Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_570711                                                              19     665
NP_570712                                                              19     665
NP_570714                                                              19     665
NP_570713                                                              19     665
NP_570716                                                              19     665
NP_000235                                                              19     665
NP_570715                                                              19     665
XP_006718620                                                           19     665
XP_005274059                                                           19     665
XP_005274060                                                           19     665
XP_005274058                                                           19     665
XP_006726609                                                           17    3301
XP_006719787                                                           17    3301
XP_006710027                                                           17    3301
NP_001128472                                                           17    4312
NP_001128471                                                           17    4312
NP_006823                                                              17    4312
XP_005267342                                                           17    4312
XP_006720073                                                           17    4312
XP_006720072                                                           17    4312
XP_006720071                                                           17    4312
NP_000213                                                              16    5631
NP_001087241                                                           16    5631
NP_079333                                                              16    5631
XP_005268154                                                           16    5631
XP_005268150                                                           16    5631
XP_005268149                                                           16    5631
XP_005265799                                                           16    5631
XP_005265798                                                           16    5631
XP_005265797                                                           16    5631
NP_009179                                                              16    7355
NP_338599                                                              16    7355
NP_057465                                                              16    7355
NP_597720                                                              16    7355
NP_002075                                                              16    7355
NP_001271284                                                           16    7355
NP_005672                                                              16    7355
NP_001188465                                                           16    7355
NP_000166                                                              16    7355
NP_001276718                                                           16    7355
NP_001276719                                                           16    7355
NP_001171651                                                           16    7355
NP_647603                                                              16    7355
XP_006723211                                                           16    7355
XP_005258821                                                           16    7355
XP_005273400                                                           16    7355
XP_006711676                                                           16    7355
XP_006711675                                                           16    7355
NP_001269524                                                           15    9605
NP_067004                                                              15    9605
NP_001269519                                                           15    9605
NP_001269521                                                           15    9605
NP_001269523                                                           15    9605
NP_001269525                                                           15    9605
NP_055682                                                              15    9605
NP_001258468                                                           15    9605
XP_006725177                                                           15    9605
XP_006725176                                                           15    9605
XP_006725175                                                           15    9605
XP_006723715                                                           15    9605
XP_006716774                                                           15    9605
XP_005266102                                                           15    9605
XP_005266101                                                           15    9605
XP_005266100                                                           15    9605
XP_006712555                                                           15    9605
XP_006712554                                                           15    9605
XP_005263717                                                           15    9605
XP_005263716                                                           15    9605
XP_006712553                                                           15    9605
NP_115786                                                              15    9605
NP_997246                                                              15    9605
NP_001157956                                                           15    9605
>NP_570711
          Length = 610

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSFLKRQR 9
           LSFLKRQR
Sbjct: 600 LSFLKRQR 607
>NP_570712
          Length = 615

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSFLKRQR 9
           LSFLKRQR
Sbjct: 605 LSFLKRQR 612
>NP_570714
          Length = 615

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSFLKRQR 9
           LSFLKRQR
Sbjct: 605 LSFLKRQR 612
>NP_570713
          Length = 615

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSFLKRQR 9
           LSFLKRQR
Sbjct: 605 LSFLKRQR 612
>NP_570716
          Length = 615

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSFLKRQR 9
           LSFLKRQR
Sbjct: 605 LSFLKRQR 612
>NP_000235
          Length = 615

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSFLKRQR 9
           LSFLKRQR
Sbjct: 605 LSFLKRQR 612
>NP_570715
          Length = 615

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSFLKRQR 9
           LSFLKRQR
Sbjct: 605 LSFLKRQR 612
>XP_006718620
          Length = 610

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSFLKRQR 9
           LSFLKRQR
Sbjct: 600 LSFLKRQR 607
>XP_005274059
          Length = 610

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSFLKRQR 9
           LSFLKRQR
Sbjct: 600 LSFLKRQR 607
>XP_005274060
          Length = 610

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSFLKRQR 9
           LSFLKRQR
Sbjct: 600 LSFLKRQR 607
>XP_005274058
          Length = 610

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSFLKRQR 9
           LSFLKRQR
Sbjct: 600 LSFLKRQR 607
>XP_006726609
          Length = 2838

