Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     665
NP_001075109                                                           19     665
NP_061915                                                              18    1935
XP_005250520                                                           18    1935
XP_006716093                                                           18    1935
XP_005250519                                                           18    1935
NP_945347                                                              17    2528
XP_006724029                                                           17    2528
XP_005260981                                                           17    2528
XP_006724028                                                           17    2528
XP_005260979                                                           17    2528
XP_005260978                                                           17    2528
XP_005260977                                                           17    2528
NP_000284                                                              16    5631
NP_001027005                                                           16    5631
NP_001080                                                              16    5631
NP_001361                                                              16    5631
XP_005256041                                                           16    5631
XP_005256040                                                           16    5631
XP_006712019                                                           16    5631
NP_001116513                                                           16    7355
NP_001116868                                                           16    7355
NP_000570                                                              16    7355
NP_001093638                                                           16    7355
NP_055951                                                              16    7355
NP_001264044                                                           16    7355
NP_776161                                                              16    7355
NP_000848                                                              16    7355
NP_001010977                                                           16    7355
NP_056081                                                              16    7355
NP_001247420                                                           16    7355
XP_006723821                                                           16    7355
XP_006723820                                                           16    7355
XP_006723819                                                           16    7355
XP_005263016                                                           16    7355
XP_005265032                                                           16    7355
XP_005265031                                                           16    7355
XP_005265030                                                           16    7355
NP_490597                                                              15    9605
NP_005391                                                              15    9605
NP_055114                                                              15    9605
NP_055483                                                              15    9605
NP_001275918                                                           15    9605
NP_001159451                                                           15    9605
NP_003624                                                              15    9605
NP_001269385                                                           15    9605
NP_001243503                                                           15    9605
NP_001243505                                                           15    9605
NP_001243504                                                           15    9605
NP_057425                                                              15    9605
NP_443159                                                              15    9605
NP_004524                                                              15    9605
NP_001253964                                                           15    9605
XP_006717953                                                           15    9605
XP_006717952                                                           15    9605
XP_006717951                                                           15    9605
XP_006717950                                                           15    9605
XP_006717949                                                           15    9605
XP_006717948                                                           15    9605
XP_005265871                                                           15    9605
XP_006714880                                                           15    9605
XP_005265870                                                           15    9605
XP_005264488                                                           15    9605
XP_005264486                                                           15    9605
XP_005264485                                                           15    9605
XP_005246254                                                           15    9605
XP_005246253                                                           15    9605
XP_005246252                                                           15    9605
XP_006711970                                                           15    9605
XP_006711969                                                           15    9605
XP_005246249                                                           15    9605
XP_006711968                                                           15    9605
XP_006711967                                                           15    9605
NP_001124336                                                           15    9605
NP_694948                                                              15    9605
NP_056246                                                              15    9605
>NP_008835
          Length = 4128

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LFSGILKE 9
            LFSGILKE
Sbjct: 2812 LFSGILKE 2819
>NP_001075109
          Length = 4097

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    LFSGILKE 9
            LFSGILKE
Sbjct: 2812 LFSGILKE 2819
>NP_061915
          Length = 661

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FSGILKE 9
           FSGILKE
Sbjct: 126 FSGILKE 132
>XP_005250520
          Length = 661

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FSGILKE 9
           FSGILKE
Sbjct: 126 FSGILKE 132
>XP_006716093
          Length = 667

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FSGILKE 9
           FSGILKE
Sbjct: 126 FSGILKE 132
>XP_005250519
          Length = 667

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   FSGILKE 9
           FSGILKE
Sbjct: 126 FSGILKE 132
>NP_945347
          Length = 481

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           LF G+LKE
Sbjct: 327 LFKGVLKE 334
>XP_006724029
          Length = 398

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           LF G+LKE
Sbjct: 335 LFKGVLKE 342
>XP_005260981
          Length = 404

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           LF G+LKE
Sbjct: 335 LFKGVLKE 342
>XP_006724028
          Length = 404

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           LF G+LKE
Sbjct: 335 LFKGVLKE 342
>XP_005260979
          Length = 459

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           LF G+LKE
Sbjct: 305 LFKGVLKE 312
>XP_005260978
          Length = 483

