Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           20     299
NP_000242                                                              20     299
XP_005264389                                                           20     299
NP_997320                                                              17    4312
NP_001361                                                              17    4312
XP_005253612                                                           17    4312
XP_006712019                                                           17    4312
NP_060918                                                              17    4312
NP_002572                                                              16    5631
NP_002026                                                              16    5631
NP_001231191                                                           16    5631
XP_005266734                                                           16    5631
XP_006722496                                                           16    5631
XP_005250324                                                           16    5631
XP_005250323                                                           16    5631
NP_036389                                                              16    5631
NP_758859                                                              16    7355
NP_071900                                                              16    7355
NP_001182121                                                           16    7355
NP_001264156                                                           16    7355
NP_003658                                                              16    7355
NP_001264155                                                           16    7355
NP_689560                                                              16    7355
NP_776152                                                              16    7355
NP_001035847                                                           16    7355
NP_005125                                                              16    7355
NP_079520                                                              16    7355
NP_878915                                                              16    7355
XP_005269261                                                           16    7355
XP_005269575                                                           16    7355
XP_006714967                                                           16    7355
XP_006714966                                                           16    7355
XP_005266018                                                           16    7355
XP_005266017                                                           16    7355
XP_006714965                                                           16    7355
XP_006714964                                                           16    7355
XP_005266016                                                           16    7355
XP_006712845                                                           16    7355
XP_005264086                                                           16    7355
XP_005264084                                                           16    7355
XP_005264083                                                           16    7355
XP_006712844                                                           16    7355
XP_005264082                                                           16    7355
XP_005264081                                                           16    7355
XP_005264080                                                           16    7355
XP_006712843                                                           16    7355
XP_005264079                                                           16    7355
NP_001007028                                                           15    9605
NP_006436                                                              15    9605
NP_076984                                                              15    9605
NP_001240317                                                           15    9605
NP_001240316                                                           15    9605
NP_001138498                                                           15    9605
NP_006605                                                              15    9605
NP_002709                                                              15    9605
NP_056083                                                              15    9605
NP_055506                                                              15    9605
NP_542376                                                              15    9605
NP_004361                                                              15    9605
NP_113628                                                              15    9605
NP_064501                                                              15    9605
NP_001121899                                                           15    9605
NP_001121900                                                           15    9605
XP_006719488                                                           15    9605
XP_006719487                                                           15    9605
XP_005274304                                                           15    9605
XP_006715397                                                           15    9605
XP_006713749                                                           15    9605
XP_005247302                                                           15    9605
XP_006713004                                                           15    9605
XP_006713003                                                           15    9605
XP_006713002                                                           15    9605
XP_006713001                                                           15    9605
NP_055020                                                              15    9605
>NP_001245210
          Length = 868

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   INQLPNVIK 9
           INQLPNVI+
Sbjct: 345 INQLPNVIQ 353
>NP_000242
          Length = 934

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   INQLPNVIK 9
           INQLPNVI+
Sbjct: 411 INQLPNVIQ 419
>XP_005264389
          Length = 921

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   INQLPNVIK 9
           INQLPNVI+
Sbjct: 411 INQLPNVIQ 419
>NP_997320
          Length = 4471

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    INQLPNVIK 9
            +NQ+PN ++
Sbjct: 2265 VNQIPNKVE 2273
>NP_001361
          Length = 4158

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    INQLPNVIK 9
            +N+LPN ++
Sbjct: 1145 VNRLPNALR 1153
>XP_005253612
          Length = 4589

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    INQLPNVIK 9
            +NQ+PN ++
Sbjct: 2383 VNQIPNKVE 2391
>XP_006712019
          Length = 4158

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    INQLPNVIK 9
            +N+LPN ++
Sbjct: 1145 VNRLPNALR 1153
>NP_060918
          Length = 1230

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   NQLPNVIK 9
           +Q+PN++K
Sbjct: 430 SQVPNIVK 437
>NP_002572
          Length = 1627

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   INQLPNVIK 9
           +N+L N++K
Sbjct: 498 VNELKNILK 506
>NP_002026
          Length = 332

