Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              20     509
NP_001120972                                                           20     509
XP_006716052                                                           20     509
XP_006716051                                                           20     509
NP_891550                                                              18    1935
XP_005265386                                                           18    1935
NP_619639                                                              17    4312
NP_037472                                                              17    4312
XP_005270452                                                           17    4312
NP_006836                                                              17    4312
NP_071935                                                              16    5631
NP_001128206                                                           16    5631
NP_001127945                                                           16    7355
NP_002110                                                              16    7355
NP_001265113                                                           16    7355
NP_055430                                                              16    7355
NP_005119                                                              16    7355
XP_006726149                                                           16    7355
XP_005275597                                                           16    7355
XP_006726059                                                           16    7355
XP_005275440                                                           16    7355
XP_006725969                                                           16    7355
XP_005275300                                                           16    7355
XP_006725878                                                           16    7355
XP_005275163                                                           16    7355
XP_006725760                                                           16    7355
XP_005275008                                                           16    7355
XP_006725546                                                           16    7355
XP_005272861                                                           16    7355
XP_006724131                                                           16    7355
XP_005255922                                                           16    7355
XP_006721236                                                           16    7355
XP_006721235                                                           16    7355
XP_005255921                                                           16    7355
XP_005255920                                                           16    7355
XP_005255919                                                           16    7355
XP_005255918                                                           16    7355
XP_005255917                                                           16    7355
XP_005255916                                                           16    7355
XP_006715139                                                           16    7355
XP_005249104                                                           16    7355
NP_001028728                                                           15    9605
NP_002697                                                              15    9605
NP_001028729                                                           15    9605
NP_808907                                                              15    9605
NP_005145                                                              15    9605
NP_001122082                                                           15    9605
NP_001269978                                                           15    9605
NP_001153059                                                           15    9605
NP_001153060                                                           15    9605
NP_598000                                                              15    9605
NP_003927                                                              15    9605
NP_808821                                                              15    9605
NP_808820                                                              15    9605
NP_066277                                                              15    9605
NP_060466                                                              15    9605
NP_001137546                                                           15    9605
NP_919278                                                              15    9605
XP_006720825                                                           15    9605
XP_006720824                                                           15    9605
XP_006720243                                                           15    9605
XP_006720242                                                           15    9605
XP_005267838                                                           15    9605
XP_005267837                                                           15    9605
XP_005267836                                                           15    9605
XP_005267834                                                           15    9605
XP_005267835                                                           15    9605
XP_005248716                                                           15    9605
XP_006712459                                                           15    9605
NP_443085                                                              15    9605
NP_066283                                                              15    9605
>NP_000236
          Length = 1390

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVQRSNGE 9
          LVQRSNGE
Sbjct: 18 LVQRSNGE 25
>NP_001120972
          Length = 1408

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVQRSNGE 9
          LVQRSNGE
Sbjct: 18 LVQRSNGE 25
>XP_006716052
          Length = 1409

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVQRSNGE 9
          LVQRSNGE
Sbjct: 37 LVQRSNGE 44
>XP_006716051
          Length = 1427

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVQRSNGE 9
          LVQRSNGE
Sbjct: 37 LVQRSNGE 44
>NP_891550
          Length = 1935

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ILVQRSNGE 9
            ++ QRSNGE
Sbjct: 1407 VVCQRSNGE 1415
>XP_005265386
          Length = 1907

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ILVQRSNGE 9
            ++ QRSNGE
Sbjct: 1379 VVCQRSNGE 1387
>NP_619639
          Length = 4074

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ILVQRSNGE 9
            ILVQ S+GE
Sbjct: 3745 ILVQPSDGE 3753
>NP_037472
          Length = 818

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VQRSNGE 9
           VQR NGE
Sbjct: 618 VQRQNGE 624
>XP_005270452
          Length = 684

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ILVQRSNG 8
          I +QRSNG
Sbjct: 17 IKIQRSNG 24
>NP_006836
          Length = 725

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ILVQRSNG 8
          I +QRSNG
Sbjct: 17 IKIQRSNG 24
>NP_071935
          Length = 419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILVQRSNGE 9
          +LVQ SNG+
Sbjct: 24 VLVQFSNGK 32
>NP_001128206
          Length = 598

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILVQRSNGE 9
           ILV+ S+GE
Sbjct: 135 ILVEESSGE 143
>NP_001127945
          Length = 1113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILVQRSNGE 9
           +L+QR+N E
Sbjct: 382 LLIQRTNEE 390
>NP_002110
          Length = 250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILVQRSN 7
           ILV+RSN
Sbjct: 98  ILVERSN 104
>NP_001265113
          Length = 1144

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILVQRSNGE 9
           +L+QR+N E
Sbjct: 413 LLIQRTNEE 421
>NP_055430
          Length = 1217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILVQRSNGE 9
           +L+QR+N E
Sbjct: 486 LLIQRTNEE 494
>NP_005119
          Length = 2298

