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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_689417                                                              18    1135
XP_006720248                                                           18    1135
XP_005267848                                                           18    1135
NP_060413                                                              18    1135
NP_839955                                                              17    4312
NP_001020095                                                           17    4312
XP_005265807                                                           17    4312
XP_006714105                                                           17    4312
XP_005265805                                                           17    4312
XP_005265804                                                           17    4312
NP_060731                                                              17    4312
NP_001193723                                                           16    7355
NP_112739                                                              16    7355
NP_002883                                                              16    7355
NP_075377                                                              16    7355
NP_075376                                                              16    7355
NP_057458                                                              16    7355
XP_005268022                                                           16    7355
XP_005268021                                                           16    7355
XP_005273217                                                           16    7355
XP_006711844                                                           16    7355
XP_006711507                                                           16    7355
NP_055851                                                              15    9605
NP_001964                                                              15    9605
XP_005245008                                                           15    9605
XP_005245007                                                           15    9605
NP_068567                                                              15    9605

>NP_689417
          Length = 711

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   IMIKLFRLI 9
           IM+K+FRL+
Sbjct: 582 IMVKIFRLL 590



>XP_006720248
          Length = 711

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   IMIKLFRLI 9
           IM+K+FRL+
Sbjct: 582 IMVKIFRLL 590



>XP_005267848
          Length = 711

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   IMIKLFRLI 9
           IM+K+FRL+
Sbjct: 582 IMVKIFRLL 590



>NP_060413
          Length = 711

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   IMIKLFRLI 9
           IM+K+FRL+
Sbjct: 582 IMVKIFRLL 590



>NP_839955
          Length = 879

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IMIKLFRLI 9
           +MIK+FR I
Sbjct: 567 MMIKIFRCI 575



>NP_001020095
          Length = 894

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IMIKLFRLI 9
           +MIK+FR I
Sbjct: 582 MMIKIFRCI 590



>XP_005265807
          Length = 879

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IMIKLFRLI 9
           +MIK+FR I
Sbjct: 567 MMIKIFRCI 575



>XP_006714105
          Length = 897

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IMIKLFRLI 9
           +MIK+FR I
Sbjct: 585 MMIKIFRCI 593



>XP_005265805
          Length = 912

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IMIKLFRLI 9
           +MIK+FR I
Sbjct: 600 MMIKIFRCI 608



>XP_005265804
          Length = 912

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IMIKLFRLI 9
           +MIK+FR I
Sbjct: 600 MMIKIFRCI 608



>NP_060731
          Length = 894

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IMIKLFRLI 9
           +MIK+FR I
Sbjct: 582 MMIKIFRCI 590



>NP_001193723
          Length = 1312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MIKLFRLI 9
           + KLFRL+
Sbjct: 340 LFKLFRLV 347



>NP_112739
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MIKLFRLI 9
           + KLFRL+
Sbjct: 340 LFKLFRLV 347



>NP_002883
          Length = 1257

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MIKLFRLI 9
           + KLFRL+
Sbjct: 343 LFKLFRLV 350



>NP_075377
          Length = 1188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MIKLFRLI 9
           + KLFRL+
Sbjct: 343 LFKLFRLV 350



>NP_075376
          Length = 1203

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MIKLFRLI 9
           + KLFRL+
Sbjct: 343 LFKLFRLV 350



>NP_057458
          Length = 1312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MIKLFRLI 9
           + KLFRL+
Sbjct: 340 LFKLFRLV 347



>XP_005268022
          Length = 1208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MIKLFRLI 9
           + KLFRL+
Sbjct: 343 LFKLFRLV 350



>XP_005268021
          Length = 1277

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MIKLFRLI 9
           + KLFRL+
Sbjct: 343 LFKLFRLV 350



>XP_005273217
          Length = 1141

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MIKLFRLI 9
           + KLFRL+
Sbjct: 340 LFKLFRLV 347



>XP_006711844
          Length = 1276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MIKLFRLI 9
           + KLFRL+
Sbjct: 340 LFKLFRLV 347



>XP_006711507
          Length = 354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   MIKLFRLI 9
           M+K+F+L+
Sbjct: 345 MVKIFKLL 352



>NP_055851
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   IKLFRLI 9
           IKLF+LI
Sbjct: 340 IKLFQLI 346



>NP_001964
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IKLFRLI 9
           +KLF+LI
Sbjct: 160 VKLFKLI 166



>XP_005245008
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IKLFRLI 9
           +KLF+LI
Sbjct: 160 VKLFKLI 166



>XP_005245007
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IKLFRLI 9
           +KLF+LI
Sbjct: 160 VKLFKLI 166



>NP_068567
          Length = 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IKLFRLI 9
           +KLF+LI
Sbjct: 160 VKLFKLI 166



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.367    0.180    0.470 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 290,485
Number of extensions: 308
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (17.3 bits)
S2: 28 (15.4 bits)