Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              20     509
NP_000422                                                              18    1935
XP_005253941                                                           18    1935
XP_005253940                                                           18    1935
NP_001107657                                                           18    1935
NP_002411                                                              17    3301
NP_001238953                                                           17    3301
NP_001238949                                                           17    3301
NP_079247                                                              17    3301
NP_001007472                                                           17    3301
NP_066003                                                              17    3301
NP_996830                                                              17    3301
NP_996829                                                              17    3301
NP_996828                                                              17    3301
NP_996827                                                              17    3301
XP_005252275                                                           17    3301
NP_066997                                                              17    4312
NP_065820                                                              17    4312
NP_003611                                                              16    5631
NP_055844                                                              16    5631
NP_001139332                                                           16    5631
NP_115666                                                              16    5631
XP_006714783                                                           16    5631
XP_005272170                                                           16    5631
NP_001139333                                                           16    5631
NP_950251                                                              16    7355
NP_056315                                                              16    7355
NP_055889                                                              16    7355
NP_904325                                                              16    7355
NP_002255                                                              16    7355
NP_001243638                                                           16    7355
NP_057367                                                              16    7355
NP_898884                                                              16    7355
XP_005261164                                                           16    7355
XP_005261166                                                           16    7355
XP_005261163                                                           16    7355
XP_006714124                                                           16    7355
XP_006714122                                                           16    7355
XP_006714121                                                           16    7355
XP_005247494                                                           16    7355
XP_006713666                                                           16    7355
XP_006713665                                                           16    7355
NP_079023                                                              15    9605
NP_000651                                                              15    9605
NP_001240841                                                           15    9605
NP_055988                                                              15    9605
NP_056374                                                              15    9605
NP_001123582                                                           15    9605
NP_065784                                                              15    9605
XP_006722501                                                           15    9605
XP_005258301                                                           15    9605
XP_005258300                                                           15    9605
XP_006722001                                                           15    9605
XP_006722000                                                           15    9605
XP_006721999                                                           15    9605
XP_006721998                                                           15    9605
XP_006721997                                                           15    9605
XP_006721996                                                           15    9605
XP_006721995                                                           15    9605
XP_006714064                                                           15    9605
XP_005262708                                                           15    9605
XP_005262706                                                           15    9605
XP_006714063                                                           15    9605
XP_005262705                                                           15    9605
XP_006714062                                                           15    9605
XP_005262704                                                           15    9605
XP_005262703                                                           15    9605
XP_005247723                                                           15    9605
NP_057423                                                              15    9605
NP_002535                                                              15    9605
>NP_004295
          Length = 1620

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ILLMSTPGK 9
           ILLM TPGK
Sbjct: 375 ILLMPTPGK 383
>NP_000422
          Length = 396

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILLMSTPGK 9
          +LL+S PGK
Sbjct: 5  VLLVSAPGK 13
>XP_005253941
          Length = 344

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILLMSTPGK 9
          +LL+S PGK
Sbjct: 5  VLLVSAPGK 13
>XP_005253940
          Length = 396

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILLMSTPGK 9
          +LL+S PGK
Sbjct: 5  VLLVSAPGK 13
>NP_001107657
          Length = 396

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILLMSTPGK 9
          +LL+S PGK
Sbjct: 5  VLLVSAPGK 13
>NP_002411
          Length = 1603

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMSTPGK 9
           +LMS PGK
Sbjct: 879 ILMSEPGK 886
>NP_001238953
          Length = 1625

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMSTPGK 9
           +LMS PGK
Sbjct: 901 ILMSEPGK 908
>NP_001238949
          Length = 1642

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMSTPGK 9
           +LMS PGK
Sbjct: 918 ILMSEPGK 925
>NP_079247
          Length = 1566

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMSTPGK 9
           +LMS PGK
Sbjct: 780 ILMSEPGK 787
>NP_001007472
          Length = 1707

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMSTPGK 9
           +LMS PGK
Sbjct: 921 ILMSEPGK 928
>NP_066003
          Length = 1554