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    ILSFLKRQR 9
            ILS++KR+R
Sbjct: 1462 ILSYVKRKR 1470
>XP_006719787
          Length = 2838

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    ILSFLKRQR 9
            ILS++KR+R
Sbjct: 1462 ILSYVKRKR 1470
>XP_006710027
          Length = 2837

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    ILSFLKRQR 9
            ILS++KR+R
Sbjct: 1461 ILSYVKRKR 1469
>NP_001128472
          Length = 633

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ILSFLKRQ 8
           ILSFLK Q
Sbjct: 492 ILSFLKMQ 499
>NP_001128471
          Length = 687

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ILSFLKRQ 8
           ILSFLK Q
Sbjct: 492 ILSFLKMQ 499
>NP_006823
          Length = 680

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ILSFLKRQ 8
           ILSFLK Q
Sbjct: 492 ILSFLKMQ 499
>XP_005267342
          Length = 691

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ILSFLKRQ 8
           ILSFLK Q
Sbjct: 503 ILSFLKMQ 510
>XP_006720073
          Length = 695

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ILSFLKRQ 8
           ILSFLK Q
Sbjct: 492 ILSFLKMQ 499
>XP_006720072
          Length = 698

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ILSFLKRQ 8
           ILSFLK Q
Sbjct: 503 ILSFLKMQ 510
>XP_006720071
          Length = 706

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ILSFLKRQ 8
           ILSFLK Q
Sbjct: 503 ILSFLKMQ 510
>NP_000213
          Length = 976

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILSFLKRQR 9
           +L+FL+R+R
Sbjct: 678 LLNFLRRKR 686
>NP_001087241
          Length = 972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILSFLKRQR 9
           +L+FL+R+R
Sbjct: 674 LLNFLRRKR 682
>NP_079333
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  ILSFLKRQ 8
          +LS+LK+Q
Sbjct: 81 VLSYLKKQ 88
>XP_005268154
          Length = 352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  ILSFLKRQ 8
          +LS+LK+Q
Sbjct: 81 VLSYLKKQ 88
>XP_005268150
          Length = 517

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  ILSFLKRQ 8
          +LS+LK+Q
Sbjct: 81 VLSYLKKQ 88
>XP_005268149
          Length = 565

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  ILSFLKRQ 8
          +LS+LK+Q
Sbjct: 81 VLSYLKKQ 88
>XP_005265799
          Length = 973

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILSFLKRQR 9
           +L+FL+R+R
Sbjct: 675 LLNFLRRKR 683
>XP_005265798
          Length = 976

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILSFLKRQR 9
           +L+FL+R+R
Sbjct: 679 LLNFLRRKR 687
>XP_005265797
          Length = 977

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILSFLKRQR 9
           +L+FL+R+R
Sbjct: 679 LLNFLRRKR 687
>NP_009179
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILSFLKRQ 8
           +L+FL+RQ
Sbjct: 98  LLAFLRRQ 105
>NP_338599
          Length = 314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILSFLKRQ 8
           +L+FL+RQ
Sbjct: 108 LLAFLRRQ 115
>NP_057465
          Length = 369

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILSFLKRQ 8
           +L+FL+RQ
Sbjct: 163 LLAFLRRQ 170
>NP_597720
          Length = 498

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILSFLKRQR 9
           ILSFLK  +
Sbjct: 160 ILSFLKNNK 168
>NP_002075
          Length = 226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILSFLKRQ 8
           ILS+++RQ
Sbjct: 211 ILSYMRRQ 218
>NP_001271284
          Length = 297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILSFLKRQR 9
           ILSFLK  +
Sbjct: 160 ILSFLKNNK 168
>NP_005672
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILSFLKRQR 9
           + +FLKRQ+
Sbjct: 279 LYNFLKRQK 287
>NP_001188465
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILSFLKRQR 9
           + +FLKRQ+
Sbjct: 279 LYNFLKRQK 287
>NP_000166
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILSFLKRQR 9
           +++F+K+QR
Sbjct: 545 LINFIKQQR 553
>NP_001276718
          Length = 597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILSFLKRQR 9
           +++F+K+QR
Sbjct: 584 LINFIKQQR 592
>NP_001276719
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILSFLKRQR 9
           +++F+K+QR
Sbjct: 517 LINFIKQQR 525
>NP_001171651
          Length = 569

