Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           20     509
NP_004561                                                              20     509
NP_001275703                                                           20     509
XP_005253450                                                           20     509
XP_006719151                                                           20     509
NP_003733                                                              17    3301
NP_775945                                                              17    3301
XP_006715526                                                           17    3301
XP_005266998                                                           17    3301
XP_006712881                                                           17    3301
XP_006712880                                                           17    3301
NP_000353                                                              17    4312
NP_000042                                                              16    5631
NP_006314                                                              16    5631
XP_006718908                                                           16    5631
XP_005271621                                                           16    5631
XP_006718907                                                           16    5631
XP_006718906                                                           16    5631
XP_005271619                                                           16    5631
XP_005271618                                                           16    5631
XP_005262746                                                           16    5631
XP_005262745                                                           16    5631
NP_115495                                                              16    7355
NP_001127854                                                           16    7355
NP_001139317                                                           16    7355
NP_598334                                                              16    7355
NP_002932                                                              16    7355
NP_055684                                                              16    7355
NP_001364                                                              16    7355
NP_060259                                                              16    7355
NP_001164209                                                           16    7355
XP_006713341                                                           16    7355
XP_006713340                                                           16    7355
XP_006713339                                                           16    7355
XP_006712669                                                           16    7355
XP_006711798                                                           16    7355
NP_056047                                                              16    7355
NP_006761                                                              15    9605
NP_620686                                                              15    9605
NP_653200                                                              15    9605
NP_001167574                                                           15    9605
NP_055520                                                              15    9605
NP_001036199                                                           15    9605
NP_110445                                                              15    9605
NP_001104595                                                           15    9605
NP_036533                                                              15    9605
NP_116098                                                              15    9605
XP_005276778                                                           15    9605
XP_005276777                                                           15    9605
XP_005274830                                                           15    9605
XP_005262408                                                           15    9605
XP_006724647                                                           15    9605
XP_006724646                                                           15    9605
XP_006724645                                                           15    9605
XP_006724644                                                           15    9605
XP_006724643                                                           15    9605
XP_006724642                                                           15    9605
XP_005261968                                                           15    9605
XP_005261966                                                           15    9605
XP_005261967                                                           15    9605
XP_006724476                                                           15    9605
XP_005261965                                                           15    9605
XP_006722977                                                           15    9605
XP_005260143                                                           15    9605
XP_005260145                                                           15    9605
XP_005260142                                                           15    9605
XP_005260144                                                           15    9605
XP_006718108                                                           15    9605
XP_006716252                                                           15    9605
XP_006716251                                                           15    9605
XP_005262748                                                           15    9605
XP_005276172                                                           15    9605
NP_055890                                                              15    9605
NP_443073                                                              15    9605
>NP_001275701
          Length = 1486

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ILQRKGVNF 9
           ILQRKG NF
Sbjct: 459 ILQRKGENF 467
>NP_004561
          Length = 1445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ILQRKGVNF 9
           ILQRKG NF
Sbjct: 459 ILQRKGENF 467
>NP_001275703
          Length = 1264

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ILQRKGVNF 9
           ILQRKG NF
Sbjct: 237 ILQRKGENF 245
>XP_005253450
          Length = 1486

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ILQRKGVNF 9
           ILQRKG NF
Sbjct: 459 ILQRKGENF 467
>XP_006719151
          Length = 1486

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ILQRKGVNF 9
           ILQRKG NF
Sbjct: 459 ILQRKGENF 467
>NP_003733
          Length = 1321

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILQRKGVNF 9
           +L+RKGV F
Sbjct: 643 LLERKGVYF 651
>NP_775945
          Length = 539

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           +LQRKG++
Sbjct: 219 VLQRKGIS 226
>XP_006715526
          Length = 543

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           +LQRKG++
Sbjct: 266 VLQRKGIS 273
>XP_005266998
          Length = 762

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           +LQRKG++
Sbjct: 266 VLQRKGIS 273
>XP_006712881
          Length = 1335

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILQRKGVNF 9
           +L+RKGV F
Sbjct: 657 LLERKGVYF 665
>XP_006712880
          Length = 1335