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMSTPGK 9
           +LMS PGK
Sbjct: 768 ILMSEPGK 775
>NP_996830
          Length = 1569

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMSTPGK 9
           +LMS PGK
Sbjct: 783 ILMSEPGK 790
>NP_996829
          Length = 1579

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMSTPGK 9
           +LMS PGK
Sbjct: 793 ILMSEPGK 800
>NP_996828
          Length = 1556

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMSTPGK 9
           +LMS PGK
Sbjct: 770 ILMSEPGK 777
>NP_996827
          Length = 1544

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMSTPGK 9
           +LMS PGK
Sbjct: 758 ILMSEPGK 765
>XP_005252275
          Length = 1734

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMSTPGK 9
           +LMS PGK
Sbjct: 948 ILMSEPGK 955
>NP_066997
          Length = 923

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLMSTPG 8
           +LL+S+PG
Sbjct: 310 VLLLSSPG 317
>NP_065820
          Length = 1388

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLMSTPG 8
           LLMS+PG
Sbjct: 310 LLMSSPG 316
>NP_003611
          Length = 605

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLMSTPGK 9
           L MSTPG+
Sbjct: 513 LKMSTPGQ 520
>NP_055844
          Length = 1024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILLMSTPGK 9
           ILL+  PGK
Sbjct: 597 ILLIQQPGK 605
>NP_001139332
          Length = 1024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILLMSTPGK 9
           ILL+  PGK
Sbjct: 597 ILLIQQPGK 605
>NP_115666
          Length = 1058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILLMSTPG 8
           ILL+S PG
Sbjct: 824 ILLLSLPG 831
>XP_006714783
          Length = 599

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILLMSTPG 8
           ILL+S PG
Sbjct: 365 ILLLSLPG 372
>XP_005272170
          Length = 1058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILLMSTPG 8
           ILL+S PG
Sbjct: 824 ILLLSLPG 831
>NP_001139333
          Length = 1024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILLMSTPGK 9
           ILL+  PGK
Sbjct: 597 ILLIQQPGK 605
>NP_950251
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLMSTPG 8
           +LL+S PG
Sbjct: 117 VLLLSEPG 124
>NP_056315
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLMSTPG 8
           +LL+S PG
Sbjct: 272 VLLLSEPG 279
>NP_055889
          Length = 1770

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LMSTPG 8
           +MSTPG
Sbjct: 418 IMSTPG 423
>NP_904325
          Length = 1153

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LMSTPG 8
           +MSTPG
Sbjct: 418 IMSTPG 423
>NP_002255
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 MSTPGK 9
         M+TPGK
Sbjct: 1 MTTPGK 6
>NP_001243638
          Length = 196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ILLMSTPGK 9
          IL M+TP K
Sbjct: 9  ILKMTTPNK 17
>NP_057367
          Length = 172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  ILLMSTPG 8
          ILL  TPG
Sbjct: 6  ILLTGTPG 13
>NP_898884
          Length = 1177

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILLMSTPG 8
           ILL+S PG
Sbjct: 107 ILLISIPG 114
>XP_005261164
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLMSTPG 8
           +LL+S PG
Sbjct: 117 VLLLSEPG 124
>XP_005261166
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLMSTPG 8
           +LL+S PG
Sbjct: 117 VLLLSEPG 124
>XP_005261163
          Length = 614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLMSTPG 8
           +LL+S PG
Sbjct: 190 VLLLSEPG 197
>XP_006714124
          Length = 113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ILLMSTPGK 9
          IL M+TP K
Sbjct: 28 ILKMTTPNK 36
>XP_006714122
          Length = 196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ILLMSTPGK 9
          IL M+TP K
Sbjct: 9  ILKMTTPNK 17
>XP_006714121
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ILLMSTPGK 9
          IL M+TP K
Sbjct: 28 ILKMTTPNK 36
>XP_005247494
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4 MSTPGK 9
         M+TPGK
Sbjct: 1 MTTPGK 6
>XP_006713666
          Length = 1104