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           LF G+LKE
Sbjct: 335 LFKGVLKE 342
>XP_005260977
          Length = 489

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           LF G+LKE
Sbjct: 335 LFKGVLKE 342
>NP_000284
          Length = 1093

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LFSGILK 8
           LFSG+LK
Sbjct: 867 LFSGMLK 873
>NP_001027005
          Length = 1086

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LFSGILK 8
           LFSG+LK
Sbjct: 860 LFSGMLK 866
>NP_001080
          Length = 1704

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ILFSGIL 7
          +LFSGIL
Sbjct: 33 LLFSGIL 39
>NP_001361
          Length = 4158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ILFSGILKE 9
            +LFSGI+ +
Sbjct: 1690 LLFSGIISD 1698
>XP_005256041
          Length = 1086

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LFSGILK 8
           LFSG+LK
Sbjct: 860 LFSGMLK 866
>XP_005256040
          Length = 1093

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LFSGILK 8
           LFSG+LK
Sbjct: 867 LFSGMLK 873
>XP_006712019
          Length = 4158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ILFSGILKE 9
            +LFSGI+ +
Sbjct: 1690 LLFSGIISD 1698
>NP_001116513
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILFSGILK 8
           I +SGILK
Sbjct: 220 ICYSGILK 227
>NP_001116868
          Length = 360

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILFSGILK 8
           I +SGILK
Sbjct: 220 ICYSGILK 227
>NP_000570
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILFSGILK 8
           I +SGILK
Sbjct: 212 ICYSGILK 219
>NP_001093638
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILFSGILK 8
           I +SGILK
Sbjct: 212 ICYSGILK 219
>NP_055951
          Length = 2570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LFSGILK 8
            +FSG+LK
Sbjct: 1739 IFSGLLK 1745
>NP_001264044
          Length = 4516

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LFSGILKE 9
            LFS IL+E
Sbjct: 2237 LFSSILRE 2244
>NP_776161
          Length = 990

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FSGILKE 9
           FSG++KE
Sbjct: 208 FSGLVKE 214
>NP_000848
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILFSGIL 7
           ILFSGI+
Sbjct: 422 ILFSGIV 428
>NP_001010977
          Length = 264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LFSGILK 8
           LF GILK
Sbjct: 256 LFKGILK 262
>NP_056081
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILFSGIL 7
           ILFSGI+
Sbjct: 324 ILFSGIV 330
>NP_001247420
          Length = 597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILFSGIL 7
           ILFSGI+
Sbjct: 340 ILFSGIV 346
>XP_006723821
          Length = 334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ILFSGIL 7
          ILFSGI+
Sbjct: 77 ILFSGIV 83
>XP_006723820
          Length = 334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ILFSGIL 7
          ILFSGI+
Sbjct: 77 ILFSGIV 83
>XP_006723819
          Length = 614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILFSGIL 7
           ILFSGI+
Sbjct: 357 ILFSGIV 363
>XP_005263016
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILFSGIL 7
           ILFSGI+
Sbjct: 397 ILFSGIV 403
>XP_005265032
          Length = 2545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LFSGILK 8
            +FSG+LK
Sbjct: 1739 IFSGLLK 1745
>XP_005265031
          Length = 2569

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LFSGILK 8
            +FSG+LK
Sbjct: 1739 IFSGLLK 1745
>XP_005265030
          Length = 2595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LFSGILK 8
            +FSG+LK
Sbjct: 1739 IFSGLLK 1745
>NP_490597
          Length = 1362

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SGILKE 9
           SGILKE
Sbjct: 358 SGILKE 363
>NP_005391
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1 ILFSGILK 8
         ++F+G+LK
Sbjct: 2 VVFNGLLK 9
>NP_055114
          Length = 722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SGILKE 9
           SGILKE
Sbjct: 358 SGILKE 363
>NP_055483
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ILFSGIL 7
            +LFSG+L
Sbjct: 1869 LLFSGLL 1875
>NP_001275918
          Length = 2286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ILFSGILK 8
            +LFSG+L+
Sbjct: 997  MLFSGLLE 1004
>NP_001159451
          Length = 1994