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILVQRSNGE 9
           +LVQR+N E
Sbjct: 240 VLVQRNNLE 248
>XP_006726149
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ILVQRSN 7
          ILV+RSN
Sbjct: 68 ILVERSN 74
>XP_005275597
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILVQRSN 7
           ILV+RSN
Sbjct: 98  ILVERSN 104
>XP_006726059
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ILVQRSN 7
          ILV+RSN
Sbjct: 68 ILVERSN 74
>XP_005275440
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILVQRSN 7
           ILV+RSN
Sbjct: 98  ILVERSN 104
>XP_006725969
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ILVQRSN 7
          ILV+RSN
Sbjct: 68 ILVERSN 74
>XP_005275300
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILVQRSN 7
           ILV+RSN
Sbjct: 98  ILVERSN 104
>XP_006725878
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ILVQRSN 7
          ILV+RSN
Sbjct: 68 ILVERSN 74
>XP_005275163
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILVQRSN 7
           ILV+RSN
Sbjct: 98  ILVERSN 104
>XP_006725760
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ILVQRSN 7
          ILV+RSN
Sbjct: 68 ILVERSN 74
>XP_005275008
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILVQRSN 7
           ILV+RSN
Sbjct: 98  ILVERSN 104
>XP_006725546
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ILVQRSN 7
          ILV+RSN
Sbjct: 68 ILVERSN 74
>XP_005272861
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILVQRSN 7
           ILV+RSN
Sbjct: 98  ILVERSN 104
>XP_006724131
          Length = 2298

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILVQRSNGE 9
           +LVQR+N E
Sbjct: 240 VLVQRNNLE 248
>XP_005255922
          Length = 1154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILVQRSNGE 9
           +L+QR+N E
Sbjct: 423 LLIQRTNEE 431
>XP_006721236
          Length = 1214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILVQRSNGE 9
           +L+QR+N E
Sbjct: 483 LLIQRTNEE 491
>XP_006721235
          Length = 1214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILVQRSNGE 9
           +L+QR+N E
Sbjct: 483 LLIQRTNEE 491
>XP_005255921
          Length = 1227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILVQRSNGE 9
           +L+QR+N E
Sbjct: 496 LLIQRTNEE 504
>XP_005255920
          Length = 1229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILVQRSNGE 9
           +L+QR+N E
Sbjct: 498 LLIQRTNEE 506
>XP_005255919
          Length = 1860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ILVQRSNGE 9
            +L+QR+N E
Sbjct: 1291 LLIQRTNEE 1299
>XP_005255918
          Length = 1949

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ILVQRSNGE 9
            +L+QR+N E
Sbjct: 1218 LLIQRTNEE 1226
>XP_005255917
          Length = 1984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ILVQRSNGE 9
            +L+QR+N E
Sbjct: 1291 LLIQRTNEE 1299
>XP_005255916
          Length = 2022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ILVQRSNGE 9
            +L+QR+N E
Sbjct: 1291 LLIQRTNEE 1299
>XP_006715139
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ILVQRSN 7
          ILV+RSN
Sbjct: 68 ILVERSN 74
>XP_005249104
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILVQRSN 7
           ILV+RSN
Sbjct: 98  ILVERSN 104
>NP_001028728
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 187 VMIQRVNG 194
>NP_002697
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 187 VMIQRVNG 194
>NP_001028729
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 187 VMIQRVNG 194
>NP_808907
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 187 VMIQRVNG 194
>NP_005145
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QRSNGE 9
           Q+SNGE
Sbjct: 165 QKSNGE 170
>NP_001122082
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QRSNGE 9
           Q+SNGE
Sbjct: 165 QKSNGE 170
>NP_001269978
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  QRSNGE 9
          Q+SNGE
Sbjct: 88 QKSNGE 93
>NP_001153059
          Length = 1428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QRSNGE 9
            Q+SNGE
Sbjct: 1021 QKSNGE 1026
>NP_001153060
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QRSNGE 9
           Q+SNGE
Sbjct: 944 QKSNGE 949
>NP_598000
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QRSNGE 9
            Q+SNGE
Sbjct: 1021 QKSNGE 1026
>NP_003927
          Length = 367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILVQRSNGE 9
           ++VQ S GE
Sbjct: 177 VIVQASTGE 185
>NP_808821
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 255 VMIQRVNG 262
>NP_808820
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 182 VMIQRVNG 189
>NP_066277
          Length = 366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LVQRSNGE 9
          L+QRS+G+
Sbjct: 64 LLQRSHGD 71
>NP_060466
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILVQRSNGE 9
           I VQR+N E
Sbjct: 541 ISVQRTNAE 549
>NP_001137546
          Length = 550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILVQRSNGE 9
           I VQR+N E
Sbjct: 530 ISVQRTNAE 538
>NP_919278
          Length = 1925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ILVQRSNGE 9
            ILV+ S GE
Sbjct: 1871 ILVEASRGE 1879
>XP_006720825
          Length = 1089

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QRSNGE 9
           Q+SNGE
Sbjct: 165 QKSNGE 170
>XP_006720824
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QRSNGE 9
           Q+SNGE
Sbjct: 165 QKSNGE 170
>XP_006720243
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 182 VMIQRVNG 189
>XP_006720242
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 182 VMIQRVNG 189
>XP_005267838
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 182 VMIQRVNG 189
>XP_005267837
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 182 VMIQRVNG 189
>XP_005267836
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 182 VMIQRVNG 189
>XP_005267834
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 182 VMIQRVNG 189
>XP_005267835
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 182 VMIQRVNG 189
>XP_005248716
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QRSNGE 9
            Q+SNGE
Sbjct: 1021 QKSNGE 1026
>XP_006712459
          Length = 1914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ILVQRSNGE 9
            ILV+ S GE
Sbjct: 1860 ILVEASRGE 1868
>NP_443085
          Length = 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           ILVQ +NG
Sbjct: 451 ILVQGANG 458
>NP_066283
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   ILVQRSNG 8
           +++QR NG
Sbjct: 182 VMIQRVNG 189
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.133    0.336 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 550,137
Number of extensions: 748
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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