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILQRKGVNF 9
           +L+RKGV F
Sbjct: 657 LLERKGVYF 665
>NP_000353
          Length = 211

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QRKGVNF 9
           QRKG+N+
Sbjct: 131 QRKGLNY 137
>NP_000042
          Length = 3056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QRKGVN 8
            QRKG+N
Sbjct: 2641 QRKGIN 2646
>NP_006314
          Length = 1268

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILQRKGVNF 9
           +LQ+KGV +
Sbjct: 349 LLQQKGVQY 357
>XP_006718908
          Length = 1708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QRKGVN 8
            QRKG+N
Sbjct: 1293 QRKGIN 1298
>XP_005271621
          Length = 2708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QRKGVN 8
            QRKG+N
Sbjct: 2293 QRKGIN 2298
>XP_006718907
          Length = 3050

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QRKGVN 8
            QRKG+N
Sbjct: 2635 QRKGIN 2640
>XP_006718906
          Length = 3056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QRKGVN 8
            QRKG+N
Sbjct: 2641 QRKGIN 2646
>XP_005271619
          Length = 3056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QRKGVN 8
            QRKG+N
Sbjct: 2641 QRKGIN 2646
>XP_005271618
          Length = 3056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3    QRKGVN 8
            QRKG+N
Sbjct: 2641 QRKGIN 2646
>XP_005262746
          Length = 1298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILQRKGVNF 9
           +LQ+KGV +
Sbjct: 380 LLQQKGVQY 388
>XP_005262745
          Length = 1299

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILQRKGVNF 9
           +LQ+KGV +
Sbjct: 380 LLQQKGVQY 388
>NP_115495
          Length = 6306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    ILQRKGVN 8
            +LQ+ GVN
Sbjct: 5418 VLQKDGVN 5425
>NP_001127854
          Length = 1114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           +LQRKG++
Sbjct: 549 LLQRKGLS 556
>NP_001139317
          Length = 1551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RKGVNF 9
           RKGVN+
Sbjct: 706 RKGVNY 711
>NP_598334
          Length = 1606

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RKGVNF 9
           RKGVN+
Sbjct: 706 RKGVNY 711
>NP_002932
          Length = 1651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RKGVNF 9
           RKGVN+
Sbjct: 742 RKGVNY 747
>NP_055684
          Length = 963

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           +LQRKG++
Sbjct: 563 LLQRKGLS 570
>NP_001364
          Length = 4515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    LQRKGVN 8
            LQR GVN
Sbjct: 3806 LQRTGVN 3812
>NP_060259
          Length = 833

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILQRKGVNF 9
           +L +KG NF
Sbjct: 412 LLVKKGTNF 420
>NP_001164209
          Length = 1182