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILFSGILK 8
           +LFSG+L+
Sbjct: 689 MLFSGLLE 696
>NP_003624
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LFSGILKE 9
          +FSG LKE
Sbjct: 74 MFSGGLKE 81
>NP_001269385
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           + SG+LKE
Sbjct: 121 VISGVLKE 128
>NP_001243503
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LFSGILKE 9
          +FSG LKE
Sbjct: 74 MFSGGLKE 81
>NP_001243505
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2 LFSGILKE 9
         +FSG LKE
Sbjct: 1 MFSGGLKE 8
>NP_001243504
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LFSGILKE 9
          +FSG LKE
Sbjct: 74 MFSGGLKE 81
>NP_057425
          Length = 2302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ILFSGILK 8
            +LFSG+L+
Sbjct: 997  MLFSGLLE 1004
>NP_443159
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           LFSG+L +
Sbjct: 184 LFSGVLMD 191
>NP_004524
          Length = 1141

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FSGILKE 9
           FSG+LK+
Sbjct: 184 FSGLLKK 190
>NP_001253964
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           LFSG+L +
Sbjct: 184 LFSGVLMD 191
>XP_006717953
          Length = 2008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILFSGILK 8
           +LFSG+L+
Sbjct: 689 MLFSGLLE 696
>XP_006717952
          Length = 2300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ILFSGILK 8
            +LFSG+L+
Sbjct: 997  MLFSGLLE 1004
>XP_006717951
          Length = 2315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ILFSGILK 8
            +LFSG+L+
Sbjct: 997  MLFSGLLE 1004
>XP_006717950
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ILFSGILK 8
            +LFSG+L+
Sbjct: 997  MLFSGLLE 1004
>XP_006717949
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ILFSGILK 8
            +LFSG+L+
Sbjct: 997  MLFSGLLE 1004
>XP_006717948
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ILFSGILK 8
            +LFSG+L+
Sbjct: 997  MLFSGLLE 1004
>XP_005265871
          Length = 229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           LFSG+L +
Sbjct: 184 LFSGVLMD 191
>XP_006714880
          Length = 232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           LFSG+L +
Sbjct: 184 LFSGVLMD 191
>XP_005265870
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           LFSG+L +
Sbjct: 184 LFSGVLMD 191
>XP_005264488
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1 ILFSGILK 8
         ++F+G+LK
Sbjct: 2 VVFNGLLK 9
>XP_005264486
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1 ILFSGILK 8
         ++F+G+LK
Sbjct: 2 VVFNGLLK 9
>XP_005264485
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1 ILFSGILK 8
         ++F+G+LK
Sbjct: 2 VVFNGLLK 9
>XP_005246254
          Length = 947

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ILFSGIL 7
           +LFSG+L
Sbjct: 867 LLFSGLL 873
>XP_005246253
          Length = 1038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ILFSGIL 7
           +LFSG+L
Sbjct: 958 LLFSGLL 964
>XP_005246252
          Length = 1850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ILFSGIL 7
            +LFSG+L
Sbjct: 1770 LLFSGLL 1776
>XP_006711970
          Length = 1948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ILFSGIL 7
            +LFSG+L
Sbjct: 1868 LLFSGLL 1874
>XP_006711969
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ILFSGIL 7
            +LFSG+L
Sbjct: 1869 LLFSGLL 1875
>XP_005246249
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ILFSGIL 7
            +LFSG+L
Sbjct: 1869 LLFSGLL 1875
>XP_006711968
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ILFSGIL 7
            +LFSG+L
Sbjct: 1869 LLFSGLL 1875
>XP_006711967
          Length = 1949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    ILFSGIL 7
            +LFSG+L
Sbjct: 1869 LLFSGLL 1875
>NP_001124336
          Length = 755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LFSGILKE 9
           LFSG+L +
Sbjct: 184 LFSGVLMD 191
>NP_694948
          Length = 328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SGILKE 9
           SGILKE
Sbjct: 120 SGILKE 125
>NP_056246
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LFSGILK 8
           LFSG+L+
Sbjct: 439 LFSGLLR 445
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.157    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 531,435
Number of extensions: 994
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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