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NQLPNVIK 9
           NQ+ NVIK
Sbjct: 99  NQVENVIK 106
>NP_001231191
          Length = 524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  NQLPNVIK 9
          NQ+PN ++
Sbjct: 18 NQMPNAVQ 25
>XP_005266734
          Length = 298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NQLPNVIK 9
           NQ+ NVIK
Sbjct: 99  NQVENVIK 106
>XP_006722496
          Length = 303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  NQLPNVIK 9
          NQ+ NVIK
Sbjct: 70 NQVENVIK 77
>XP_005250324
          Length = 514

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  NQLPNVIK 9
          NQ+PN ++
Sbjct: 8  NQMPNAVQ 15
>XP_005250323
          Length = 514

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  NQLPNVIK 9
          NQ+PN ++
Sbjct: 8  NQMPNAVQ 15
>NP_036389
          Length = 514

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  NQLPNVIK 9
          NQ+PN ++
Sbjct: 8  NQMPNAVQ 15
>NP_758859
          Length = 2427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   INQLPNV 7
           +NQLP+V
Sbjct: 787 LNQLPSV 793
>NP_071900
          Length = 2696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    INQLPNV 7
            +NQLP+V
Sbjct: 1056 LNQLPSV 1062
>NP_001182121
          Length = 784

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NQLPNVIK 9
           N LP VIK
Sbjct: 431 NALPGVIK 438
>NP_001264156
          Length = 835

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NQLPNV 7
           NQLPN+
Sbjct: 277 NQLPNL 282
>NP_003658
          Length = 907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NQLPNV 7
           NQLPN+
Sbjct: 349 NQLPNL 354
>NP_001264155
          Length = 883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NQLPNV 7
           NQLPN+
Sbjct: 325 NQLPNL 330
>NP_689560
          Length = 973

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NQLPNVIK 9
           N LP VIK
Sbjct: 527 NALPGVIK 534
>NP_776152
          Length = 1154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   INQLPNVIK 9
           +NQL  +IK
Sbjct: 272 VNQLKKIIK 280
>NP_001035847
          Length = 950

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   INQLPN 6
           IN+LPN
Sbjct: 560 INELPN 565
>NP_005125
          Length = 933

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   INQLPN 6
           IN+LPN
Sbjct: 543 INELPN 548
>NP_079520
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   INQLPNVIK 9
           +N+L N++K
Sbjct: 396 VNKLKNILK 404
>NP_878915
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   INQLPNVIK 9
           +N+L N++K
Sbjct: 396 VNKLKNILK 404
>XP_005269261
          Length = 833

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NQLPNV 7
           NQLPN+
Sbjct: 275 NQLPNL 280
>XP_005269575
          Length = 1113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   INQLPNVIK 9
           +NQL  +IK
Sbjct: 272 VNQLKKIIK 280
>XP_006714967
          Length = 1327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    INQLPNV 7
            +NQLP+V
Sbjct: 1056 LNQLPSV 1062
>XP_006714966
          Length = 1499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    INQLPNV 7
            +NQLP+V
Sbjct: 1056 LNQLPSV 1062
>XP_005266018
          Length = 2427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   INQLPNV 7
           +NQLP+V
Sbjct: 787 LNQLPSV 793
>XP_005266017
          Length = 2427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   INQLPNV 7
           +NQLP+V
Sbjct: 787 LNQLPSV 793
>XP_006714965
          Length = 2427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   INQLPNV 7
           +NQLP+V
Sbjct: 787 LNQLPSV 793
>XP_006714964
          Length = 2696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    INQLPNV 7
            +NQLP+V
Sbjct: 1056 LNQLPSV 1062
>XP_005266016
          Length = 2696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    INQLPNV 7
            +NQLP+V
Sbjct: 1056 LNQLPSV 1062
>XP_006712845
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   INQLPNVIK 9
           +N+L N++K
Sbjct: 396 VNKLKNILK 404
>XP_005264086
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   INQLPNVIK 9
           +N+L N++K
Sbjct: 396 VNKLKNILK 404
>XP_005264084
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   INQLPNVIK 9
           +N+L N++K
Sbjct: 396 VNKLKNILK 404
>XP_005264083
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   INQLPNVIK 9
           +N+L N++K
Sbjct: 396 VNKLKNILK 404
>XP_006712844
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   INQLPNVIK 9
           +N+L N++K
Sbjct: 396 VNKLKNILK 404
>XP_005264082
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   INQLPNVIK 9
           +N+L N++K
Sbjct: 396 VNKLKNILK 404
>XP_005264081
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   INQLPNVIK 9
           +N+L N++K
Sbjct: 396 VNKLKNILK 404
>XP_005264080
          Length = 698

