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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_689991                                                              17    2528
XP_005262955                                                           17    2528
XP_005262954                                                           17    2528
XP_005262953                                                           17    2528
XP_005262950                                                           17    2528
NP_001005471                                                           17    3301
NP_001017415                                                           16    5631
NP_003359                                                              16    5631
NP_001017416                                                           16    5631
NP_001135758                                                           16    7355
NP_055754                                                              16    7355
NP_078900                                                              16    7355
XP_005258292                                                           16    7355
XP_006722483                                                           16    7355
XP_005258291                                                           16    7355
XP_005258290                                                           16    7355
XP_005262685                                                           16    7355
NP_001229658                                                           15    9605
NP_085135                                                              15    9605
NP_919289                                                              15    9605
XP_006725866                                                           15    9605
XP_005258413                                                           15    9605
XP_006716827                                                           15    9605
XP_005251508                                                           15    9605
XP_005251507                                                           15    9605
XP_006714307                                                           15    9605

>NP_689991
          Length = 518

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILTPLSMSM 9
           I+TPL+M M
Sbjct: 289 IITPLTMDM 297



>XP_005262955
          Length = 336

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILTPLSMSM 9
           I+TPL+M M
Sbjct: 289 IITPLTMDM 297



>XP_005262954
          Length = 451

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILTPLSMSM 9
           I+TPL+M M
Sbjct: 222 IITPLTMDM 230



>XP_005262953
          Length = 469

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILTPLSMSM 9
           I+TPL+M M
Sbjct: 240 IITPLTMDM 248



>XP_005262950
          Length = 518

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILTPLSMSM 9
           I+TPL+M M
Sbjct: 289 IITPLTMDM 297



>NP_001005471
          Length = 308

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILTPLSMSM 9
           +LTP++MS+
Sbjct: 158 LLTPITMSL 166



>NP_001017415
          Length = 785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILTPLSMSM 9
           +LTPL +S+
Sbjct: 556 LLTPLKLSL 564



>NP_003359
          Length = 785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILTPLSMSM 9
           +LTPL +S+
Sbjct: 556 LLTPLKLSL 564



>NP_001017416
          Length = 785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILTPLSMSM 9
           +LTPL +S+
Sbjct: 556 LLTPLKLSL 564



>NP_001135758
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ILTPLSMS 8
            +LTP SMS
Sbjct: 1047 LLTPQSMS 1054



>NP_055754
          Length = 1435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILTPLSMS 8
           +LTPLS S
Sbjct: 966 VLTPLSPS 973



>NP_078900
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ILTPLSMS 8
            +LTP SMS
Sbjct: 1047 LLTPQSMS 1054



>XP_005258292
          Length = 1161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILTPLSMS 8
           +LTPLS S
Sbjct: 692 VLTPLSPS 699



>XP_006722483
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILTPLSMS 8
           +LTPLS S
Sbjct: 967 VLTPLSPS 974



>XP_005258291
          Length = 1406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILTPLSMS 8
           +LTPLS S
Sbjct: 967 VLTPLSPS 974



>XP_005258290
          Length = 1436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILTPLSMS 8
           +LTPLS S
Sbjct: 967 VLTPLSPS 974



>XP_005262685
          Length = 1113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ILTPLSMS 8
            +LTP SMS
Sbjct: 1069 LLTPQSMS 1076



>NP_001229658
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ILTPLS 6
           ILTPLS
Sbjct: 419 ILTPLS 424



>NP_085135
          Length = 2248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILTPLSMS 8
           +LTPL +S
Sbjct: 183 VLTPLKVS 190



>NP_919289
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    ILTPLSMSM 9
            +++PL+MS+
Sbjct: 1048 LMSPLTMSL 1056



>XP_006725866
          Length = 223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTPLSMSM 9
           LTP+ MS+
Sbjct: 207 LTPVDMSL 214



>XP_005258413
          Length = 2249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILTPLSMS 8
           +LTPL +S
Sbjct: 184 VLTPLKVS 191



>XP_006716827
          Length = 910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILTPLSMSM 9
           +++PL+MS+
Sbjct: 590 LMSPLTMSL 598



>XP_005251508
          Length = 1007

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILTPLSMSM 9
           +++PL+MS+
Sbjct: 687 LMSPLTMSL 695



>XP_005251507
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILTPLSMSM 9
           +++PL+MS+
Sbjct: 759 LMSPLTMSL 767



>XP_006714307
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ILTPLS 6
           ILTPLS
Sbjct: 201 ILTPLS 206



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.129    0.335 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 524,044
Number of extensions: 425
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)