9605
XP_005245387                                                           15    9605
XP_005245386                                                           15    9605
XP_006711512                                                           15    9605
NP_005459                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2037 INRANGLGL 2045
>NP_001185763
          Length = 2362

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2143 INRANGLGL 2151
>NP_055459
          Length = 2346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2143 INRANGLGL 2151
>XP_006726410
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 1884 INRANGLGL 1892
>XP_006711719
          Length = 2302

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2099 INRANGLGL 2107
>XP_006711718
          Length = 1436

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 1150 INRANGLGL 1158
>XP_006711717
          Length = 2385

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2099 INRANGLGL 2107
>XP_006711716
          Length = 2411

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2208 INRANGLGL 2216
>XP_006711715
          Length = 2428

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2142 INRANGLGL 2150
>XP_006711714
          Length = 2429

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2143 INRANGLGL 2151
>XP_006711713
          Length = 2432

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2146 INRANGLGL 2154
>XP_006711711
          Length = 2482

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2196 INRANGLGL 2204
>XP_006711710
          Length = 2494

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2208 INRANGLGL 2216
>XP_006711709
          Length = 2495

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2209 INRANGLGL 2217
>XP_005277503
          Length = 2498

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2306 INRANGLGL 2314
>XP_005273038
          Length = 2509

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2306 INRANGLGL 2314
>XP_006711708
          Length = 2512

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2226 INRANGLGL 2234
>XP_005277500
          Length = 2525

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2306 INRANGLGL 2314
>XP_005277499
          Length = 2561

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2306 INRANGLGL 2314
>XP_006711706
          Length = 2591

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2305 INRANGLGL 2313
>XP_006711705
          Length = 2592

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 2306 INRANGLGL 2314
>XP_006711164
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            INRAN LGL
Sbjct: 1884 INRANGLGL 1892
>XP_003846805
          Length = 306

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   INRANVLGL 9
           INRAN LGL
Sbjct: 139 INRANGLGL 147
>NP_005145
          Length = 1118

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   INRANVLG 8
           INR+N+LG
Sbjct: 814 INRSNLLG 821
>NP_001122082
          Length = 1118

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   INRANVLG 8
           INR+N+LG
Sbjct: 814 INRSNLLG 821
>NP_001269978
          Length = 1012

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   INRANVLG 8
           INR+N+LG
Sbjct: 708 INRSNLLG 715
>XP_006720825
          Length = 1089

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   INRANVLG 8
           INR+N+LG
Sbjct: 785 INRSNLLG 792
>XP_006720824
          Length = 1118

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   INRANVLG 8
           INR+N+LG
Sbjct: 814 INRSNLLG 821
>NP_000493
          Length = 715

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NRANVLGL 9
           NR N LGL
Sbjct: 327 NRTNYLGL 334
>NP_001265542
          Length = 1076

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NRANVLGL 9
          NR +VLGL
Sbjct: 10 NRGSVLGL 17
>XP_006722191
          Length = 715

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NRANVLGL 9
           NR N LGL
Sbjct: 327 NRTNYLGL 334
>XP_005268511
          Length = 1158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NRANVLGL 9
          NR +VLGL
Sbjct: 38 NRGSVLGL 45
>XP_005268509
          Length = 1281

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NRANVLGL 9
          NR +VLGL
Sbjct: 38 NRGSVLGL 45
>NP_006436
          Length = 2335

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    INRANV 6
            INRANV
Sbjct: 1542 INRANV 1547
>NP_001243199
          Length = 597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RANVLGL 9
           +AN+LGL
Sbjct: 582 KANILGL 588
>NP_015556
          Length = 665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RANVLGL 9
           +AN+LGL
Sbjct: 650 KANILGL 656
>NP_003354
          Length = 963

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   INRANVLGL 9
           INR N LG+
Sbjct: 339 INRDNPLGM 347
>NP_003794
          Length = 1685

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    NRANVLG 8
            NRA VLG
Sbjct: 1570 NRARVLG 1576
>NP_062830
          Length = 1589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    NRANVLG 8
            NRA VLG
Sbjct: 1474 NRARVLG 1480
>NP_955475
          Length = 916

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   INRANVLGL 9
           INR N LG+
Sbjct: 292 INRDNPLGM 300
>NP_001243198
          Length = 597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RANVLGL 9
           +AN+LGL
Sbjct: 582 KANILGL 588
>NP_009054
          Length = 1546

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RANVLGL 9
           +ANV+GL
Sbjct: 718 KANVIGL 724
>NP_996816
          Length = 5202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RANVLGL 9
           +ANV+GL
Sbjct: 718 KANVIGL 724
>NP_001017916
          Length = 251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ANVLGL 9
           ANVLGL
Sbjct: 201 ANVLGL 206
>NP_001017917
          Length = 251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ANVLGL 9
           ANVLGL
Sbjct: 201 ANVLGL 206
>NP_001906
          Length = 251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ANVLGL 9
           ANVLGL
Sbjct: 201 ANVLGL 206
>NP_060887
          Length = 1610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ANVLGL 9
           ANVLGL
Sbjct: 562 ANVLGL 567
>NP_001161221
          Length = 1457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ANVLGL 9
           ANVLGL
Sbjct: 409 ANVLGL 414
>NP_004721
          Length = 437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  INRANVLG 8
          +NR +VLG
Sbjct: 66 VNRLSVLG 73
>NP_001243231
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  INRANVLG 8
          +NR +VLG
Sbjct: 33 VNRLSVLG 40
>NP_001269114
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  INRANVLG 8
          +NR +VLG
Sbjct: 52 VNRLSVLG 59
>NP_065744
          Length = 2113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    INRANVLGL 9
            IN+AN++ L
Sbjct: 1004 INQANIVDL 1012
>NP_775922
          Length = 6996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    INRANVLGL 9
            IN+ NVL L
Sbjct: 1883 INQLNVLSL 1891
>XP_005257147
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ANVLGL 9
           ANVLGL
Sbjct: 268 ANVLGL 273
>XP_005257149
          Length = 222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ANVLGL 9
           ANVLGL
Sbjct: 172 ANVLGL 177
>XP_006721790
          Length = 249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ANVLGL 9
           ANVLGL
Sbjct: 199 ANVLGL 204
>XP_005257148
          Length = 251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ANVLGL 9
           ANVLGL
Sbjct: 201 ANVLGL 206
>XP_005271978
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  INRANVLG 8
          +NR +VLG
Sbjct: 33 VNRLSVLG 40
>XP_005271977
          Length = 404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  INRANVLG 8
          +NR +VLG
Sbjct: 33 VNRLSVLG 40
>XP_005245387
          Length = 1203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ANVLGL 9
           ANVLGL
Sbjct: 562 ANVLGL 567
>XP_005245386
          Length = 1518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ANVLGL 9
           ANVLGL
Sbjct: 470 ANVLGL 475
>XP_006711512
          Length = 1547

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ANVLGL 9
           ANVLGL
Sbjct: 562 ANVLGL 567
>NP_005459
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NRANVLGL 9
           N +NVLG+
Sbjct: 345 NSSNVLGI 352
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.146    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 383,847
Number of extensions: 544
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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