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILSFLKRQR 9
           +++F+K+QR
Sbjct: 556 LINFIKQQR 564
>NP_647603
          Length = 336

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILSFLKRQR 9
           + +FLKRQ+
Sbjct: 165 LYNFLKRQK 173
>XP_006723211
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILSFLKRQR 9
           +++F+K+QR
Sbjct: 545 LINFIKQQR 553
>XP_005258821
          Length = 558

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILSFLKRQR 9
           +++F+K+QR
Sbjct: 545 LINFIKQQR 553
>XP_005273400
          Length = 311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILSFLKRQR 9
           + +FLKRQ+
Sbjct: 279 LYNFLKRQK 287
>XP_006711676
          Length = 336

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILSFLKRQR 9
           + +FLKRQ+
Sbjct: 165 LYNFLKRQK 173
>XP_006711675
          Length = 412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILSFLKRQR 9
           + +FLKRQ+
Sbjct: 241 LYNFLKRQK 249
>NP_001269524
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSFLKRQR 9
           L FLKR+R
Sbjct: 113 LWFLKRER 120
>NP_067004
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSFLKRQR 9
           L FLKR+R
Sbjct: 247 LWFLKRER 254
>NP_001269519
          Length = 228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSFLKRQR 9
           L FLKR+R
Sbjct: 140 LWFLKRER 147
>NP_001269521
          Length = 296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSFLKRQR 9
           L FLKR+R
Sbjct: 247 LWFLKRER 254
>NP_001269523
          Length = 241

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSFLKRQR 9
           L FLKR+R
Sbjct: 153 LWFLKRER 160
>NP_001269525
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSFLKRQR 9
           L FLKR+R
Sbjct: 140 LWFLKRER 147
>NP_055682
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILSFLKRQR 9
           +LS  KRQR
Sbjct: 239 VLSAAKRQR 247
>NP_001258468
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LSFLKRQR 9
           L+FLK++R
Sbjct: 471 LTFLKKRR 478
>XP_006725177
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILSFLKRQR 9
           +LS  KRQR
Sbjct: 239 VLSAAKRQR 247
>XP_006725176
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILSFLKRQR 9
           +LS  KRQR
Sbjct: 239 VLSAAKRQR 247
>XP_006725175
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILSFLKRQR 9
           +LS  KRQR
Sbjct: 239 VLSAAKRQR 247
>XP_006723715
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LSFLKRQR 9
           L+FLK++R
Sbjct: 471 LTFLKKRR 478
>XP_006716774
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILSFLKRQR 9
           +L+FL+R R
Sbjct: 163 VLAFLRRWR 171
>XP_005266102
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILSFLKRQR 9
           +LS  KRQR
Sbjct: 239 VLSAAKRQR 247
>XP_005266101
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILSFLKRQR 9
           +LS  KRQR
Sbjct: 239 VLSAAKRQR 247
>XP_005266100
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILSFLKRQR 9
           +LS  KRQR
Sbjct: 239 VLSAAKRQR 247
>XP_006712555
          Length = 1786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SFLKRQR 9
           SF+K+QR
Sbjct: 483 SFIKQQR 489
>XP_006712554
          Length = 1885

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SFLKRQR 9
           SF+K+QR
Sbjct: 582 SFIKQQR 588
>XP_005263717
          Length = 1953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SFLKRQR 9
           SF+K+QR
Sbjct: 650 SFIKQQR 656
>XP_005263716
          Length = 1953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SFLKRQR 9
           SF+K+QR
Sbjct: 650 SFIKQQR 656
>XP_006712553
          Length = 1953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SFLKRQR 9
           SF+K+QR
Sbjct: 650 SFIKQQR 656
>NP_115786
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SFLKRQR 9
           SFL RQR
Sbjct: 693 SFLARQR 699
>NP_997246
          Length = 1909

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SFLKRQR 9
           SF+K+QR
Sbjct: 650 SFIKQQR 656
>NP_001157956
          Length = 283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FLKRQR 9
           F+KRQR
Sbjct: 143 FIKRQR 148
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.346    0.153    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 503,723
Number of extensions: 863
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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