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   INQLPNVIK 9
           +N+L N++K
Sbjct: 396 VNKLKNILK 404
>XP_006712843
          Length = 891

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   INQLPNVIK 9
           +N+L N++K
Sbjct: 596 VNKLKNILK 604
>XP_005264079
          Length = 893

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   INQLPNVIK 9
           +N+L N++K
Sbjct: 591 VNKLKNILK 599
>NP_001007028
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   INQLPNV 7
           +NQLP V
Sbjct: 259 LNQLPQV 265
>NP_006436
          Length = 2335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    INQLPN 6
            +NQ+PN
Sbjct: 1526 LNQIPN 1531
>NP_076984
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   INQLPNV 7
           +NQLP V
Sbjct: 259 LNQLPQV 265
>NP_001240317
          Length = 1171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  INQLPNVIK 9
          + Q+P +IK
Sbjct: 31 VQQVPTIIK 39
>NP_001240316
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  INQLPNVIK 9
          + Q+P +IK
Sbjct: 31 VQQVPTIIK 39
>NP_001138498
          Length = 2299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    NQLPNVIK 9
            NQ  NV+K
Sbjct: 1325 NQFSNVVK 1332
>NP_006605
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  INQLPNVIK 9
          + Q+P +IK
Sbjct: 31 VQQVPTIIK 39
>NP_002709
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   INQLPNVIK 9
           I Q P VIK
Sbjct: 657 IQQTPEVIK 665
>NP_056083
          Length = 2243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    INQLPNVIK 9
            I ++P++IK
Sbjct: 1494 ITEMPSIIK 1502
>NP_055506
          Length = 1485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    NQLPNVIK 9
            +QLP VIK
Sbjct: 1098 HQLPPVIK 1105
>NP_542376
          Length = 1899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    INQLPN 6
            +NQ+PN
Sbjct: 1763 LNQIPN 1768
>NP_004361
          Length = 3063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    INQLPN 6
            +NQ+PN
Sbjct: 2927 LNQIPN 2932
>NP_113628
          Length = 232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LPNVIK 9
          LPNV+K
Sbjct: 34 LPNVLK 39
>NP_064501
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   INQLPNVIK 9
           IN+L  VIK
Sbjct: 197 INELTQVIK 205
>NP_001121899
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   INQLPNVIK 9
           IN+L  VIK
Sbjct: 196 INELTQVIK 204
>NP_001121900
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   INQLPNVIK 9
           IN+L  VIK
Sbjct: 196 INELTQVIK 204
>XP_006719488
          Length = 328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  INQLPNVIK 9
          I+ LP V+K
Sbjct: 4  IDNLPRVVK 12
>XP_006719487
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  INQLPNVIK 9
          I+ LP V+K
Sbjct: 4  IDNLPRVVK 12
>XP_005274304
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   INQLPNV 7
           +NQLP V
Sbjct: 250 LNQLPQV 256
>XP_006715397
          Length = 2972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1    INQLPN 6
            +NQ+PN
Sbjct: 2836 LNQIPN 2841
>XP_006713749
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   INQLPNVIK 9
           I Q P VIK
Sbjct: 657 IQQTPEVIK 665
>XP_005247302
          Length = 2248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    INQLPNVIK 9
            I ++P++IK
Sbjct: 1499 ITEMPSIIK 1507
>XP_006713004
          Length = 1171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  INQLPNVIK 9
          + Q+P +IK
Sbjct: 31 VQQVPTIIK 39
>XP_006713003
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  INQLPNVIK 9
          + Q+P +IK
Sbjct: 31 VQQVPTIIK 39
>XP_006713002
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  INQLPNVIK 9
          + Q+P +IK
Sbjct: 31 VQQVPTIIK 39
>XP_006713001
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  INQLPNVIK 9
          + Q+P +IK
Sbjct: 31 VQQVPTIIK 39
>NP_055020
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   QLPNVI 8
           QLPNV+
Sbjct: 214 QLPNVL 219
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.141    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 725,606
Number of extensions: 963
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package