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           +LQRKG++
Sbjct: 690 LLQRKGLS 697
>XP_006713341
          Length = 1600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RKGVNF 9
           RKGVN+
Sbjct: 691 RKGVNY 696
>XP_006713340
          Length = 1615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RKGVNF 9
           RKGVN+
Sbjct: 706 RKGVNY 711
>XP_006713339
          Length = 1616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RKGVNF 9
           RKGVN+
Sbjct: 707 RKGVNY 712
>XP_006712669
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILQRKGVNF 9
           +L +KG NF
Sbjct: 454 LLVKKGTNF 462
>XP_006711798
          Length = 4586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    LQRKGVN 8
            LQR GVN
Sbjct: 3868 LQRTGVN 3874
>NP_056047
          Length = 759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           +LQRKG++
Sbjct: 387 LLQRKGLS 394
>NP_006761
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  QRKGVNF 9
          +R GVNF
Sbjct: 38 RRNGVNF 44
>NP_620686
          Length = 950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ILQRKGV 7
           +LQR+GV
Sbjct: 156 LLQRRGV 162
>NP_653200
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  ILQRKGV 7
          +LQ+KG+
Sbjct: 47 VLQKKGI 53
>NP_001167574
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILQRKGVNF 9
           +LQ++ VNF
Sbjct: 368 LLQKQPVNF 376
>NP_055520
          Length = 1966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ILQRKGV 7
            +LQR+GV
Sbjct: 1394 VLQREGV 1400
>NP_001036199
          Length = 1233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           +LQ+KGV+
Sbjct: 349 LLQQKGVD 356
>NP_110445
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3 QRKGVN 8
         +RKGVN
Sbjct: 3 ERKGVN 8
>NP_001104595
          Length = 1488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           IL+RKG++
Sbjct: 792 ILERKGLS 799
>NP_036533
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILQRKGVN 8
           +LQR G+N
Sbjct: 384 VLQRGGLN 391
>NP_116098
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  LQRKGVN 8
          LQR GVN
Sbjct: 53 LQRLGVN 59
>XP_005276778
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ILQRKG 6
           +LQRKG
Sbjct: 119 VLQRKG 124
>XP_005276777
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ILQRKG 6
           +LQRKG
Sbjct: 119 VLQRKG 124
>XP_005274830
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ILQRKG 6
           +LQRKG
Sbjct: 119 VLQRKG 124
>XP_005262408
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ILQRKG 6
           +LQRKG
Sbjct: 119 VLQRKG 124
>XP_006724647
          Length = 1186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           IL+RKG++
Sbjct: 824 ILERKGLS 831
>XP_006724646
          Length = 1200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           IL+RKG++
Sbjct: 824 ILERKGLS 831
>XP_006724645
          Length = 1212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           IL+RKG++
Sbjct: 824 ILERKGLS 831
>XP_006724644
          Length = 1244

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           IL+RKG++
Sbjct: 824 ILERKGLS 831
>XP_006724643
          Length = 1283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           IL+RKG++
Sbjct: 587 ILERKGLS 594
>XP_006724642
          Length = 1520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           IL+RKG++
Sbjct: 824 ILERKGLS 831
>XP_005261968
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILQRKGVN 8
           +LQR G+N
Sbjct: 384 VLQRGGLN 391
>XP_005261966
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILQRKGVN 8
           +LQR G+N
Sbjct: 384 VLQRGGLN 391
>XP_005261967
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILQRKGVN 8
           +LQR G+N
Sbjct: 384 VLQRGGLN 391
>XP_006724476
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILQRKGVN 8
           +LQR G+N
Sbjct: 384 VLQRGGLN 391
>XP_005261965
          Length = 1920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILQRKGVN 8
           +LQR G+N
Sbjct: 466 VLQRGGLN 473
>XP_006722977
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3 QRKGVN 8
         +RKGVN
Sbjct: 3 ERKGVN 8
>XP_005260143
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3 QRKGVN 8
         +RKGVN
Sbjct: 3 ERKGVN 8
>XP_005260145
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3 QRKGVN 8
         +RKGVN
Sbjct: 3 ERKGVN 8
>XP_005260142
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3 QRKGVN 8
         +RKGVN
Sbjct: 3 ERKGVN 8
>XP_005260144
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3 QRKGVN 8
         +RKGVN
Sbjct: 3 ERKGVN 8
>XP_006718108
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  LQRKGVN 8
          LQR GVN
Sbjct: 53 LQRLGVN 59
>XP_006716252
          Length = 1937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ILQRKGV 7
            +LQR+GV
Sbjct: 1403 VLQREGV 1409
>XP_006716251
          Length = 1975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ILQRKGV 7
            +LQR+GV
Sbjct: 1403 VLQREGV 1409
>XP_005262748
          Length = 1263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           +LQ+KGV+
Sbjct: 380 LLQQKGVD 387
>XP_005276172
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ILQRKG 6
           +LQRKG
Sbjct: 119 VLQRKG 124
>NP_055890
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILQRKGVN 8
           IL+RKG++
Sbjct: 587 ILERKGLS 594
>NP_443073
          Length = 268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QRKGVNF 9
           Q+KGV+F
Sbjct: 222 QQKGVSF 228
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.153    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 525,031
Number of extensions: 726
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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