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ILLMSTPG 8
          ILL+S PG
Sbjct: 34 ILLISIPG 41
>XP_006713665
          Length = 1175

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILLMSTPG 8
           ILL+S PG
Sbjct: 107 ILLISIPG 114
>NP_079023
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILLMSTPGK 9
           +LL+ +PGK
Sbjct: 215 VLLIWSPGK 223
>NP_000651
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ILLMSTP 7
           +LLM+TP
Sbjct: 258 LLLMATP 264
>NP_001240841
          Length = 1159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LMSTPGK 9
           ++STPG+
Sbjct: 871 MLSTPGR 877
>NP_055988
          Length = 1168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LMSTPGK 9
           ++STPG+
Sbjct: 777 MLSTPGR 783
>NP_056374
          Length = 1596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  LMSTPG 8
          L+STPG
Sbjct: 38 LLSTPG 43
>NP_001123582
          Length = 242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  LMSTPG 8
          L+STPG
Sbjct: 38 LLSTPG 43
>NP_065784
          Length = 1381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LMSTPG 8
           LM+TPG
Sbjct: 853 LMTTPG 858
>XP_006722501
          Length = 1403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  LMSTPG 8
          L+STPG
Sbjct: 38 LLSTPG 43
>XP_005258301
          Length = 1539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  LMSTPG 8
          L+STPG
Sbjct: 38 LLSTPG 43
>XP_005258300
          Length = 1596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  LMSTPG 8
          L+STPG
Sbjct: 38 LLSTPG 43
>XP_006722001
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   ILLMSTPGK 9
           +LL   PGK
Sbjct: 213 VLLCEAPGK 221
>XP_006722000
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   ILLMSTPGK 9
           +LL   PGK
Sbjct: 277 VLLCEAPGK 285
>XP_006721999
          Length = 493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   ILLMSTPGK 9
           +LL   PGK
Sbjct: 314 VLLCEAPGK 322
>XP_006721998
          Length = 493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   ILLMSTPGK 9
           +LL   PGK
Sbjct: 314 VLLCEAPGK 322
>XP_006721997
          Length = 493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   ILLMSTPGK 9
           +LL   PGK
Sbjct: 314 VLLCEAPGK 322
>XP_006721996
          Length = 511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   ILLMSTPGK 9
           +LL   PGK
Sbjct: 332 VLLCEAPGK 340
>XP_006721995
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   ILLMSTPGK 9
           +LL   PGK
Sbjct: 483 VLLCEAPGK 491
>XP_006714064
          Length = 546

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LMSTPGK 9
           ++STPG+
Sbjct: 155 MLSTPGR 161
>XP_005262708
          Length = 1039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LMSTPGK 9
           ++STPG+
Sbjct: 648 MLSTPGR 654
>XP_005262706
          Length = 1146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LMSTPGK 9
           ++STPG+
Sbjct: 755 MLSTPGR 761
>XP_006714063
          Length = 1168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LMSTPGK 9
           ++STPG+
Sbjct: 777 MLSTPGR 783
>XP_005262705
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LMSTPGK 9
           ++STPG+
Sbjct: 790 MLSTPGR 796
>XP_006714062
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LMSTPGK 9
           ++STPG+
Sbjct: 871 MLSTPGR 877
>XP_005262704
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LMSTPGK 9
           ++STPG+
Sbjct: 871 MLSTPGR 877
>XP_005262703
          Length = 1275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LMSTPGK 9
           ++STPG+
Sbjct: 884 MLSTPGR 890
>XP_005247723
          Length = 1481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LMSTPG 8
           LM+TPG
Sbjct: 953 LMTTPG 958
>NP_057423
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   ILLMSTPGK 9
           +LL   PGK
Sbjct: 277 VLLCEAPGK 285
>NP_002535
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  ILLMSTPG 8
          ILL  TPG
Sbjct: 14 ILLFLTPG 21
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.139    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 867,788
Number of extensions: 767
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package