Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_060142                                                              17    3301
NP_060527                                                              17    3301
NP_877499                                                              17    3301
XP_006720645                                                           17    3301
XP_005254546                                                           17    3301
XP_005254545                                                           17    3301
XP_005254544                                                           17    3301
XP_005254543                                                           17    3301
XP_005246213                                                           17    3301
XP_006711941                                                           17    3301
XP_006711940                                                           17    3301
XP_006711939                                                           17    3301
NP_036476                                                              17    3301
NP_001030014                                                           17    3301
NP_000876                                                              17    4312
NP_001010898                                                           17    4312
NP_783165                                                              17    4312
XP_006710706                                                           17    4312
NP_057264                                                              16    5631
NP_003728                                                              16    5631
NP_001012527                                                           16    5631
NP_002410                                                              16    5631
XP_005253264                                                           16    5631
XP_005248368                                                           16    5631
NP_001167630                                                           16    7355
NP_071354                                                              16    7355
NP_001167631                                                           16    7355
NP_001230097                                                           16    7355
NP_631900                                                              16    7355
NP_777377                                                              16    7355
NP_057594                                                              16    7355
NP_001230098                                                           16    7355
NP_001230099                                                           16    7355
XP_005259737                                                           16    7355
XP_006716441                                                           16    7355
NP_612153                                                              16    7355
NP_001161870                                                           15    9605
NP_001120916                                                           15    9605
NP_001001547                                                           15    9605
NP_000063                                                              15    9605
NP_006407                                                              15    9605
NP_001001548                                                           15    9605
NP_001120915                                                           15    9605
NP_001276838                                                           15    9605
NP_001276837                                                           15    9605
NP_004922                                                              15    9605
NP_001276840                                                           15    9605
NP_757362                                                              15    9605
NP_742099                                                              15    9605
NP_647479                                                              15    9605
NP_758963                                                              15    9605
NP_057062                                                              15    9605
NP_056222                                                              15    9605
NP_001269596                                                           15    9605
NP_001269595                                                           15    9605
NP_001106279                                                           15    9605
NP_001186256                                                           15    9605
NP_003096                                                              15    9605
XP_006726853                                                           15    9605
XP_006723596                                                           15    9605
XP_005253308                                                           15    9605
XP_005250772                                                           15    9605
XP_005250771                                                           15    9605
XP_005250770                                                           15    9605
XP_005244926                                                           15    9605
NP_001956                                                              15    9605
NP_001138526                                                           15    9605
>NP_060142
          Length = 1865

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ILLLSIGVP 9
            ++LLS GVP
Sbjct: 1009 LVLLSFGVP 1017
>NP_060527
          Length = 289

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILLLSIGVP 9
           ILL+ IG+P
Sbjct: 105 ILLMVIGIP 113
>NP_877499
          Length = 730

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILLLSIGVP 9
           ILL+ IG+P
Sbjct: 105 ILLMVIGIP 113
>XP_006720645
          Length = 1060

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ILLLSIGVP 9
            ++LLS GVP
Sbjct: 1009 LVLLSFGVP 1017
>XP_005254546
          Length = 1443

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILLLSIGVP 9
           ++LLS GVP
Sbjct: 567 LVLLSFGVP 575
>XP_005254545
          Length = 1864

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ILLLSIGVP 9
            ++LLS GVP
Sbjct: 1009 LVLLSFGVP 1017
>XP_005254544
          Length = 1884

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ILLLSIGVP 9
            ++LLS GVP
Sbjct: 1009 LVLLSFGVP 1017
>XP_005254543
          Length = 1885

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ILLLSIGVP 9
            ++LLS GVP
Sbjct: 1009 LVLLSFGVP 1017
>XP_005246213
          Length = 250

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILLLSIGVP 9
          +LLL +GVP
Sbjct: 80 LLLLLVGVP 88
>XP_006711941
          Length = 294

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILLLSIGVP 9
          +LLL +GVP
Sbjct: 80 LLLLLVGVP 88
>XP_006711940
          Length = 319

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILLLSIGVP 9
          +LLL +GVP
Sbjct: 80 LLLLLVGVP 88
>XP_006711939
          Length = 322

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILLLSIGVP 9
          +LLL +GVP
Sbjct: 80 LLLLLVGVP 88
>NP_036476
          Length = 410

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILLLSIGVP 9
          +LLL +GVP
Sbjct: 80 LLLLLVGVP 88
>NP_001030014
          Length = 767

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LLLSIGVP 9
           LLL IGVP
Sbjct: 432 LLLHIGVP 439
>NP_000876
          Length = 1032

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILLLSIGVP 9
          +LLL +GVP
Sbjct: 21 MLLLCLGVP 29
>NP_001010898
          Length = 727

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILLLSIGVP 9
           +LL+ IG+P
Sbjct: 104 VLLIIIGIP 112
>NP_783165
          Length = 576

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILLLSIGVP 9
          +LLL +GVP
Sbjct: 21 LLLLLLGVP 29
>XP_006710706
          Length = 727

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILLLSIGVP 9
           +LL+ IG+P
Sbjct: 104 VLLIIIGIP 112
>NP_057264
          Length = 530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LLLSIGVP 9
          +LLS+G+P
Sbjct: 59 VLLSVGLP 66
>NP_003728
          Length = 3298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ILLLSIGVP 9
          +LLL  GVP
Sbjct: 30 LLLLGAGVP 38
>NP_001012527
          Length = 460

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LLLSIGVP 9
          +LLS+G+P
Sbjct: 59 VLLSVGLP 66
>NP_002410
          Length = 847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LLLSIGVP 9
           LLL +G+P
Sbjct: 712 LLLDLGIP 719
>XP_005253264
          Length = 3443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILLLSIGVP 9
           +LLL  GVP
Sbjct: 175 LLLLGAGVP 183
>XP_005248368
          Length = 243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LLLSIGVP 9
          +LLS+G+P
Sbjct: 59 VLLSVGLP 66
>NP_001167630
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLLSIGVP 9
           LLLS G+P
Sbjct: 360 LLLSTGMP 367
>NP_071354
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLLSIGVP 9
           LLLS G+P
Sbjct: 360 LLLSTGMP 367
>NP_001167631
          Length = 409

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLLSIGVP 9
           LLLS G+P
Sbjct: 315 LLLSTGMP 322
>NP_001230097
          Length = 296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ILLLSIGVP 9
          +LLL++G P
Sbjct: 7  LLLLALGCP 15
>NP_631900
          Length = 120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LLLSIGVP 9
          LLL++G+P
Sbjct: 8  LLLALGLP 15
>NP_777377
          Length = 123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LLLSIGVP 9
          LLL++G+P
Sbjct: 8  LLLALGLP 15
>NP_057594
          Length = 453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLLSIGVP 9
           +LLS GVP
Sbjct: 407 VLLSYGVP 414
>NP_001230098
          Length = 256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ILLLSIGVP 9
          +LLL++G P
Sbjct: 7  LLLLALGCP 15
>NP_001230099
          Length = 174

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ILLLSIGVP 9
          +LLL++G P
Sbjct: 7  LLLLALGCP 15
>XP_005259737
          Length = 120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LLLSIGVP 9
          LLL++G+P
Sbjct: 8  LLLALGLP 15
>XP_006716441
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLLSIGVP 9
           LLLS G+P
Sbjct: 333 LLLSTGMP 340
>NP_612153
          Length = 281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ILLLSIGVP 9
          +LLL++G P
Sbjct: 7  LLLLALGCP 15
>NP_001161870
          Length = 278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LLLSIGV 8
          LLLS+G+
Sbjct: 56 LLLSVGI 62
>NP_001120916
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>NP_001001547
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>NP_000063
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>NP_006407
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LLLSIGV 8
          LLLS+G+
Sbjct: 56 LLLSVGI 62
>NP_001001548
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>NP_001120915
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>NP_001276838
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           ++LLS+GV
Sbjct: 386 MILLSVGV 393
>NP_001276837
          Length = 433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           ++LLS+GV
Sbjct: 407 MILLSVGV 414
>NP_004922
          Length = 210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           +LL+S+GV
Sbjct: 182 VLLVSLGV 189
>NP_001276840
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           ++LLS+GV
Sbjct: 370 MILLSVGV 377
>NP_757362
          Length = 243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           +LL+S+GV
Sbjct: 182 VLLVSLGV 189
>NP_742099
          Length = 221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           +LL+S+GV
Sbjct: 182 VLLVSLGV 189
>NP_647479
          Length = 988

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LLLSIGVP 9
           L LSIG P
Sbjct: 392 LALSIGTP 399
>NP_758963
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LLLSIGVP 9
           L LSIG P
Sbjct: 392 LALSIGTP 399
>NP_057062
          Length = 835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILLLSIGVP 9
           ILLL  G+P
Sbjct: 445 ILLLRAGLP 453
>NP_056222
          Length = 271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ILLLSIGVP 9
          +LLL +G+P
Sbjct: 45 MLLLYVGLP 53
>NP_001269596
          Length = 955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLSIGVP 9
           LLS+G+P
Sbjct: 913 LLSLGLP 919
>NP_001269595
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLSIGVP 9
           LLS+G+P
Sbjct: 934 LLSLGLP 940
>NP_001106279
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILLLSIGVP 9
           ILLL  G+P
Sbjct: 559 ILLLRAGLP 567
>NP_001186256
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILLLSIGVP 9
           ILLL  G+P
Sbjct: 559 ILLLRAGLP 567
>NP_003096
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ILLLSIGV 8
            ++LLS+GV
Sbjct: 2146 LILLSLGV 2153
>XP_006726853
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LLSIGVP 9
          LLS+G+P
Sbjct: 75 LLSLGLP 81
>XP_006723596
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LLSIGVP 9
          LLS+G+P
Sbjct: 75 LLSLGLP 81
>XP_005253308
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLSIGVP 9
           LLS+G+P
Sbjct: 970 LLSLGLP 976
>XP_005250772
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>XP_005250771
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>XP_005250770
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLLSIGV 8
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>XP_005244926
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ILLLSIGVP 9
          +LLL  GVP
Sbjct: 5  LLLLICGVP 13
>NP_001956
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LLSIGVP 9
           LLS+G P
Sbjct: 313 LLSVGAP 319
>NP_001138526
          Length = 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLLSIGVP 9
           +LLS GVP
Sbjct: 555 VLLSSGVP 562
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.162    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 506,908
Number of extensions: 1134
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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